Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$60K - $129K *

Join a team that's dedicated to enhancing member care through comprehensive assessments, crisis intervention, and collaborative planning. Utilize your clinical expertise to support optimal health outc...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Transform healthcare billing by leading a dedicated Hospital Billing Claims team, enhancing claims accuracy, regulatory compliance, and team performance while collaborating with partners to deliver op...

Pittsburgh, PARemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Lead the charge in optimizing hospital billing processes by guiding a skilled claims team. Drive improvements in claims management, regulatory updates, and collaboration with professional billing to e...

Pittsburgh, PARemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$130K - $140K *

Accelerate the growth of colorectal cancer screening solutions by engaging healthcare providers and driving product adoption. Collaborate with partners while strategically planning to maximize market...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$79K - $105K *

Elevate patient care by joining a dedicated team of Licensed Therapists. Collaborate in a supportive environment, utilizing the latest technology to enhance clinical excellence and work-life balance w...

Washington, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Drive customer success by leading strategic transformations and fostering C-suite relationships. Leverage ServiceNow expertise to enhance satisfaction, retention, and value delivery across complex, mu...

Addison, TXRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$87K - $119K *

Transform the landscape of fraud detection by leading a skilled SIU team. Oversee investigations, collaborate with law enforcement, and ensure compliance while mentoring staff to uphold integrity in h...

Newark, NJRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Drive impactful change by optimizing product operations through collaborative process design, ensuring alignment and efficiency while fostering innovation and simplification across complex product tea...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$200K *

Drive your career by leading technical architecture and AI tooling development in a dynamic company transitioning to multi-platform solutions. Collaborate with teams, mentor talent, and engage with en...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Transform healthcare operations by optimizing Epic HB applications, ensuring seamless billing workflows, and providing expert support. Collaborate with stakeholders to enhance system functionality and...

Miami, FLRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $220K *

Transform the future of care navigation by leading clinical evaluations and developing protocols in a telehealth setting, guiding team efforts to ensure high-quality, patient-centered care for complex...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $100K *

Empower quality care by managing and evaluating behavioral health service requests, utilizing critical judgment in decision-making. Collaborate with multidisciplinary teams to enhance service delivery...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Drive your career with a dynamic role that bridges physician candidates and clients. Enhance recruitment strategies, foster relationships, and lead marketing initiatives in a supportive environment th...

Dallas, TXRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$500K+*

Join a dynamic team of teleradiologists providing flexible, remote diagnostic services. Enjoy competitive compensation, customizable schedules, and a supportive environment while delivering exceptiona...

Tennessee, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$171K - $236K *

Join a team that's driving strategic partnerships in oncology BioPharma. Leverage industry expertise to expand business opportunities, manage partner relationships, and contribute to innovative health...

Maryland, USRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$131K - $196K *

Architect and lead the commissioning process for cutting-edge liquid-cooled and AI factory deployments. Ensure rigorous testing and validation, providing independent assurance on performance and desig...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $148K *

Shape the future of healthcare by driving customer experience insights that influence product and business strategies. Collaborate with cross-functional teams to conduct impactful research and advocat...

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Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Join a dynamic team to provide clinical oversight and support to Advanced Practice Providers in a fully remote role, ensuring high-quality patient care and compliance with medical standards in South C...

Myrtle Beach, SCRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$107K - $166K *

Elevate healthcare engagement by connecting with providers through innovative tools, enhancing patient care and experiences. Collaborate with cross-functional teams to drive insights and strategic dec...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Empower the lives of older adults as a licensed clinical psychologist in a flexible, supportive, and collaborative telehealth environment. Enjoy autonomy while delivering evidence-based care and creat...

Oregon, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$198K - $268K *

Lead the global GMP/GDP audit organization, enhancing predictive compliance intelligence while mitigating risks through advanced analytics and effective audit strategies...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Elevate clinical trial management by leading Phase I-IV studies, ensuring timely, budget-compliant delivery while developing staff and enhancing processes. Collaborate with teams to meet sponsor expec...

Covington, KYRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Champion patient care by conducting telemedicine consultations, assessing wounds, and guiding treatment plans while supervising advanced practice providers to ensure high-quality outcomes and compassi...

South Carolina, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Champion talent development by optimizing organizational structure and driving performance. Collaborate with HR leaders to assess needs, design impactful interventions, measure outcomes, and enhance w...

Miami Lakes, FLRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $115K *

Explore a pivotal role in pharmacovigilance, ensuring regulatory compliance and safety management for cancer therapies. Collaborate with cross-functional teams to enhance drug safety processes and sup...

Princeton, NJRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.