Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$160K - $190K *

Champion project control excellence by developing strategies, collaborating with teams, and optimizing performance to ensure successful project delivery within timelines and budgets. Lead initiatives...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$257K - $347K *

Transform the future of AI by leading the design and operation of the OPUS Brain, a cognitive architecture that empowers agents across supply chain processes. Drive innovation, governance, and collabo...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$129K - $205K *

Accelerate progress at a leading healthcare organization by guiding strategic finance initiatives across a $2B revenue geography. Collaborate with senior leaders to drive growth, influence enterprise...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $200K *

Lead and evolve omnichannel strategy across diverse clients and brands, driving integrated customer experiences that align with business objectives while enhancing strategic capabilities in a dynamic...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Champion best practices in vendor management with a focus on strategic sourcing, risk mitigation, and client relationship cultivation to drive operational excellence and maximum value across client en...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$171K - $321K *

Join a team that's redefining global Learning Services strategy and execution. Lead a multidisciplinary group to modernize digital learning, enhance customer engagement, and drive business growth thro...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$156K - $235K *

Unlock potential by leading strategic sales initiatives to drive new client acquisition in healthcare. Collaborate with teams to enhance operational effectiveness and deliver exceptional client experi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$195K - $215K *

Elevate your career by leading clinical contracts strategy to drive global trials. Collaborate with diverse teams, shape negotiation approaches, and ensure compliance while developing a high-performin...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to enhancing customer success through expert guidance in Privilege Access Management. Leverage your technical skills to support enterprise clients, ensuring seamless deplo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Transform healthcare delivery by leading program initiatives that drive partner success in value-based care. Utilize data-driven strategies to manage launch processes, ensuring alignment across teams...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Drive the future of commercial technology and data engineering by leading a multidisciplinary team to deliver scalable solutions that enhance analytics, digital engagement, and operational efficiency...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a dynamic team to design and develop engaging learning programs that enhance workforce skills. Leverage your expertise in instructional design and technology to create scalable training solutions...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$120K - $150K *

Transform the supply chain landscape by leading procurement and subcontracting efforts, ensuring compliance with federal regulations while driving efficiency and innovation in support of critical defe...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$74K - $92K *

Champion project success by providing vital administrative support to the Transit and Rail team, ensuring efficient project execution through budget management, scheduling, and contract coordination w...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$190K *

Lead our product marketing efforts to drive strategy, market growth, and segmentation for innovative public safety software. Collaborate with teams to translate product features into compelling messag...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$81K - $101K *

Join a team that's dedicated to enhancing quality and process improvement. Lead initiatives, interact with customers and suppliers, and mentor staff to ensure compliance and excellence in product qual...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$120K - $140K *

Shape the future of Microsoft 365 management by defining and delivering security, governance, and multi-tenant capabilities. Collaborate with cross-functional teams to enhance product offerings and en...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$96K - $145K *

Drive product strategy and innovation for semiconductor inspection solutions, leading cross-functional teams to define product requirements and address market needs while ensuring alignment with busin...

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$93K - $159K *

Advance your career by developing and standardizing Procurement processes that enhance compliance and efficiency. Collaborate with cross-functional teams to create clear documentation and governance p...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$93K - $159K *

Optimize procurement processes by developing standardized workflows and governance materials. Collaborate with cross-functional teams to ensure compliance and efficiency in sourcing, contracting, and...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $125K *

Lead the transformation of patient care by overseeing a dynamic case management program, ensuring optimal clinical outcomes and financial performance through effective team collaboration and resource...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $190K *

Lead the charge in shaping data platform strategies and governance, driving innovative solutions and team development. Collaborate with partners to enhance AI readiness and ensure successful technical...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Lead a dynamic team in managing customer orders, ensuring accuracy and timely delivery while enhancing interdepartmental collaboration and customer satisfaction across Sales and Service Delivery opera...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$274K - $457K *

Accelerate innovative clinical development strategies while leading cross-functional teams. Foster collaboration to ensure timely regulatory submissions and optimal trial execution within the internal...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$154K - $180K *

Join a team that's driving innovation in robotics development. You'll lead complex initiatives, collaborating across engineering, manufacturing, and supply chain to enhance operational efficiency and...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.