Director, Information Systems Jobs on Ladders

Are you looking for high-paying Director of Information Systems jobs? You've come to the right place. We host a wide range of jobs in this category that pay $100K or more.

Job Description and Role

Directors of Information Systems oversee an organization's IT strategy and ensure that systems, infrastructures, and networks operate smoothly.

Qualifications and Skills

Typical qualifications include a bachelor's or master's degree in IT or related fields and several years of experience.

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$120K - $160K *

Unlock potential by designing advanced data architectures that enable agentic systems. Collaborate across teams to enhance data flow, governance, and retrieval methods in a dynamic environment focused...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Advance operational technology systems for data center infrastructure, ensuring reliability, security, and scalability while collaborating cross-functionally to optimize processes and compliance withi...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$111K - $150K *

Shape the future of asset management by leading best practices, ensuring accountability, and conducting audits while managing property control processes to support contract requirements and efficiency...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Drive strategic initiatives as Chief of Staff, enabling the AI & DT&A Practice Leader to excel while ensuring operational consistency and organizational clarity in a fast-paced, innovation-focused env...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Unlock your potential as a strategic leader driving clinical excellence and operational efficiency in hospital medicine programs. Collaborate with cross-functional teams to enhance patient outcomes an...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Lead the strategic direction for development operations and volunteer engagement, overseeing impactful fundraising events, optimizing budgets, and enhancing volunteer experiences to drive community co...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Champion enterprise sales by driving, managing, and closing new client relationships within the financial services industry, leveraging strong sales skills and industry knowledge to expand business op...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Transform healthcare sales by leading strategic initiatives across major US health systems. Drive results through consultative selling, tailored business cases, and robust consensus building with C-su...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Drive the optimization of global Deal Desk operations, enhancing efficiency and scalability. Collaborate with cross-functional teams to streamline processes, implement AI solutions, and ensure robust...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$87K - $157K *

Manage complex projects by leading cross-functional teams, ensuring alignment with strategic objectives, maintaining documentation, and effectively communicating with stakeholders to achieve quality d...

US-AnywhereRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

$97K - $146K *

Take ownership of the Healthy Planet application, guiding design, governance, and strategic direction. Collaborate across Epic platforms, lead initiatives, and ensure alignment with best practices to...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Unlock your potential as you own the financial performance of a dynamic business unit, driving strategic decisions and enhancing visibility to shape impactful processes and outcomes. Join a hands-on l...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Optimize AI security by assessing vulnerabilities, crafting defenses, and collaborating across teams to embed security in AI systems, ensuring safe, responsible deployment in a fast-paced healthcare e...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Contribute to AI governance by operationalizing risk controls, managing vendor risks, and leading threat modeling for AI/ML systems. Collaborate across teams to ensure compliance and enhance security...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$154K - $278K *

Pioneer innovative solutions by leading technology deployment to enhance operational value. Collaborate across teams to identify opportunities, develop working solutions, and ensure successful transit...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Energy & Utilities

$150K - $180K *

Unlock your potential as a key strategist, bridging Zencore's sales and Google Cloud's enterprise teams. Drive co-sell revenue, enhance brand visibility, and secure vital program access in a fast-pace...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $231K *

Join a team that's dedicated to enhancing coding quality and compliance through strategic leadership, oversight, and innovative solutions, ensuring adherence to regulatory standards and driving organi...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Accelerate business growth by leading new financing initiatives and strategic acquisitions across a defined U.S. territory, while building lasting relationships with independent owners to create impac...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$112K - $125K *

Unlock potential by managing equipment logistics and support activities across diverse environments, ensuring operational readiness through precise inventory control and effective communication with t...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$207K - $392K *

Lead the charge in defining and executing strategic enterprise integration initiatives that modernize core platforms, improve operational transparency, and drive agility across the organization, foste...

US-AnywhereRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$94K - $148K *

Transform healthcare negotiations by leading payer strategies and optimizing population health incentives. Engage cross-functionally to craft innovative solutions and manage complex relationships nati...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join a team that's redefining marketing operations by leading project management, integrating AI, and enhancing workflows. Drive cross-functional collaboration and streamline processes to support inno...

US-AnywhereRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Transform client marketing strategies by leading interdisciplinary teams, delivering innovative solutions based on research and best practices, while fostering long-lasting client relationships to ach...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $260K *

Build strong AI sales strategies that drive revenue growth, foster relationships with key partners, and engage field sales teams while delivering exceptional AI infrastructure solutions across diverse...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$204K - $379K *

Drive operational excellence by leading NOCC transitions, enhancing scalability, governance, and productivity through strategic integration of global teams and innovative frameworks that optimize reso...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Director, Information Systems?question toggle

    A Director of Information Systems is responsible for overseeing the IT strategy of an organization, ensuring systems, infrastructures, and networks operate smoothly.

  • What qualifications do I need to be a Director, Information Systems?question toggle

    Typical qualifications include a bachelor's or master's degree in IT or related fields and several years of experience.

  • What jobs are available on Ladders for Directors, Information Systems?question toggle

    Ladders hosts a wide range of high-paying jobs for Directors of Information Systems. All jobs listed pay $100K or more per year.