Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$135K - $160K *

Lead the charge in enhancing executive effectiveness and strategic planning. Serve as a trusted advisor to senior leadership, coordinating cross-functional priorities and driving organizational alignm...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $110K *

Transform claims systems processes by managing complex projects and ensuring data integrity. Lead enhancements, mentor analysts, and support internal and external clients while optimizing claims adjud...

Franklin, TNRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Join a dynamic team to lead technical onboarding and project delivery for mid-market and enterprise clients. Drive team performance, manage escalations, and collaborate across departments to enhance c...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$177K - $295K *

Join us in leading strategic management of high-profile national health system accounts. Your expertise will drive long-term growth, customer satisfaction, and revenue targets while collaborating with...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$86K - $138K *

Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $235K *

Unlock potential by driving scientific excellence as a strategic partner, educating healthcare professionals on Immuno-Oncology and fostering relationships that support cancer therapeutic initiatives...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $162K *

Join a team that's dedicated to enhancing patient care through Comprehensive Medication Management, collaborating with healthcare providers to optimize chronic disease management and improve health ou...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$107K - $166K *

Lead the charge in enhancing healthcare provider engagement through innovative outreach strategies, utilizing digital tools and collaborative efforts to improve patient care and drive business success...

Vineland, NJRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Engage a dynamic team to drive sales growth by coordinating in-field activities, implementing strategic plans, and fostering collaboration to achieve targets while developing team capabilities and mar...

New London, CTRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Explore your potential as the Lead Account Strategy Partner, where you'll deliver insights from healthcare data, guide clients, and shape product strategy as a senior member of a growing team...

New York, NYRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Support clinical studies by assisting with scientific conduct, data reconciliation, and protocol management. Engage with stakeholders to ensure compliance and operational excellence across multiple st...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive clinical innovation by supporting the operational delivery of pivotal studies, collaborating cross-functionally, and ensuring compliance with industry standards. Play a key role in the medical m...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$112K - $193K *

Transform healthcare technology by leading product strategy and execution for a revenue integrity solution. Drive innovation, engage stakeholders, and optimize outcomes to enhance hospital operations...

Draper, UTRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$203K - $279K *

Drive strategic leadership for Medicaid utilization and care management. Lead development and execution of initiatives aimed at enhancing quality, access, and cost management while collaborating with...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$250K - $275K *

Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of cancer treatment by collaborating with experts to create individualized radiation therapy plans. Leverage advanced tools and techniques in a supportive, fully remote environment fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $157K *

Lead the charge in managing complex, large-scale programs and projects, ensuring strategic objectives are met through effective planning, execution, and cross-functional collaboration. Drive success b...

Missouri, USRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Shape the future of healthcare by driving customer success and engagement. As a key advisor, you'll enhance client relationships, advocate for their needs, and identify growth opportunities within a d...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's redefining client success! Lead and develop a dynamic group of 15-30 professionals while owning end-to-end department performance, delivering exceptional outcomes and driving organi...

CanadaRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$170K - $200K *

Drive portfolio strategy and execution by transforming market needs into profitable offers. Collaborate across teams to ensure alignment and operational readiness, enhancing sales confidence and optim...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Empower your career by leading a dynamic portfolio of affordable housing communities, driving team performance, operational excellence, and ensuring resident satisfaction. Shape the future of affordab...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$78K - $103K *

Join a dynamic team to perform complex coding reviews in Radiation Oncology. Leverage your expertise in CPT, HCPCS, and ICD-10 to resolve errors and ensure accurate billing. This remote role offers a...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Lead the charge in managing a skilled data engineering team, ensuring quality workflows and establishing data standards. Drive innovative solutions for efficient data ingestion and delivery across ent...

Harrisburg, PARemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Manage IT projects to implement M365 solutions for diverse clients, ensuring successful execution of project goals and fostering collaboration between teams...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$134K - $230K *

Elevate your career by leading product strategy and execution in risk adjustment. Collaborate with cross-functional teams to enhance operational excellence and customer satisfaction while driving inno...

Eden Prairie, MNRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.