Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$111K - $150K *

Transform product strategy and execution by leveraging data insights, leading cross-functional teams, and prioritizing customer needs to drive product success and business growth in a dynamic environm...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$127K - $150K *

Lead the charge in managing complex projects, ensuring client satisfaction through effective coordination, budget management, and team supervision while driving project success across all phases...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $218K *

Drive product innovation by managing a prioritized backlog, translating strategies into actionable requirements, and collaborating across teams to deliver impactful solutions that enhance organization...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $218K *

Advance your career by leading product management initiatives that drive innovation and enhance Human Capital solutions. Collaborate with cross-functional teams to translate strategies into actionable...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Lead healthcare project management initiatives, overseeing complex projects and guiding a team of professionals. Drive project feasibility, design direction, and client engagement while ensuring adher...

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Shape the future of revenue operations by leading cross-functional teams, optimizing processes, and driving strategic initiatives to enhance pipeline efficiency and forecasting accuracy in a dynamic e...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$108K - $201K *

Lead high-impact capital projects in pharmaceutical manufacturing, driving execution from concept to commissioning. Collaborate with cross-functional teams to deliver innovative engineering solutions...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $110K *

Drive business growth by identifying and qualifying federal procurement opportunities, focusing on healthcare contracts. Collaborate on capture strategies and build partnerships to enhance win probabi...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Shape the future of financial strategy by leading planning processes, collaborating with cross-functional teams, and delivering insights that drive investment decisions and organizational growth in a...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Accelerate your career as a Product Manager, driving strategy and lifecycle management across a hardware portfolio. Collaborate cross-functionally to innovate, optimize solutions, and ensure delivery...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$85K - $100K *

Contribute to the successful management of construction projects, ensuring timely completion, budget adherence, and strong relationships with stakeholders while leading and training project teams effe...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$179K - $220K *

Unlock potential by leading the Lattice MCP server strategy and integrations that enhance performance data interoperability within popular AI tools and external platforms, driving customer engagement...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$105K - $120K *

Join a dynamic team as you lead integrated media strategy and client relationships in programmatic advertising. Drive innovation, mentor talent, and collaborate cross-functionally to achieve strategic...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Drive the strategy and execution of third-party data integrations, enhancing Bridg's identity resolution across the marketing ecosystem. Collaborate with partners and internal teams to deliver impactf...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$168K - $253K *

Lead the North America SDS R&D project portfolio, ensuring alignment with global standards. Drive project management excellence, optimize execution, and facilitate strategic transformation initiatives...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join our team to enhance patient access and streamline operational processes, driving meaningful improvements through data analysis, project management, and collaboration across departments while fost...

North Carolina, USRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$116K - $160K *

Champion productivity by leading engineering projects that enhance manufacturing processes. Collaborate with cross-functional teams to define, scope, and execute initiatives from concept to implementa...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$116K - $139K *

Accelerate progress at the intersection of project delivery and client satisfaction. Lead technical teams in managing complex biologics and advanced therapy projects while fostering strong client rela...

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $195K *

Drive operational excellence and lead a high-performing team to deliver complex digital products. Collaborate with cross-functional teams to define strategies, manage resources, and ensure profitable...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive growth by shaping strategic partnerships and optimizing processes in a dynamic business development role. Collaborate with teams to enhance e-commerce performance, create lead generation strateg...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$115K - $130K *

Join a dynamic team as a Project Manager, leading cross-functional projects that drive customer panel integration and optimize processes. Collaborate with diverse teams to ensure timely deliverables a...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Manage integrated master schedules and coordinate cross-functional teams to ensure project alignment and timely deliverables. Proactively assess risks, facilitate client communications, and contribute...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a team that's driving project excellence by leading a diverse group of Project Managers. You'll optimize resources, enhance delivery outcomes, and foster high performance across critical VA initi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$103K - $181K *

Optimize document control processes by leading the Information Branch, ensuring accurate and accessible records management for a major industrial program while coordinating with various stakeholders a...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $120K *

Transform patient safety operations by leading a dedicated team, ensuring compliance, and enhancing pharmacovigilance processes. Collaborate cross-functionally to deliver high-quality safety services...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.