Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Product Manager - Software Portfolio
$120K - $145K *
Lead the charge in shaping product strategy for a key software suite, driving market success by delivering user-focused solutions to major retailers while ensuring alignment with business objectives a...
1 month ago
Senior Digital Program Manager
$92K - $136K *
Help us drive customer success by owning and optimizing digital engagement programs. You'll lead strategy, build automated journeys, and analyze performance to enhance customer experiences and ensure...
2 weeks ago
Director, Global Risk & Resilience Program Governance
$150K - $180K *
Shape the future of resilience by leading enterprise-wide governance and strategy. Drive continuous improvement in business continuity, crisis management, and technology resilience while collaborating...
1 week ago
$100K - $120K *
Lead the charge in delivering SAP projects from start to finish, overseeing cross-functional teams and ensuring seamless integration, process improvements, and global template adoption for enhanced op...
Reposted 2 days ago
Dir. Product Manager, Digital & Growth AI Tech
$150K - $180K *
Innovate AI-driven growth strategies to enhance HCP and patient outcomes across the commercial funnel. Lead cross-functional teams to implement generative AI solutions, ensuring compliance and measura...
5 days ago
Director, R&D Portfolio Program Management
$175K - $220K *
Lead and develop a high-performing R&D project management team, overseeing a diverse portfolio of innovative projects. Drive effective execution while mentoring staff and enhancing cross-business proc...
Reposted 2 days ago
Senior Project and Program Manager, Marketing Brand Operations
$110K - $130K *
Optimize the Brand Design team's workflow by managing project intake, ensuring clear briefs, and maintaining organized processes. Collaborate with stakeholders to enhance efficiency and track delivera...
1 week ago
Project Manager II, Global Project Leadership
$95K - $115K *
Drive the successful delivery of complex global clinical trials, overseeing cross-functional teams and ensuring compliance with GCP and regulatory standards while managing budgets and timelines to exc...
3 weeks ago
$206K - $309K *
Elevate the Analyst Experience by owning strategy and outcomes for security workflows. Lead a team of product managers to unify analyst tools, drive customer migrations, and enhance product vision, en...
Today
Principal Business Technology Product Manager
$131K - $176K *
Shape the future of sales excellence by owning end-to-end seller experiences. You’ll optimize workflows, create impactful solutions, and directly influence our revenue systems through innovative produ...
Reposted 3 weeks ago
Director, Statistical Programming
$209K - $287K *
Pioneer innovative strategies in statistical programming, leading global submissions and ensuring compliance. Collaborate cross-functionally to enhance processes and drive excellence in drug developme...
3 days ago
$95K - $115K *
Unlock your potential as a Program Manager, leading federal service contracts and driving operational excellence. Collaborate with teams to ensure quality delivery, financial performance, and customer...
6 days ago
Program Manager, Onsite Data Collection
$110K - $130K *
Explore the dynamic role of a Program Manager, overseeing end-to-end data collection programs. Drive operational excellence, client satisfaction, and strategic execution in a fast-paced environment, e...
1 week ago
Senior Director, Capacity Planning, Workforce Operations & Analytics
$232K - $290K *
Lead the charge in optimizing workforce operations and analytics for multi-condition health care services. Develop strategies for capacity planning, staffing, and analytics to drive efficiency and sup...
Reposted 4 weeks ago
Implementation Project Manager
$90K - $110K *
Champion client success by leading complex implementations, managing risks, and ensuring operational readiness. Collaborate with executive stakeholders to deliver projects on time while maintaining hi...
Reposted 1 week ago
Director, Technical Program Management (Remote-Eligible)
$209K - $239K *
Drive major technical transformations by leading cross-functional programs that align technology with business goals, ensuring a scalable and efficient delivery of innovative platforms and products fo...
Reposted yesterday
Project Manager (Data Projects)
$120K - $125K *
Transform data analytics initiatives by leading multiple projects, engaging stakeholders, and driving solutions from inception to delivery. Collaborate with technical teams to ensure alignment with mi...
6 days ago
Program Manager, Global Strategic Accounts
$130K - $160K *
Drive program success by coordinating cross-functional teams, managing reporting, and optimizing engagement strategies for a global enterprise account, ensuring alignment with client goals and employe...
2 weeks ago
$148K - $193K *
Join a dynamic team as a Program Manager, leading complex projects from inception to completion. Collaborate with diverse stakeholders, manage resources, and drive innovation while ensuring client sat...
2 weeks ago
Program Manager, Data Center and AI
$117K - $147K *
Empower multi-site data center and AI infrastructure programs valued at $25M+, leading diverse teams to ensure successful delivery, budget management, and customer satisfaction while driving executive...
Today
Director Product Management - Care Coordination
$135K - $160K *
Lead the charge in building innovative care coordination products, driving strategy and execution across provider and payer segments. Collaborate cross-functionally to ensure alignment and deliver imp...
1 week ago
Senior Project Manager, Marketing PMO
$110K - $130K *
Lead complex, cross-functional marketing initiatives from planning to execution, driving accountability and collaboration across teams while enhancing project management processes and methodologies fo...
1 week ago
$101K - $112K *
Lead the charge in managing complex projects within the Education portfolio, ensuring effective coordination across teams and stakeholders while driving impactful outcomes in higher education and appl...
2 days ago
$155K - $210K *
Lead complex programs and strategic client engagements, driving technology transformation and sustainable business value. Act as a trusted adviser to C-level stakeholders, shaping program vision and e...
2 weeks ago
$110K - $130K *
Join a dynamic team to lead and manage multiple large-scale projects, collaborating with diverse stakeholders to deliver innovative software solutions in a global legal environment. Drive project succ...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.