Discover Director of Operational Excellence opportunities on Ladders, where professionals can explore vetted jobs paying $100,000 or more. These senior leaders help organizations improve performance, streamline processes, and build a culture of continuous improvement. Roles span industries and may focus on enterprise transformation, quality, supply chain, manufacturing, healthcare, technology, or business operations.
A Director of Operational Excellence develops and leads initiatives that make an organization more effective, resilient, and customer-focused. Responsibilities often include identifying process gaps, setting improvement priorities, establishing performance measures, and partnering with executives and operational teams to deliver sustainable results. Depending on the employer, the role may oversee Lean, Six Sigma, change management, process design, or operational transformation programs.
Employers commonly look for strategic leadership, analytical problem-solving, change management, and the ability to influence across departments. Experience with continuous improvement methods such as Lean or Six Sigma, along with data analysis, project portfolio management, and KPI development, can be valuable. Many positions require a bachelor’s degree and substantial relevant experience; some prefer an advanced degree or professional certification.
Director of Operational Excellence roles are available in sectors where reliable, efficient processes are critical, including manufacturing, healthcare, financial services, logistics, retail, and technology. The scope varies: some directors lead improvement teams at a single site, while others shape operating models and transformation efforts across multiple business units or global organizations. Career paths may lead to vice president of operations, chief operating officer, or enterprise transformation leadership.
Use Ladders to explore vetted senior-level opportunities with salaries of $100,000 or more. Compare roles by industry, location, and scope, and look for positions that match your experience in operational strategy, process improvement, and executive leadership.
Program Manager, Supply Chain Analytics
$190K - $240K *
Champion the modernization of global supply chain analytics by transforming data into actionable insights, driving AI-assisted workflows, and collaborating across teams to enhance decision-making and...
Today
Director, Commercial CMC Programs
$150K - $180K *
Empower the execution of CMC strategies by collaborating across teams to enhance production, streamline operations, and drive commercial success for innovative therapeutics and diagnostics, ensuring a...
Reposted today
Director, Biometrics Strategy and Business Development
$125K - $150K *
Drive revenue growth and strategic partnerships in biometrics services, focusing on client relationships and market strategy. Collaborate with teams to deliver innovative solutions and position the or...
1 week ago
Senior Manager, Storeroom Solutions
$110K - $130K *
Unlock potential by leading storeroom solutions projects, enhancing service quality, and driving strategic initiatives across multiple customer engagements in manufacturing environments...
1 week ago
Director, Commercial CMC Programs
$150K - $180K *
Lead the charge in developing and executing CMC strategies to optimize manufacturing processes and commercial operations, ensuring alignment with project goals through effective collaboration across t...
Reposted today
Principal Design Program Manager, International Packaging
$120K - $145K *
Lead the charge in shaping global healthcare packaging design. As a Principal Design Program Manager, you'll establish frameworks and standards, drive strategic decisions, and ensure seamless collabor...
2 weeks ago
Senior Program Manager - Market Performance
$125K - $181K *
Lead the charge in enhancing market and provider performance through strategic initiatives, project management, and cross-functional collaboration, ensuring operational excellence and improved member...
2 weeks ago
Sr. Lead Brand Marketing Partnership
$140K - $180K *
Lead the charge in developing innovative brand partnerships, driving activation strategies, and enhancing brand visibility through cross-functional collaboration and strategic leadership while focusin...
4 weeks ago
Senior Director Product Management
$172K - $287K *
Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...
Reposted 4 days ago
$110K - $130K *
Champion the development of scalable product operations, enhancing processes and analytics to empower cross-functional teams. Collaborate closely with stakeholders to drive product initiatives and imp...
1 week ago
$80K - $95K *
Elevate your career as a Document Control Supervisor, overseeing site access agreements and collaborating with environmental consulting teams. Utilize your expertise to resolve access needs, manage do...
1 week ago
$80K - $95K *
Champion effective document control by overseeing site access agreements, resolving access issues, and coordinating with environmental consulting teams. Lead a team while ensuring compliance and effic...
1 week ago
Senior Manager, Stop-Loss Risk and Proposals
$110K - $130K *
Take ownership of the sales process for self-funded stop-loss cases, evaluating risk, managing proposals, and collaborating with underwriters to enhance case preparation and market success...
1 week ago
Director, Workforce Management
$161K - $210K *
Elevate workforce management by leading recruitment, onboarding, and performance strategies. Drive clinician readiness and productivity while ensuring quality care through data-driven decision-making...
Yesterday
Senior Manager, RCM Optimization & Strategy
$130K - $145K *
Elevate revenue cycle management by analyzing workflows, optimizing processes, and driving strategic improvements. Collaborate across teams to enhance billing accuracy and maximize collections in a fu...
2 weeks ago
Senior Director, Sales Enablement
$175K - $210K *
Transform the sales enablement landscape by leading strategic initiatives that empower teams, enhance training, and drive growth in a dynamic marketplace. Collaborate cross-functionally to ensure ever...
1 week ago
Director, Engineering, Data, and AI
$150K - $180K *
Drive operational excellence by leading engineering, data, and AI teams. Collaborate with stakeholders to translate strategic goals into actionable plans, ensuring high-quality project delivery and te...
Today
$275K - $325K *
Lead the charge in building and managing a construction banking sector, driving strategy, partnerships, and product development while overseeing P&L and fostering key relationships to establish Flex a...
6 days ago
$125K - $155K *
Innovate product strategy and execution, bridging cross-functional teams to deliver impactful solutions that align with customer needs and organizational goals throughout the product lifecycle...
1 week ago
$135K - $160K *
Join us in providing strategic financial leadership to enhance planning, forecasting, and performance management. Collaborate with executives to translate business strategies into actionable financial...
Today
$188K - $245K *
Empower innovation by leading a UX design team focused on clinical workflows. Collaborate across functions, drive strategic direction, and enhance AI integration while advancing design quality in heal...
3 weeks ago
$150K - $180K *
Elevate organizational impact by driving strategic initiatives and fostering cross-functional alignment. Collaborate with global teams to ensure seamless execution of key projects while enhancing comp...
Today
$186K - $250K *
Unlock potential by leading a high-performing HEOR team to drive payer engagement and market access strategies, translating complex data into actionable insights that enhance patient access to innovat...
2 weeks ago
Sr. Strategic Alliance Manager
$150K - $225K *
Engage with us to drive strategic alliances, enhance partnerships, and execute joint initiatives that foster revenue growth and market presence. Collaborate across teams to position solutions effectiv...
1 week ago
Senior Analyst, Process Improvement
$70K - $130K *
Transform operational efficiency by leading process improvement initiatives, analyzing performance metrics, and collaborating with cross-functional teams to implement sustainable solutions that align...
1 week ago
What does a Director of Operational Excellence do?
A Director of Operational Excellence leads initiatives to improve organizational performance, processes, quality, and efficiency. The role often includes setting improvement strategy, tracking KPIs, guiding transformation projects, and helping teams adopt sustainable ways of working.
What qualifications are commonly required for Director of Operational Excellence jobs?
Employers often seek a bachelor’s degree, extensive experience in operations or continuous improvement, and a record of leading cross-functional change. Lean or Six Sigma expertise, data analysis skills, and an advanced degree or relevant certification may be preferred.
How much do Director of Operational Excellence jobs pay?
Compensation varies by industry, location, company size, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, including senior operational excellence opportunities.
Which industries hire Directors of Operational Excellence?
Manufacturing, healthcare, logistics, financial services, retail, technology, and other industries hire these leaders to improve processes, manage transformation, and strengthen operational performance.
What career paths can follow this role?
Experienced Directors of Operational Excellence may advance to vice president of operations, chief operating officer, enterprise transformation executive, or other senior leadership positions.