Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$180K - $220K *

Unlock potential by leading clinical services as a Medical Director, ensuring quality healthcare delivery in a correctional setting. Collaborate with staff and community providers to enhance patient c...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join us in leading operational excellence across departments, driving strategic goals, and enhancing clinical practices. You'll manage teams, implement innovative solutions, and ensure compliance whil...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $110K *

Lead a dedicated team in delivering exceptional patient care while managing clinic operations, growth, and community relationships. Empower your career in a supportive environment focused on mentorshi...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion operational excellence by leading production processes, ensuring compliance, and driving strategic initiatives. Collaborate cross-functionally to enhance performance, develop future leaders...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$215K - $408K *

Transform healthcare delivery by leading medical management and quality initiatives. Collaborate with clinical teams to enhance patient outcomes and drive cost-effective care while ensuring compliance...

Missouri, USRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Lead and inspire multidisciplinary clinical teams to enhance patient care, ensure regulatory compliance, and implement evidence-based treatment programs. Drive quality outcomes and foster a culture of...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Advance your career by leading impactful clinical services, overseeing multidisciplinary teams, and driving evidence-based practices. Shape exceptional patient care and operational success at a renown...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Champion high standards of clinical excellence by leading program development, ensuring patient-centered care, and fostering a culture of accountability. Collaborate with teams to optimize outcomes an...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Lead and inspire a clinical team delivering exceptional behavioral healthcare. Drive program development, ensure quality patient outcomes, and foster a culture of compassionate care while navigating r...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$194K - $291K *

Lead strategic initiatives in developing and executing companion diagnostic assays, ensuring integration into oncology programs while maintaining compliance and quality standards. Collaborate cross-fu...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$194K - $291K *

Lead the strategic and operational execution of companion diagnostic projects in oncology, ensuring alignment with clinical development and regulatory standards while driving cross-functional collabor...

Princeton, NJRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform patient care services by leading a dedicated team, ensuring high-quality outcomes, and fostering collaboration across departments to enhance operational efficiency and patient experience...

Today

  •   Less than 5 years exp.  •   Healthcare

$84K *

Join a team that's dedicated to supporting mental health consumers in transitioning from hospital to community living. Oversee clinical operations, enhance team collaboration, and foster a compassiona...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in delivering quality patient-centered care as the Medical Director for a new primary care clinic, overseeing clinical operations, education, and resident supervision in a collaborativ...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Join us to oversee daily operations of multiple clinics, ensuring efficient service delivery and excellent patient care. Collaborate with management and staff to optimize strategies and maintain compl...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$298K - $350K *

Lead the charge in medical safety leadership for therapeutic areas, overseeing clinical development and post-marketing activities. Collaborate cross-functionally to ensure effective safety strategies...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Execute regulatory strategy and compliance for a life sciences platform. Collaborate across departments to ensure adherence to medical review processes and support enterprise sales by establishing med...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Support clinical staff through technical expertise in cellular therapeutics, ensuring effective patient enrollment and procedure management. Collaborate in training, maintain compliance, and foster re...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Transform healthcare delivery by leading clinical operations, ensuring high-quality patient care, and fostering collaboration across departments. Drive strategic initiatives while managing resources a...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Champion operational excellence by leading Field Services activities, ensuring safety, compliance, and quality across multiple sites. Drive strategic initiatives, manage teams, and foster client relat...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Drive operational excellence by leading compliance and safety initiatives across multiple sites. Collaborate with teams to enhance productivity, manage budgets, and foster strong client relationships...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Lead regional Field Services operations, ensuring safety, compliance, and quality. Oversee Area Compliance Managers, manage budgets, and foster customer relationships to drive productivity and profita...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Champion operational excellence by leading Field Services activities, ensuring safety, compliance, and quality across multiple sites. Drive strategic initiatives, manage budgets, and foster strong cli...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Lead and inspire a team to ensure safety, compliance, and operational excellence across multiple sites. Drive strategic initiatives, manage budgets, and foster strong client relationships while overse...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$284K - $385K *

Join a team that's shaping clinical strategies for groundbreaking genetic medicines, overseeing cross-functional studies from First in Human to Phase 3. Collaborate with experts to ensure scientific i...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.