Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$157K - $283K *

Join a team that's driving growth in Texas transportation design services. Leverage your engineering and management expertise to enhance community projects, lead interdisciplinary teams, and build str...

United StatesRemote

1 week ago

  •   15+ years exp.  •   Real Estate & Construction

$110K - $130K *

Unlock your potential by leading clinical reimbursement and compliance across a multi-site skilled nursing portfolio. Collaborate closely with clinical teams to optimize documentation, reimbursement s...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$111K - $178K *

Transform project outcomes by leading cross-functional teams in hardware and ASIC development. Drive execution through key milestones while managing risks and stakeholder expectations to deliver innov...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$111K - $178K *

Join a dynamic team to lead complex hardware and ASIC development projects, driving innovation and collaboration across multi-functional teams to achieve successful product outcomes and business resul...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$81K - $130K *

Drive engineering excellence by leading complex programs from concept to production. Collaborate with cross-functional teams to ensure alignment, manage risks, and deliver successful outcomes while co...

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$81K - $130K *

Champion the execution of complex engineering programs, driving cross-functional team alignment from concept to production, ensuring stakeholder communication and program success through strategic pla...

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Champion superior client service by managing eDiscovery projects, coordinating teams, and strategizing solutions to meet client goals. Build strong relationships and ensure seamless communication betw...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$180K - $300K *

Join a team that's driving corporate development initiatives, managing M&A processes, and collaborating with leadership to identify and execute strategic acquisitions that enhance growth and innovatio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Lead the charge in transforming ideas into impactful products, owning the entire process from concept to launch. Collaborate closely with engineering and customers to deliver innovative solutions in a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$98K - $130K *

Lead the charge in financial and administrative operations within a dynamic systems engineering group, driving efficiency and collaboration while managing resources to support innovative technologies...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$263K - $292K *

Accelerate strategic biostatistics leadership in gene therapy, overseeing biometrics across clinical programs, design initiatives, and regulatory submissions while ensuring collaboration with cross-fu...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$141K - $239K *

Transform healthcare by leading product strategy for medication management workflows. Collaborate with cross-functional teams to enhance user experiences, streamline processes, and drive measurable ou...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$117K - $177K *

Lead a dynamic Managed Services Engineering team to enhance cloud operations, ensuring exceptional service delivery, compliance, and continuous improvement while driving team development and operation...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$108K - $145K *

Shape the future of project management as a Senior Cost Manager, driving cost efficiency and strategic decision-making. Collaborate with diverse teams to enhance client value and foster strong relatio...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$180K - $205K *

Drive financial excellence by delivering insights and analysis for the Field Service organization. Collaborate across departments to enhance forecasting, budgeting, and operational efficiency while su...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $140K *

Unlock potential by owning executive-level client relationships, driving integrated strategies, and leading action-oriented touchpoints that translate insights into measurable outcomes while championi...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Media

$109K - $130K *

Grow your career with a collaborative team focused on innovative healthcare architecture, driving project design and delivery while mentoring talent and ensuring design excellence from concept to cons...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Transform architecture strategy in a leading healthcare organization, driving innovation and collaboration across IT infrastructure while ensuring alignment with business and regulatory standards...

Massachusetts, USRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Staffing

$110K - $130K *

Drive clinical research operations for a multidisciplinary program focused on inflammatory and autoimmune diseases, ensuring rigorous execution of studies while collaborating with diverse teams to tra...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $235K *

Join a team that's redefining business processes through digital transformation. Lead cross-functional initiatives, ensuring scalable and standardized practices that align with strategic goals while f...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by driving product strategy and execution for data and identity solutions. Collaborate across teams to deliver impactful products, ensuring alignment with business goals and customer...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$192K - $256K *

Transform product strategy into market-ready offerings, driving revenue growth and adoption. Lead cross-functional teams to ensure successful product launches and alignment across Sales, Marketing, an...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$115K - $130K *

Lead the Archibus platform for a major Life Sciences client, driving enhancements and integrations while ensuring data integrity and user satisfaction. Collaborate with cross-functional teams to optim...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$105K - $150K *

Inspire impactful change by leading complex federal digital services programs. Oversee strategy, execution, and customer relationships while managing multidisciplinary teams to deliver high-quality te...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $155K *

Lead content operations for a federal web services program, managing a team to ensure timely, accurate, and accessible communication. Drive strategic planning, oversee Drupal content management, and e...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.