Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$145K - $188K *

Elevate delivery excellence by shaping strategies for Portfolio Management, ensuring seamless execution across teams while adapting to evolving technologies and processes. Lead the charge in establish...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Drive the strategic vision and execution for our cybersecurity portfolio, leading product management and cross-functional initiatives to accelerate growth and enhance customer success in a dynamic mar...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Shape strategic initiatives by leading cross-functional projects, ensuring alignment with organizational goals. Utilize structured project management to drive efficiency, stakeholder engagement, and m...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$130K - $170K *

Shape the future of capital projects by leading multi-discipline teams to deliver complex design packages, ensuring quality and client satisfaction across diverse sectors including healthcare and gove...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$150K - $180K *

Lead the charge in global product commercialization, driving growth and innovation in infrastructure solutions. Collaborate with cross-functional teams to deliver market-leading offerings that meet cu...

Today

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$120K - $140K *

Architect effective HR strategies that transform operations and enhance talent growth across a multi-site workforce. Engage proactively in employee relations and compliance, ensuring seamless, equitab...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$155K - $175K *

Elevate your career by leading the development of a cutting-edge DCIM platform. Drive innovation in cloud-native architecture, manage global teams, and collaborate with stakeholders to optimize data c...

3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $145K *

Elevate sales effectiveness by developing a unified sales process and implementing a world-class CRM. Influence decision-making across business units to drive revenue growth and enhance operational ef...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Elevate your career by leading the strategy and delivery of a robust Salesforce ecosystem, driving business impact through innovative solutions and team development in a dynamic, global environment...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$156K - $195K *

Champion the global eDiscovery Technology practice, leading a diverse team to innovate AI-assisted workflows, ensuring defensibility and quality across jurisdictions while driving growth and operation...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$115K - $140K *

Engage as an experienced implementation leader managing complex client onboarding and execution of digital banking solutions. Collaborate across teams to drive project success, enhance operational eff...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $175K *

Transform investment research by evaluating and integrating diverse datasets, enhancing AI-driven workflows, and driving strategic content initiatives to elevate platform value and user experience...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$145K - $175K *

Join a team that's redefining AI-driven solutions by leading product development for an innovative tech concierge. Drive the evolution of agent capabilities, ensuring quality and reliability while col...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$145K - $160K *

Lead the charge in transforming member support by defining strategy, enhancing team performance, and integrating AI solutions. Drive operational excellence while fostering a culture of empathy and acc...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Optimize engagement and monetization strategies for an AI-driven product, transforming customer interactions into measurable growth. Lead cross-functional teams to innovate and implement effective use...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Transform enterprise risk management by leading critical audits and enhancing controls. Maintain relationships with external auditors and foster compliance initiatives to mitigate risk across all oper...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$215K - $235K *

Unlock the future of commercial operations by leading integrated pricing, contract negotiations, and deal management for a $250M ARR business. Drive redesign initiatives, optimize processes with AI, a...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $145K *

Grow your career with a dynamic team leading threat intelligence and detection engineering. Shape strategies to protect diverse industries from cyber threats, while building a high-impact program that...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Join a team that's driving growth in the biopharmaceutical sector by developing strategic business relationships, prospecting new clients, and leading sales initiatives to achieve organizational objec...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Accelerate your career by leading a dynamic sales team to drive IT security solutions. Collaborate with clients and partners to enhance sales strategies, mentor talent, and achieve regional objectives...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$118K - $130K *

Manage cross-functional programs to drive product innovation and execution. Build integrated plans, align stakeholders, and remove barriers to ensure timely delivery of high-priority initiatives while...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's shaping the future of insurance products by leading strategic initiatives and collaborating with cross-functional teams to deliver innovative solutions grounded in user feedback and...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $100K *

Transform project management by leading client-sponsored trials, coordinating multidisciplinary teams, and ensuring timely delivery of objectives while fostering collaboration and communication across...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Join a team that's dedicated to delivering exceptional project implementations and enhancements for restaurant brands. Lead cross-functional efforts, ensuring customer satisfaction while managing time...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.