Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$80K - $95K *

Empower your career by leading a remote team in managing healthcare operations and compliance for a Federal IDRE program. Drive performance, enhance quality, and ensure regulatory adherence while fost...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead cross-functional hardware programs from concept to launch, aligning teams across engineering, design, and operations while mitigating risks and driving timely delivery through excellent project m...

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$167K - $300K *

Elevate your career by leading a high-impact CMC stability function, managing critical stability strategies across non-clinical, clinical, and commercial programs. Collaborate with diverse teams to en...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Build and lead a robust accounting function, ensuring accurate U.S. GAAP reporting, scalable processes, and strong internal controls to support growth and complex financial arrangements in a dynamic b...

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $240K *

Elevate your career by leading internal management and driving strategic priorities. As a key member of the Executive Leadership Team, you'll optimize operations, coach department leads, and ensure al...

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Champion preconstruction initiatives for large-scale commercial projects, ensuring accurate estimates, client satisfaction, and alignment with company goals through effective communication and relatio...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform frontline manager development by leading strategic programs that enhance coaching, deal inspection, and pipeline management. Collaborate cross-functionally to drive consistent team performan...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $236K *

Drive strategic decision-making by evaluating investment alternatives and lifecycle opportunities. Collaborate with cross-functional teams to optimize portfolio value and support program planning thro...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Elevate your career by managing comprehensive HR operations, fostering employee relations, and ensuring compliance. Collaborate across teams while driving strategic initiatives and providing hands-on...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$100K - $120K *

Join a team that's focused on delivering successful project outcomes by building comprehensive schedules, defining responsibilities, and managing timelines effectively to ensure client satisfaction an...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$75K - $90K *

Unlock potential by driving commercial growth and retention for a diverse portfolio of accounts. Manage relationships, execute renewals, and collaborate cross-functionally to ensure customer success a...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$75K - $90K *

Shape the future of customer relationships by driving retention and growth in a high-volume account management role. Collaborate cross-functionally to enhance client engagement and achieve commercial...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$348K - $471K *

Join a team that's driving operational excellence across a global B2B revenue engine. You'll lead revenue planning, forecasting, and optimize the customer lifecycle to enable scalable growth across mu...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$82K - $95K *

Join our dynamic team to support and coordinate innovative automation projects. Collaborate with cross-functional teams, enhance processes, and contribute to impactful solutions while gaining valuable...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $125K *

Lead the development of innovative healthcare products, managing global New Product Development programs from concept to production while ensuring quality, budget, and schedule adherence across cross...

2 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$125K - $156K *

Drive data excellence by leading analytics initiatives, enhancing governance, and integrating systems. Collaborate with leadership to deliver impactful insights and ensure compliance while leveraging...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Staffing

$280K - $300K *

Pioneer innovative AI solutions in workforce management, leading product development from concept to deployment. Collaborate with engineers and executives to create impactful agentic products that enh...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Champion a robust security program, leading a team to achieve SOC 2 Type 2 attestation while ensuring secure engineering practices across diverse products and cloud environments. Drive compliance, ris...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$320K - $380K *

Drive the strategy and execution of the Materials Science AISF program, ensuring alignment across complex, high-impact priorities while applying your deep domain expertise to advance AI capabilities i...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$151K - $204K *

Pioneer innovative manufacturing processes by leading a skilled engineering team. Drive strategic direction, optimize systems, and collaborate cross-functionally to enhance product development and ope...

2 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$142K - $167K *

Lead the charge in delivering impactful brand research solutions, managing multiple project teams, and fostering strong client relationships to drive revenue growth and client satisfaction in a dynami...

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$135K - $165K *

Elevate client outcomes by leading strategic media effectiveness initiatives, driving growth through insightful research and advisory. Collaborate with senior stakeholders to influence investment deci...

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$203K - $275K *

Manage client relationships and operational excellence by leading teams, ensuring financial compliance, and optimizing processes to enhance service delivery and achieve strategic goals...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Lead the charge in managing clinical projects, ensuring milestones are met while overseeing all operational aspects from start to finish. Collaborate with cross-functional teams and serve as the prima...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$170K - $185K *

Optimize payroll operations by leading a skilled team to deliver accurate, timely services across a complex organization. Drive compliance, enhance reporting capabilities, and implement innovative sol...

2 weeks ago

  •   8 - 10 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.