Clinical Trial Managers oversee the planning and execution of clinical studies, helping ensure trials meet scientific, operational, regulatory, and ethical requirements. They coordinate cross-functional teams, manage timelines and budgets, and monitor progress from study startup through closeout. Explore vetted Clinical Trial Manager opportunities with compensation of $100,000 or more on Ladders.
Responsibilities vary by employer and study, but commonly include developing trial plans, coordinating clinical research organizations and sites, tracking enrollment and milestones, managing study budgets, and identifying operational risks. Clinical Trial Managers also support compliance with protocols, Good Clinical Practice (GCP), and applicable regulatory requirements, while communicating updates to sponsors, investigators, and internal stakeholders.
Employers often seek experience in clinical research or trial operations, strong project management and communication skills, and the ability to manage multiple priorities. Familiarity with GCP, clinical trial regulations, study documentation, and systems such as electronic data capture platforms can be valuable. A degree in life sciences, nursing, public health, or a related field is common; some positions may prefer advanced education or relevant certifications.
Clinical Trial Managers work for pharmaceutical and biotechnology companies, contract research organizations, academic medical centers, and other research organizations. Opportunities may focus on a therapeutic area, phase of development, or regional portfolio. With experience, professionals may advance to senior trial management, clinical operations leadership, or program management roles.
Search Ladders for Clinical Trial Manager jobs and related clinical operations opportunities. Compare roles by responsibilities, experience requirements, work arrangement, and compensation to find positions that align with your career goals.
Senior Clinical Research Associate
$100K - $120K *
Lead clinical trial monitoring efforts, ensuring compliance with protocols and regulations while fostering collaboration across teams to enhance data integrity and site performance...
1 week ago
Principal Manager, Clinical Operations Lead
$165K - $180K *
Oversee and optimize US regional clinical trials, ensuring execution and compliance. Collaborate with cross-functional teams and manage vendor relationships while driving process improvements in a fas...
Reposted 1 week ago
Regulatory Strategy Senior Associate
$95K - $115K *
Champion regulatory strategy initiatives to advance patient treatments. Collaborate with cross-functional teams to develop regulatory pathways, support agency engagement, and ensure compliance, all wh...
2 weeks ago
Project Manager- CARDIOVASCULAR (US/CANADA)
$112K - $222K *
Shape your career by leading clinical project management for global trials. Drive cross-functional collaboration, ensure compliance, and meet project deliverables while fostering effective teamwork an...
Reposted 1 week ago
$69K - $101K *
Unlock potential by delivering comprehensive clinical care management services, enhancing health outcomes for diverse populations through assessment, care planning, and coordination across multiple he...
1 week ago
$90K - $117K *
Elevate your career by leading SDTM programming activities, ensuring quality deliverables, and collaborating cross-functionally to optimize clinical data transformation in a dynamic environment...
4 days ago
Supervisor, Program Management
$80K - $95K *
Join a team that's dedicated to operational excellence and employee development. As a Supervisor, you'll lead daily operations, manage performance, and ensure compliance while fostering a collaborativ...
1 week ago
Senior Director, Operational Strategy - Oncology
$160K - $200K *
Lead the charge in developing competitive oncology strategies, ensuring client needs are met through collaboration and expertise. Drive business development and enhance client relations while overseei...
4 weeks ago
$136K - $181K *
Take ownership of CRA management by leading teams, developing metrics, and ensuring compliance with monitoring standards. Drive continuous improvement and optimize effectiveness across the Site Manage...
2 days ago
Director, Clinical Quality Assurance
$195K - $256K *
Elevate clinical quality assurance by designing and executing strategies for compliance, audit management, and oversight of global clinical operations. Collaborate with stakeholders to ensure adherenc...
1 week ago
Manager, Regulatory Operations (Remote)
$110K - $135K *
Accelerate progress at the forefront of regulatory operations, leading a dedicated team to ensure timely, compliant submissions and maintenance of Investigator Site Files, while driving process improv...
3 days ago
$110K - $130K *
Lead the charge in strategic program management, overseeing project delivery and team development. Drive successful outcomes through effective staffing, risk management, and stakeholder collaboration...
2 weeks ago
Senior Site Activation Manager (US)
$107K - $213K *
Oversee site activation projects, ensuring timely delivery, effective communication, and compliance with regulations. Lead cross-functional teams to meet goals and address challenges, driving strategi...
Reposted 1 week ago
Program Manager, Strategic Customer Delivery
$108K - $156K *
Join a dynamic team as you oversee complex software deployments, ensuring governance and stakeholder engagement across multiple sites. Drive successful outcomes for strategic customers while managing...
1 week ago
$80K - $95K *
Transform integration testing by collaborating with leads to ensure high-quality, validated solutions. Drive operational testing and develop strategies that meet clinical standards, enhancing client s...
1 week ago
$69K - $101K *
Grow your career with a dynamic team providing holistic clinical care management services. Collaborate with diverse populations to enhance health outcomes through assessment, care planning, and coordi...
2 days ago
Associate Director, Clinical Study Lead
$125K - $150K *
Unlock potential by providing operational leadership for global clinical studies, ensuring timely delivery, compliance, and quality. Collaborate with cross-functional teams and manage vendor relations...
2 weeks ago
Senior Contract Manager - Suppliers & Third Parties
$120K - $150K *
Empower stakeholders by leading the complete contracting lifecycle for strategic suppliers and partners. Collaborate cross-functionally to negotiate complex agreements, manage risks, and optimize cont...
Reposted 2 weeks ago
$80K - $95K *
Elevate clinical trial excellence by monitoring and analyzing complex data, ensuring compliance and patient safety while collaborating with investigators to drive innovative treatments forward...
Yesterday
$91K - $114K *
Drive clinical trial success by monitoring and analyzing data, ensuring compliance and patient safety while collaborating with site staff to advance innovative treatments and therapies...
2 days ago
$91K - $114K *
Transform clinical trials by conducting site visits, ensuring compliance, and collaborating with teams to enhance patient safety and data integrity, while contributing to innovative treatments and the...
2 days ago
$122K *
Champion clinical excellence by leading large teams, ensuring strategic alignment, and driving patient recruitment while mitigating risks in clinical operations for successful study execution...
1 week ago
Project Leadership - Biotech (clinical trials) -Neurology/Psych/Rare Disease - Home Based
$110K - $130K *
Join a team that's dedicated to advancing global studies in Neurology, Psych, and Rare Disease. Lead project teams, manage operations, and ensure timely delivery to exceed client expectations while ac...
Reposted 1 week ago
Senior Medical Director, Medical Affairs - Rheumatology (US)
$175K - $348K *
Transform clinical research through expert medical management and support. Collaborate with teams to ensure protocol integrity, provide training, and contribute to business development while maintaini...
Reposted 1 week ago
Senior Director, Program Management, Regulatory Affairs
$160K - $190K *
Transform regulatory strategies by leading cross-functional teams to ensure timely submissions and compliance for our innovative gene therapy pipeline, driving excellence in pediatric neurodegenerativ...
4 days ago
What does a Clinical Trial Manager do?
A Clinical Trial Manager plans and coordinates clinical studies, overseeing timelines, budgets, vendors, research sites, study teams, and operational compliance from startup through closeout.
What qualifications are typically required for Clinical Trial Manager jobs?
Many roles require clinical research or trial operations experience, project management skills, and knowledge of GCP and relevant regulations. Employers commonly seek a degree in life sciences, nursing, public health, or a related area.
Where do Clinical Trial Managers work?
They work at pharmaceutical and biotechnology companies, contract research organizations, academic medical centers, and other organizations that sponsor or conduct clinical research.
How can I find Clinical Trial Manager jobs paying $100,000 or more?
Browse vetted Clinical Trial Manager openings on Ladders, where listed opportunities pay $100,000 or more. Review each posting for compensation details, qualifications, and work arrangement.