Find $100K+ Jobs in Michigan

Explore professional opportunities in Michigan with salaries of $100,000 or more. From Detroit and Grand Rapids to Ann Arbor, Lansing, and communities across the state, Ladders helps experienced professionals discover vetted roles with competitive compensation.

Explore Michigan Opportunities Across Industries

Michigan’s economy spans automotive and advanced manufacturing, healthcare, technology, finance, education, energy, and professional services. Browse senior-level and specialized openings that match your experience, skills, and career goals.

Search by Location and Career Goals

Find opportunities in major employment centers such as Detroit, Ann Arbor, Grand Rapids, and Lansing, or consider roles elsewhere in Michigan. Compare positions by responsibilities, location, work arrangement, and compensation to focus your search.

Advance Your Career with Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more. Create a profile, refine your search, and explore Michigan roles that align with your expertise and next career move. Job availability and compensation vary by employer and position.

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$120K - $140K *

Shape the future of federal financial operations by driving user adoption and change management for a new tool. Collaborate with stakeholders to enhance user experience, streamline processes, and ensu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $140K *

Lead the charge in enhancing our Partner ecosystem by managing relationships and driving growth initiatives. Oversee onboarding, operations, and support for System Integrators while implementing autom...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$181K - $225K *

Lead the charge in operationalizing complex clinical studies globally, collaborating with cross-functional teams to enhance proposal development and manage global lab relationships, ensuring strategic...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$181K - $225K *

Lead the charge in advancing scientific operations within a dynamic team, driving global lab relationships and supporting complex clinical studies. Collaborate across functions to ensure strategic, op...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $150K *

Shape impactful health initiatives by providing expert project management support to the CDC's Office of the Director, ensuring effective prioritization, coordination, and execution of programs in a d...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$170K - $243K *

Transform product innovation by leading AI-driven strategies and experiments, collaborating across teams to enhance software solutions and improve employee experiences in a dynamic, fast-paced environ...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$205K - $380K *

Drive transformative supply chain initiatives, providing strategic leadership and operational oversight to enhance efficiency and best practices across client hospitals. Collaborate with C-suite execu...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$131K - $176K *

Oversee global Contract Manufacturing partnerships, driving productivity and ensuring quality goals are met. Collaborate cross-functionally to support new product launches and process improvements, wh...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $172K *

Unlock potential by leading product initiatives for 360e Facility Coding, collaborating with diverse teams to enhance customer experiences and drive business value through innovative solutions and eff...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Unlock new opportunities as you drive business growth in the life sciences sector. Focus on building relationships and matching client needs with innovative solutions in commercial consulting, brand c...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$208K - $306K *

Join a team that's redefining engineering excellence by leading platform services that enhance software development. Drive innovation, consolidate capabilities, and foster a culture of collaboration t...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate contract management by overseeing agreements across logistics operations. Collaborate with Legal, Commercial, and Operations teams to ensure compliance, drive renewals, and support negotiation...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Transportation

$110K - $130K *

Drive impactful automotive projects as a Traveling Senior Project Manager, overseeing budgets, schedules, and teams across multiple states. Lead with expertise, mentor others, and ensure project succe...

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$125K - $185K *

Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Shape the future of application development by leading a dynamic team to create AI-driven solutions that enhance user experience and operational efficiency, while collaborating closely with employees...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$183K - $215K *

Shape the future of North American inland transportation by leading product strategy and development. Collaborate with cross-functional teams to deliver actionable insights and drive market success in...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $125K *

Drive the vision and strategy for analytics products, enhancing client insights and program value. Collaborate across teams to deliver AI-enabled solutions, ensuring seamless integration and measurabl...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$188K - $245K *

Drive innovative UX design strategies in clinical settings, leading a talented team to enhance decision support and care coordination. Collaborate across functions to integrate AI and elevate user exp...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead and oversee open pit sand mining operations, managing production and plant activities while ensuring compliance with safety regulations and optimizing resources for efficiency and effectiveness...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Drive full-cycle sales for global clinical operations, fostering client relationships and developing strategic plans for service growth in alignment with company objectives...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive enterprise growth by engaging top health system executives, transforming clinical outcomes through innovative solutions, and building strategic partnerships to expand market presence and adoptio...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$119K - $190K *

Shape the future of our Corporate Functions by partnering with senior leaders to drive talent strategy, organizational effectiveness, and leadership development. Leverage data and insights to influenc...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive integration strategy and lead engineering teams to design, implement, and support enterprise integrations. Engage hands-on to troubleshoot and validate APIs, ensuring seamless connectivity acros...

4 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$95K - $115K *

Lead the charge in optimizing plant operations, driving safety, quality, and productivity while fostering a culture of continuous improvement and teamwork in a dynamic manufacturing environment...

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $130K *

Lead the charge in clinical study start-up operations, driving team development and ensuring timely site activation. Collaborate cross-functionally to enhance processes, meet regulatory standards, and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs can I find in Michigan?question toggle

    Listings may include leadership, technology, engineering, healthcare, finance, sales, and other specialized professional roles. Availability depends on current employer postings.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities may be available in Detroit, Grand Rapids, Ann Arbor, Lansing, and other Michigan communities. Check each listing for its location and work arrangement.

  • Are all jobs on Ladders in Michigan guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more, but review each listing for its specific compensation details and eligibility requirements.

  • Can I find remote or hybrid jobs based in Michigan?question toggle

    Some employers may offer remote or hybrid arrangements. Work location and flexibility vary by role, so confirm the details in each job posting.