Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$164K - $229K *

The New Ad Formats team at Reddit is seeking a skilled full stack engineer to build innovative ad experiences and enhance ad performance on the platform. This role involves collaborating with product...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$90K - $120K *

Unlock potential by supporting cross-functional teams with financial modeling and data analytics. Directly impact strategic decisions and M&A initiatives through insights, dashboards, and advanced rep...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$140K - $191K *

Lead statistical programming efforts for clinical data analysis, ensuring adherence to best practices and regulatory requirements. Collaborate with cross-functional teams and mentor junior programmers...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Join a team that's driving innovation by designing and deploying intelligent AI workflows to enhance clinical data extraction, ensuring reliability and efficiency for transformative healthcare solutio...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$140K - $200K *

Discover new data sources and optimize cloud infrastructure while collaborating with scientists. Join a dynamic AI team focused on building high-quality datasets at scale to enhance next-generation mo...

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Unlock potential by leading the development and support of Business Intelligence Analytics solutions, enhancing organizational efficiency through innovative data representation and reporting tools tha...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$145K - $175K *

Unlock potential by leading performance measurement strategy to enhance client engagement. Spearhead analytics initiatives, integrating data and technology for impactful insights, while mentoring a hi...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$55K - $179K *

Help us innovate as a Python Developer Lead, designing software solutions, optimizing data pipelines, and collaborating in a fast-paced Agile environment to enhance our Model Integration Platform for...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $269K *

Pioneer a transformative role in Business Intelligence, enhancing data infrastructure and analytics across the organization while guiding cross-functional initiatives and mentoring teams to support st...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $160K *

Support the development of cutting-edge machine learning models, leveraging hands-on expertise in model design and deployment while mentoring teams and engaging stakeholders to drive innovation and op...

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $130K *

Help us design and build cutting-edge multi-agent AI systems, enhance agentic capabilities, and ensure reliable execution and planning across complex tasks to transform operations in various sectors...

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $120K *

Shape the future of healthcare analytics by transforming data into impactful insights. As a vital partner to external stakeholders, you will create reporting systems that enhance collaborative strateg...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Champion data-driven insights by developing impactful AI systems that enhance healthcare reimbursement workflows, driving measurable business results through innovative applied engineering and collabo...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $180K *

Drive the design and execution of robust production GenAI systems that enhance automation, deliver reliable performance, and support real user interactions through end-to-end ownership while ensuring...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $160K *

Join a team that's redefining the future by leveraging cutting-edge AI to develop innovative machine learning solutions that solve complex business challenges, and actively collaborating across multid...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$79K - $131K *

Shape customer experience strategy through analytical insights, empowering teams to drive impactful improvements across multiple domains while presenting findings to senior leaders for informed decisi...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$189K - $372K *

Transform healthcare decisioning by designing, training, and evaluating leading reasoning models. Collaborate with experts across the post-training lifecycle to ensure safe and effective AI solutions...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$189K - $372K *

Join a team that's redefining healthcare decision-making through advanced model training and alignment, driving innovation and reliability across the healthcare industry with cutting-edge AI systems a...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$253K - $354K *

Champion the development of advanced large-scale machine learning systems. Lead the technical vision, drive innovation in model design, and enhance user personalization across platforms. Mentor engine...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

$165K - $200K *

Join our infrastructure team to enhance our cloud architecture, ensuring secure, scalable, and reliable systems that power groundbreaking AI projects. Collaborate cross-functionally in a dynamic start...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $130K *

Lead the charge in developing and deploying analytical models to drive automation and enhance decision-making by collaborating with digital product teams and stakeholders. Explore new technologies whi...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $130K *

Advance your career by designing and maintaining cloud infrastructure, enhancing reliability and performance while collaborating with engineering teams to drive automation and operational efficiency i...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$198K - $287K *

Unlock potential by owning AI-powered features end-to-end. Collaborate across product, design, and engineering while prioritizing development, quality, and maintenance, effectively troubleshooting and...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$189K - $372K *

Serve as a senior engineering leader, directing innovative GenAI solutions while building trusted client relationships. Lead teams to navigate complexities, ensuring high-quality delivery and strategi...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$189K - $372K *

Transform client outcomes by leading engineering teams to deploy cutting-edge GenAI solutions, ensuring top-notch technical direction and fostering strong client relationships. Leverage hands-on exper...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.