Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Project Manager - Data Center
$110K - $130K *
Drive project success by leading high-value construction initiatives from concept to completion. Collaborate with diverse teams, manage budgets, and ensure safety while mentoring staff to deliver inno...
2 weeks ago
$95K - $115K *
Advance your career by leading complex projects that drive strategic goals. Collaborate with cross-functional teams to ensure timely delivery, compliance, and risk management while enhancing business...
4 weeks ago
$100K - $120K *
Lead the charge in managing complex projects that drive strategic goals. Oversee project lifecycles, ensuring timely delivery, compliance, and stakeholder engagement while fostering collaboration acro...
4 weeks ago
Project Manager, Congress Planning
$110K - $148K *
Transform global congress planning by leading cross-functional teams, managing timelines, and ensuring quality execution. Drive strategic alignment and operational excellence to deliver impactful cong...
Yesterday
$110K - $130K *
Optimize our product suite to elevate financial advisory capabilities through innovative AI solutions. Lead the entire product lifecycle, collaborating with diverse teams to transform complex workflow...
Reposted 1 week ago
$100K - $150K *
Lead the charge in managing complex, technically sophisticated projects, focusing on data centers. Collaborate with diverse stakeholders to ensure project alignment with client goals, budgets, and sch...
Reposted yesterday
Project Manager, Preconstruction OS
$108K - $130K *
Drive the delivery of a preconstruction platform by managing vendor engagement, overseeing validation phases, and ensuring quality gates are met. Collaborate across teams to achieve a production-ready...
3 weeks ago
$195K - $230K *
Drive growth by leading go-to-market strategies for TMC partnerships, building and executing plans from the ground up. Collaborate cross-functionally to influence product development and represent the...
3 weeks ago
Director, Digital Product Management
$150K - $180K *
Lead the strategy and development of digital publishing products, enhancing workflows and user experiences. Collaborate across teams to create a cohesive ecosystem that supports efficient content mana...
2 days ago
Technical Program Manager (TPM)
$115K - $145K *
Engineer innovative systems and processes to enhance product delivery, ensuring cross-functional teams operate efficiently and effectively. Drive execution, manage stakeholder alignment, and facilitat...
3 weeks ago
$77K - $91K *
Lead the charge in delivering exceptional project management services, ensuring seamless communication and collaboration with builders while achieving safety and quality goals throughout the project l...
2 weeks ago
Senior Manager, Product Security Office
$200K - $250K *
Champion product security initiatives by leading a skilled team, architecting compliance frameworks, and managing incident response to enhance trust across all products and stakeholders...
1 week ago
$159K - $287K *
Drive growth and lead strategic partnerships as you oversee P&L performance and business strategy for key global accounts, ensuring operational excellence and customer satisfaction while managing high...
Reposted 2 days ago
$90K - $120K *
Champion project success by leading data center initiatives, ensuring quality delivery, profitability, and strong customer relationships while managing teams and coordinating with departments to meet...
1 week ago
Strategic Project Lead - Finance
$100K - $120K *
Elevate your career by leading strategic finance pilots to drive AI model training and evaluation. This hands-on role combines financial expertise and operational leadership to transform emerging proj...
Reposted 4 days ago
$135K - $160K *
Shape the future of homebuilding by leading a small team of engineers to develop innovative solutions. Balance technical ownership and people leadership while driving impactful projects from concept t...
Reposted 4 days ago
$122K - $177K *
Unlock potential by leading HRIS strategy and optimization, overseeing a team to enhance Workday and UKG systems. Drive transformation and collaboration across HR, Finance, and Operations for impactfu...
2 weeks ago
21GRAMS- Senior Project Manager
$110K - $115K *
Join a team that's redefining healthcare project management. Lead integrated initiatives, mentor talent, and drive excellence across diverse campaigns while fostering collaboration and innovation in a...
2 weeks ago
Senior Program Manager - Data Center Construction
$110K - $130K *
Take ownership of large-scale construction projects, managing stakeholders and ensuring compliance. Oversee project governance, track milestones, and enhance processes while fostering client relations...
4 days ago
$148K - $193K *
Join a dynamic team as a Program Manager, leading complex projects from inception to completion. Collaborate with diverse stakeholders, manage resources, and drive innovation while ensuring client sat...
3 weeks ago
$88K - $105K *
Join our team to lead IT projects that enhance technology and optimize processes. Collaborate across functions to drive improvements, ensuring alignment with business goals while fostering a culture o...
1 week ago
$140K - $160K *
Elevate financial planning and analysis as you lead consolidated forecasts, enhance reporting quality, and partner with executives to drive strategic decisions. Utilize AI and automation to optimize p...
Reposted 3 days ago
$143K - $208K *
Join a dynamic team as you lead enterprise-wide manufacturing strategy, ensuring performance and scalability across multiple facilities while driving cross-functional collaboration and continuous impr...
1 week ago
$155K - $410K *
Transform your career by leading large-scale SAP implementations, setting strategic direction, and mentoring future leaders while ensuring operational efficiency and client alignment across multiple e...
3 weeks ago
$155K - $410K *
Shape the future of SAP implementation by leading large-scale programs, defining strategic objectives, and mentoring teams to deliver innovative solutions that enhance operational efficiency and clien...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.