Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$135K - $160K *

Lead the development and optimization of LIMS solutions, managing teams and driving compliance with industry regulations to enhance laboratory workflows and data integrity...

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$73K - $132K *

Lead the charge in Agile delivery and technical documentation for AI initiatives, collaborating with cross-functional teams to ensure effective project execution and clear communication of complex con...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$145K - $168K *

Drive impactful medical congress operations by leading planning, execution, and cross-functional collaboration. Own vendor relationships and budgets while ensuring compliance and delivering high-quali...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $270K *

Join us to lead the Deal Desk within Strategic Finance, driving revenue adjustments and managing complex commercial agreements. Collaborate with cross-functional teams to ensure sound financial strate...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Media

$95K - $115K *

Drive the execution and scaling of AI-enabled cardiovascular care programs, collaborating across teams to enhance workflows and operational efficiency while ensuring continuous improvement in patient...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Drive complex client-facing projects in robotics and life sciences, managing timelines, budgets, and cross-functional teams. Collaborate closely with clients and engineers to ensure successful product...

Reposted yesterday

  •   Less than 5 years exp.  •   Staffing

$75K - $115K *

Create impactful project strategies by leading diverse teams and managing client expectations. Oversee high-volume projects across digital marketing, ensuring effective communication and efficient exe...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Media

$75K - $115K *

Manage cross-functional projects to deliver exceptional digital experiences and oversee junior project managers while executing innovative marketing strategies for high-profile clients in a dynamic te...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Media

$242K - $282K *

Lead the oversight of contractual matters across departments, serving as a trusted advisor to internal stakeholders from pre-clinical to commercial readiness. This role emphasizes collaboration and ex...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K *

Oversee the coordination of a multicenter clinical trial, managing day-to-day operations while supporting optometry practice functions. Collaborate with sites nationwide to ensure protocol adherence a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $180K *

Drive successful NPI programs by managing complex projects and collaborating with cross-functional teams to ensure alignment with customer needs. Elevate customer relationships and deliver strategic u...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$85K - $106K *

Accelerate progress at diverse building projects by supporting senior managers. Engage with clients, manage budgets, and ensure timely execution while developing your project management skills in a co...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $150K *

Unlock the potential of our platform by leading product improvements, enhancing workflows, and ensuring data integrity. Collaborate with cross-functional teams to drive measurable outcomes and elevate...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$80K - $105K *

Drive impactful environmental projects by managing site assessments, mentoring staff, and ensuring compliance with state regulations. Collaborate across services while supporting business development...

Today

  •   5 - 7 years exp.  •   Technical Services

$160K - $200K *

Elevate the technical architecture vision and execution across a product portfolio, driving the transition to a scalable, cloud-native SaaS environment while integrating AI, data, and security. Collab...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$155K - $186K *

Shape the future of strategic partnerships by leading initiatives that drive commercial success and foster collaboration across teams. Utilize your expertise in relationship management and negotiation...

Today

  •   5 - 7 years exp.  •   Business Services

$115K - $135K *

Shape the future of our Accounting Operations by leading a dynamic team, ensuring accuracy and efficiency in financial processes, and driving improvements through automation and AI integration...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Business Services

$91K - $118K *

Join a team that's transforming Services Operations through AI and automation. Collaborate with experts to quickly build and deploy innovative solutions, driving efficiency and scalability across proj...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Accelerate progress at the forefront of technology as you lead IT projects, ensuring timely delivery while aligning with strategic goals. Collaborate with diverse teams to manage risks, dependencies...

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$79K - $115K *

Champion large-scale program management by leading initiatives that align with strategic goals. Oversee project execution, stakeholder collaboration, and budget management while analyzing data and pro...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$230K - $280K *

Lead a high-performing team to enhance Solutions Consulting, drive cross-functional collaboration and ensure the success of strategic accounts through innovative, accountable deal execution and contin...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$127K - $153K *

Join our dynamic Business Development team to manage strategic partnerships, drive ecosystem strategies, and enhance collaboration across departments. Leverage your expertise to achieve measurable res...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$125K - $170K *

Champion the promotional review process by leading a team, optimizing operations, and enhancing technology solutions to ensure compliance and efficiency in marketing initiatives...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$101K - $154K *

Shape product strategy and commercialization efforts, ensuring alignment with market trends and customer needs. Drive product development, marketing initiatives, and cross-functional collaboration to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $155K *

Shape project success by leading engineering efforts, managing budgets, and ensuring compliance with industry standards. Collaborate with teams to deliver high-quality results on time and within scope...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.