Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$120K - $160K *

Reimagine backend systems as you lead the development of high-performance infrastructures for autonomous agents in financial software, ensuring speed and reliability for real-time trading environments...

US-AnywhereRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$121K - $182K *

Advance your career by leading the design and execution of secure collaboration solutions across the Microsoft cloud. This role offers strategic influence, project direction, and high-impact decision...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $130K *

Empower healthcare outcomes by leading data science initiatives using advanced machine learning techniques. Collaborate with teams, mentor junior scientists, and drive innovation through actionable in...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $95K *

Elevate your career by owning projects that connect system components, drive technical execution, and foster skill development within a collaborative team, while enhancing quality and addressing chall...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$192K - $302K *

Shape AI solutions by leading a high-performing engineering team, driving innovation in large language models, and collaborating on impactful projects that utilize advanced AI technologies to enhance...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$101K - $138K *

Drive actionable insights through advanced analytics, transforming workforce understanding and decision-making at an organizational level while leveraging AI technologies for predictive and prescripti...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $130K *

Champion innovation by developing AI solutions that drive business outcomes. Collaborate with cross-functional teams to design, integrate, and optimize AI models in scalable environments, ensuring rel...

US-AnywhereIn-Person

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $229K *

Unlock potential by driving advanced finance transformation solutions through analytics, AI, and automation. Collaborate with teams to design and implement cross-functional strategies that enhance fin...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $170K *

Join a team that's redefining AI strategies across multiple domains, leading the implementation of measurable and reliable AI capabilities that drive business value and efficiency throughout the organ...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $150K *

Elevate your career with a dynamic data science role, driving actionable insights from complex datasets. Collaborate across teams to enhance our data-driven investment strategies through impactful ana...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$175K - $216K *

Empower your career by leading the design and development of user-centric frontends for our AI platform, enabling seamless integration and interaction across enterprise applications...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$120K - $150K *

Drive the growth and direction of cross-functional engineering teams, guiding talent to achieve ambitious goals while ensuring robust data architecture and infrastructure, all in a collaborative, incl...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$70K - $95K *

Accelerate progress at the forefront of strategic initiatives, driving analytical insights that support leadership decisions. Collaborate across teams to identify challenges, develop strategies, and i...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$55K - $146K *

Drive fraud mitigation strategies by analyzing data trends and anomalies. Collaborate with cross-functional teams to develop reporting tools and metrics, enhancing fraud detection in financial product...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $110K *

Take ownership of technology-driven initiatives to enhance our investment management data solutions. Collaborate with teams to improve scalability and efficiency, while ensuring alignment of new techn...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$155K - $306K *

Unlock potential by leading innovative AI projects, mentoring a talented team, and developing data-driven solutions that enhance client outcomes in diverse domains, while maintaining technical vision...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $306K *

Shape the future of AI as a leader in a dynamic team, guiding innovative data science initiatives and driving client-specific strategies while managing a team dedicated to cutting-edge solutions in te...

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $120K *

Unlock the potential of data by designing and managing SQL databases, crafting ELT/ETL pipelines, and facilitating analytics with Power BI. Collaborate with teams to deliver reliable datasets and scal...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$117K - $201K *

Advance your career as a Principal Data Scientist, driving innovation by standardizing and connecting vital biomedical data, enhancing analytics and AI applications in Immunology R&D. Collaborate with...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K - $253K *

Join us to innovate the future of grocery delivery through advanced Machine Learning, enhancing personalization and ranking across a diverse marketplace while collaborating with top talent to drive su...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$145K - $170K *

Drive data conversion and reporting initiatives for Workday HCM and Financials. Oversee complete data lifecycle, lead report design, and collaborate with teams to ensure deliverables meet quality stan...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$175K - $225K *

Transform the logistics landscape by architecting data integrations for the U.S. military. Lead complex system-of-systems projects, ensuring smooth data flow across environments while guiding a skille...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$134K - $181K *

Engineer innovative machine learning solutions in a collaborative team, shaping the future of therapeutic protein design and enhancing drug discovery through advanced computational techniques and real...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Advance data-driven decisions by designing and optimizing scalable data platforms. Lead architectural direction, create reusable frameworks, and empower teams through self-service solutions that remov...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$180K - $210K *

Lead the charge in enterprise-wide data initiatives, ensuring project success and strategic alignment. Drive data integration, governance, and quality, empowering teams to turn data into valuable asse...

US-AnywhereRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.