Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$107K - $177K *

Champion the management of Hospital Professional Liability claims, ensuring effective strategies for resolution and compliance. Lead investigations, evaluate claims, and collaborate with legal teams t...

Maywood, ILRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$232K - $290K *

Optimize revenue generation by leading Sales and Revenue Operations, driving performance across customer-facing teams, and fostering a culture of excellence through strategic initiatives and cross-fun...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$104K *

Unlock potential by leading care coordination for patients with chronic diseases. Collaborate with an interdisciplinary team to provide comprehensive case management, ensuring optimal health outcomes...

Montebello, CARemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Transform intelligence analysis by leveraging your expertise and analytical skills. Collaborate with a dynamic team to support critical missions, utilizing advanced technology and methodologies to dri...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Transportation

$222K - $292K *

Elevate patient outcomes by leading global evidence strategies that showcase the value of therapies. Collaborate across functions to drive research programs, influence decision-making, and ensure scie...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $287K *

Contribute to companion diagnostic strategy and development, leading programs from biomarker feasibility to clinical validation. Collaborate across teams to ensure diagnostics align with therapeutic m...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$126K - $234K *

Elevate patient advocacy efforts by building strategic partnerships within Neuromuscular communities to enhance care and reduce access barriers, ensuring patient insights inform corporate strategy and...

East Hanover, NJRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$192K - $252K *

Champion digital transformation by optimizing medical technology solutions and enhancing HCP engagement strategies. Drive adoption and value realization of innovative tools across Field Medical teams...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$77K - $116K *

Join a dedicated team as a Telephonic RN Case Manager, providing vital support to seniors and complex care patients. Utilize your nursing expertise to navigate care journeys, create personalized plans...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $292K *

Join a team that's redefining identity operations by leading a 24/7 team to enhance access management strategies. You'll shape the vision, drive process innovation, and foster talent in a collaborativ...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$103K - $121K *

Champion project success by building pacing trackers and forecasting models, collaborating with Finance to enhance capacity planning and resource allocation, while providing leadership with real-time...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Drive the successful delivery of complex global clinical trials, overseeing cross-functional teams and ensuring compliance with GCP and regulatory standards while managing budgets and timelines to exc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$91K - $123K *

Elevate health services in remote communities by leading projects that assess and enhance regional health programs. Collaborate with First Nations to address unique challenges and drive impactful solu...

CanadaRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$500K+*

Join a team that's dedicated to patient-centered care while practicing in a supportive environment. As a Radiologist, you'll leverage your expertise in Nuclear Medicine and enjoy a flexible work model...

Rancho Cordova, CARemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$200K - $250K *

Contribute to the organization's success as a vital legal partner, managing multifaceted legal matters including contracts, compliance, and risk management while supporting dynamic business growth in...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive community engagement by building relationships with healthcare providers, educating them on enteral nutrition and respiratory services, and achieving market share goals through strategic sales i...

El Paso, TXRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$300K - $350K *

Champion clinical excellence by leading psychiatric care and operations. Engage with a dedicated team to enhance patient outcomes while supervising nurse practitioners and ensuring compliance with saf...

New York, NYRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $145K *

Empower hospital pharmacy teams to maximize ControlCheck and Diversion solutions. Leverage your clinical expertise to enhance workflows, deliver training, and drive analytics insights, ensuring effect...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $86K *

Lead workforce planning and operations for a 24/7 multi-channel contact center, ensuring effective staffing and service levels while optimizing systems in a dynamic remote environment. Foster collabor...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$108K - $184K *

Advance the Provider Network operations by overseeing strategic initiatives, ensuring compliance, and enhancing provider relationships across multiple lines of business. Lead cross-departmental effort...

Florida, USRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$77K - $92K *

Join a dynamic team as a Medical Writer, where you'll interpret complex clinical protocols and create essential documentation for clinical studies, ensuring high-quality standards and regulatory compl...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $184K *

Champion strategic initiatives in Provider Network Operations, overseeing key functions like Provider Relations and Credentialing. Drive performance and compliance across Medicaid, Medicare, and Comme...

North Carolina, USRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $300K *

Lead the charge in remote cardiovascular imaging interpretation, enhancing patient care through advanced cardiac CT and MRI expertise. Collaborate with a dynamic team while enjoying a flexible work en...

Texas, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Empower clinical research excellence by managing projects that ensure compliance with regulatory requirements and drive successful study delivery from initiation to closeout. Collaborate with interdis...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive customer success by managing relationships and ensuring product adoption. Collaborate with teams to mitigate risks, enhance customer experience, and create growth opportunities while mentoring p...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.