Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$200K - $250K *

Contribute to the organization's success as a vital legal partner, managing multifaceted legal matters including contracts, compliance, and risk management while supporting dynamic business growth in...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive community engagement by building relationships with healthcare providers, educating them on enteral nutrition and respiratory services, and achieving market share goals through strategic sales i...

El Paso, TXRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $350K *

Champion clinical excellence by leading psychiatric care and operations. Engage with a dedicated team to enhance patient outcomes while supervising nurse practitioners and ensuring compliance with saf...

New York, NYRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $145K *

Empower hospital pharmacy teams to maximize ControlCheck and Diversion solutions. Leverage your clinical expertise to enhance workflows, deliver training, and drive analytics insights, ensuring effect...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $86K *

Lead workforce planning and operations for a 24/7 multi-channel contact center, ensuring effective staffing and service levels while optimizing systems in a dynamic remote environment. Foster collabor...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$108K - $184K *

Advance the Provider Network operations by overseeing strategic initiatives, ensuring compliance, and enhancing provider relationships across multiple lines of business. Lead cross-departmental effort...

Florida, USRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$77K - $92K *

Join a dynamic team as a Medical Writer, where you'll interpret complex clinical protocols and create essential documentation for clinical studies, ensuring high-quality standards and regulatory compl...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $184K *

Champion strategic initiatives in Provider Network Operations, overseeing key functions like Provider Relations and Credentialing. Drive performance and compliance across Medicaid, Medicare, and Comme...

North Carolina, USRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $300K *

Lead the charge in remote cardiovascular imaging interpretation, enhancing patient care through advanced cardiac CT and MRI expertise. Collaborate with a dynamic team while enjoying a flexible work en...

Texas, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Empower clinical research excellence by managing projects that ensure compliance with regulatory requirements and drive successful study delivery from initiation to closeout. Collaborate with interdis...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive customer success by managing relationships and ensuring product adoption. Collaborate with teams to mitigate risks, enhance customer experience, and create growth opportunities while mentoring p...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $95K *

Engage with cross-functional teams to create and refine technical documentation for VA Health Technology Management, ensuring clarity and quality for senior leadership and stakeholders...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Transform client relationships and drive growth strategies within HHS, leveraging market insights and technology to identify opportunities and enhance mission impact. Engage directly with stakeholders...

Washington, DCRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$104K - $163K *

Lead the charge in enhancing cybersecurity governance and risk management. Drive compliance initiatives, manage enterprise risk, and ensure robust security practices across all operations while collab...

Largo, FLRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $225K *

Drive the development of automated data systems, enhancing data quality and engineering workflows. Collaborate with teams to optimize data storage and performance, ensuring compliance and operational...

Columbus, GARemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$194K - $266K *

Champion patient engagement strategies by leading a dynamic team focused on optimizing recruitment and retention across clinical trials. Drive performance, enhance collaboration, and ensure successful...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Engage with healthcare clients to maximize value from innovative software solutions. Collaborate on onboarding, account health, and usage strategies to enhance customer satisfaction, adoption, and ret...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$181K - $224K *

Elevate global CMC regulatory strategies for commercial compounds. Collaborate cross-functionally to ensure compliance and timely submissions, while leading projects and maintaining expertise in regul...

Carlsbad, CARemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$146K - $178K *

Shape the future of biopharma by leading commercial strategy engagements, guiding clients through critical launch decisions, and delivering evidence-based recommendations to drive success in a dynamic...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Deliver innovative solutions by managing complex programs, ensuring seamless execution and coordination across multiple contracts while leveraging extensive IT expertise and leadership skills to drive...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $110K *

Unlock potential by leading donor relations to achieve philanthropic goals, fostering connections between the mission and stakeholders, and enhancing engagement to support the organization’s vision an...

Malvern, PARemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Elevate healthcare technology by leading the design and implementation of clinical applications. Collaborate with teams to optimize processes, manage projects, and enhance user experience while stayin...

Miami, FLRemote

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$255K - $310K *

Lead a high-performing team to execute market access strategies, optimize payer engagement, and enhance product positioning. Drive collaboration across stakeholders to ensure effective reimbursement a...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Reimagine talent acquisition by owning strategy, execution, and outcomes at an innovative healthcare tech leader. Lead recruitment to find exceptional talent, ensuring a transformative impact on patie...

San Francisco, CARemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$173K - $217K *

Unlock potential by driving high-quality statistical analyses and AI integration in the pharmaceutical sector. Collaborate across functions to enhance drug development and regulatory processes through...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.