Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$100K - $120K *

Lead the charge in enhancing precision medicine access by collaborating with laboratories to optimize testing workflows and strengthen stakeholder relationships, ensuring patients receive the right tr...

Parsippany, NJRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $160K *

Accelerate progress at a dynamic tech firm by owning the full sales cycle for mid-market practices. Collaborate with leadership to shape strategy and drive impactful relationships, ensuring success in...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to enhancing health and wellness across communities. You'll lead clinical initiatives, ensure compliance, and drive quality improvements while collaborating with community...

Wilmington, DERemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $135K *

Join a team that's dedicated to advancing cancer therapies by leading global oncology clinical trials, managing cross-functional study teams, and ensuring high standards of study execution and complia...

Tennessee, USRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Lead the charge in advancing oncology research by managing global clinical trials. Utilize your expertise to ensure seamless operation, compliance, and timely delivery across diverse oncology studies...

Minnesota, USRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Drive global oncology clinical trials by managing operational execution and ensuring compliance with timelines and regulations. Collaborate with cross-functional teams to advance cancer research and d...

Oklahoma, USRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Join a dedicated team providing compassionate end-of-life care to patients. Manage caseloads, develop care plans, and ensure seamless communication among families and interdisciplinary teams while adh...

Sonora, CARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Engage your expertise to lead complex HL7 integrations across healthcare systems, enhancing interoperability and data-sharing capabilities. Collaborate with stakeholders to ensure successful implement...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$300K - $350K *

Join a team that's driving innovation in early clinical development. Lead cross-functional strategies and execution for a high-priority program, ensuring alignment and decision-making to advance a pot...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by providing in-home occupational therapy services, evaluating safety, assessing functional needs, and implementing personalized treatment plans to enhance patient independence and qu...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $131K *

Unlock your potential by leading a dynamic Salesforce CRM team focused on enhancing business processes and providing exceptional service support within a collaborative environment...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Engage in cutting-edge AI development by designing and scaling intelligent applications. Leverage Generative AI and modern tools to enhance productivity and integrate workflows within healthcare platf...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$197K - $328K *

Shape the future of sales strategies by leading a high-performing team focused on enterprise growth. Drive revenue initiatives through innovative partnerships and collaboration, establishing strong re...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Lead strategic initiatives in oncology nursing, optimizing field operations and education. Collaborate across functions to enhance performance and ensure compliance, driving impactful execution of por...

Boston, MARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Unlock potential by leading strategic initiatives across oncology franchises. Collaborate with cross-functional teams to enhance field operations, optimize resources, and drive effective nursing educa...

Denver, CORemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock strategic potential by leading oncology nursing initiatives across multiple franchises. Collaborate with cross-functional teams to enhance field execution, optimize operations, and drive impact...

Atlanta, GARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in developing and executing oncology nursing strategies across multiple franchises, ensuring alignment and resource optimization for high-impact field performance in a dynamic, cross-f...

Dallas, TXRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Accelerate progress at the forefront of Revenue Recovery by leading teams to optimize clinical coding and compliance. Drive operational excellence, enhance client satisfaction, and achieve financial t...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $185K *

Shape strategic success for key accounts by leading market access initiatives, collaborating with cross-functional teams, and driving growth through innovative solutions and insights in the managed ma...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$112K - $223K *

Lead global pharmacovigilance initiatives, ensuring compliance and operational excellence while guiding teams through complex safety reporting challenges across diverse therapeutic areas and trial pha...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $200K *

Lead the strategic execution of precision medicine initiatives for Veterans Affairs, driving integration and adoption of diagnostic technology while building executive relationships across healthcare...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $147K *

Drive clinical project performance by leading teams in the execution of research trials. Collaborate with stakeholders to ensure operational excellence, manage budgets, and mitigate risks while foster...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$70K - $94K *

Champion your career by leading audits and coding for medical records, ensuring compliance with industry standards and tackling fraud investigations to enhance service delivery across health plans...

Newark, NJRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Champion strategic partnerships with key opinion leaders in nephrology, driving impactful engagement and collaboration across teams to support the growth of FILSPARI® and enhance brand influence in th...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Join our dedicated team to provide comprehensive psychiatric care in an in-patient setting. Collaborate with healthcare professionals to develop individualized treatment plans for clients with diverse...

Southaven, MSRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.