Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$155K - $175K *

Unlock potential by leading the architecture and deployment of AI and workflow platforms, driving innovation across client engagements while collaborating with cross-functional teams to enhance operat...

Chicago, ILRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Tackle system build, support, and maintenance for Epic Inpatient Orders. Engage in enhancing workflows and managing inpatient provider billing while participating in upgrade cycles and on-call support...

Nashville, TNRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

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Brentwood, TNRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

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Bethesda, MDRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$85K - $95K *

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4 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Elevate healthcare technology as a senior analyst, optimizing complex Epic applications. Collaborate with stakeholders to enhance operational efficiencies and support application users, while mentorin...

Miami, FLRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$92K - $138K *

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  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

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1 week ago

  •   8 - 10 years exp.  •   Business Services

$255K - $348K *

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California, USRemote

Reposted 1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Pioneer the improvement of clinical documentation quality through collaboration with healthcare teams. Educate staff on documentation processes, enhance patient records, and ensure accurate clinical d...

Salt Lake City, UTRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion statistical programming excellence in oncology clinical trials. Lead programming activities, collaborate with cross-functional teams, and ensure high-quality deliverables from study start-up...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

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1 week ago

  •   11 - 15 years exp.  •   Information Technology

$143K - $193K *

Empower global clinical operations by leading process management initiatives, ensuring compliance and efficiency. Collaborate with cross-functional teams to enhance quality and drive innovations in cl...

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Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$114K - $210K *

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Delaware, USRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $135K *

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6 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

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3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

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Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

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United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$128K - $254K *

Lead the charge in managing clinical trials from initiation to closeout, ensuring project deliverables meet quality, time, and cost expectations while collaborating with multidisciplinary teams to dri...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $180K *

Unlock potential by managing key relationships with insurance partners, overseeing operations, and ensuring compliance in a dynamic, team-focused environment. Thrive in a collaborative setting that dr...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $117K *

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United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

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Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

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United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

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3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

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Arkansas, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.