Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Director of Client Success (Managed Transportation)
$100K - $140K *
Lead the charge in driving revenue growth and client retention by managing strategic relationships and optimizing operational strategies for a diverse portfolio of enterprise clients in the transporta...
3 days ago
$95K - $115K *
Develop and lead VDC processes and best practices, managing resources across projects. Collaborate with teams to enhance virtual building culture and ensure effective execution throughout the project...
2 weeks ago
$88K - $105K *
Lead a dynamic team in overseeing sewer and drainage project reviews, ensuring compliance and strategic alignment with district goals while fostering collaboration with public officials and stakeholde...
Yesterday
Senior Director, Business Development
$169K - $255K *
Shape the future of personalized consumer products by driving strategic partnerships and revenue growth. Lead business development efforts, cultivate relationships, and expand market reach to position...
Reposted 4 days ago
Senior Director, Business Development
$169K - $255K *
Join a team that's driving growth through strategic partnerships in personalized consumer products. Lead initiatives to expand market reach and revenue streams while collaborating across functions to...
2 weeks ago
Senior Engineering Manager, Member Experience
$202K - $253K *
Elevate your leadership as you drive engineering excellence, overseeing multiple squads from prototype to production. Shape the roadmap, empower teams, and ensure quality delivery while staying techni...
Reposted yesterday
$110K - $130K *
Transform construction project delivery by managing all phases, ensuring timely, budget-friendly, and quality outcomes. Collaborate with cross-functional teams to align solutions with business needs a...
1 week ago
$110K - $130K *
Drive CQV excellence for capital projects in a GMP-regulated environment, ensuring compliance and timely execution. Lead teams through commissioning, qualification, and operational handover of critica...
3 days ago
$95K - $113K *
Manage project lifecycles to exceed client expectations, ensuring timely communication and risk management while fostering collaboration and mentoring within teams to achieve project goals and profita...
2 weeks ago
$95K - $113K *
Manage project lifecycles to exceed client expectations, ensuring timely communication and risk management. Foster collaboration across teams, mentor peers, and uphold safety and quality standards whi...
2 weeks ago
Project Manager (Remote) - Data Center Construction Projects
$120K - $150K *
Transform complex data center projects by leading design and construction efforts. Collaborate with diverse stakeholders to ensure successful project delivery while managing multiple initiatives acros...
1 week ago
Principal Technical Program Manager, Engineering
$180K - $240K *
Drive cross-domain visibility and coordination in a dynamic engineering environment. As the sole TPM, you'll ensure programs are on track, dependencies are mapped, and automation enhances efficiency a...
1 week ago
$95K - $115K *
Join our dynamic team as a Finance Manager, where you'll lead financial analysis, develop models, and present insights to senior leadership, driving growth and accuracy in financial reporting across t...
1 week ago
Senior Product Manager, Consumer
$120K - $145K *
Empower consumer experiences by leading product strategy and execution for innovative genomics solutions. Collaborate with cross-functional teams to enhance user satisfaction and drive adoption throug...
2 weeks ago
$103K - $185K *
Join a team that's focused on hands-on technical delivery while mentoring and developing team capabilities. Lead solution implementation, troubleshoot issues, and establish best practices to ensure hi...
1 week ago
Staff Product Manager, Growth & E-commerce Experimentation
$161K - $190K *
Transform the digital commerce experience by owning a high-velocity experimentation roadmap. Collaborate across teams to enhance customer journeys, improve conversion rates, and establish a robust exp...
4 weeks ago
$150K - $195K *
Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...
4 weeks ago
Product Manager - Acxiom B2B Suite
$110K - $130K *
Engineer innovative data products that empower global businesses. Lead cross-functional teams to define product strategy, manage lifecycles, and drive performance metrics, ensuring alignment with mark...
3 weeks ago
$130K - $219K *
Engage with customers to identify key challenges and drive product innovation. Collaborate across hardware, software, and AI teams to deliver impactful solutions that enhance physical operations and g...
2 weeks ago
SAP MDG Manager / General SAP Data Governance
$124K - $280K *
Elevate client data governance by leading SAP MDG initiatives, enhancing master data quality, and aligning processes. Guide teams through complex transformations while delivering strategic recommendat...
Yesterday
SAP MDG Manager / General SAP Data Governance
$124K - $280K *
Champion SAP data governance initiatives, guiding teams to enhance master data quality and streamline processes. Leverage your expertise to drive client success in complex transformation programs whil...
Yesterday
$110K - $130K *
Optimize program delivery by leading complex projects from proposal to execution. Drive cross-functional collaboration, manage budgets, and ensure customer commitments are met while mentoring junior p...
3 weeks ago
Document Review Project Manager (JD Required)
$100K - $120K *
Lead document review projects by optimizing workflows and technology. Collaborate with counsel and internal teams to ensure quality and efficiency in deliverables, driving down costs while enhancing a...
4 days ago
Senior Manager, EPC Estimation
$120K - $145K *
Oversee global EPC proposal processes for Battery Energy Storage Systems, collaborating with cross-functional teams to deliver innovative, customer-centric solutions while driving continuous improveme...
3 weeks ago
Project Manager- Municipal Infrastructure
$125K - $145K *
Unlock potential by leading complex multi-disciplinary projects to achieve client goals, overseeing contracting, risk management, and deliverable production, while supporting program growth and commun...
Reposted 3 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.