Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$150K - $180K *

Join a team that's dedicated to enhancing patient access through strategic design and management of support programs. Oversee vendor relationships and ensure compliance while driving initiatives that...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$154K - $208K *

Lead statistical operations for Centralized Statistical Monitoring, ensuring study quality and compliance through innovative methodologies and analytical processes across clinical trial portfolios...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $200K *

Lead innovative clinical pharmacology efforts to advance ophthalmic drug development, ensuring technical excellence and strategic alignment across multiple programs. Collaborate with diverse teams to...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $140K *

Empower provider accounts post-launch by driving growth through strategic engagement, tailored training, and effective collaboration with internal teams. Cultivate relationships across diverse healthc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Shape the future of patient services by ensuring timely delivery of features and integrations. Collaborate across teams to enhance operational efficiency in a compliance-heavy environment, driving inn...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $150K *

Transform the future of business development by building strategic partnerships across key professional services. Drive growth through relationship-building and co-closing deals, while shaping a natio...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$172K - $287K *

Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...

RemoteRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Take ownership of delivering high-quality nursing care to hospitalized patients, assessing needs, administering treatments, and collaborating with healthcare teams to ensure optimal recovery and succe...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $90K *

Elevate patient care by delivering skilled nursing services in an inpatient setting. Collaborate with healthcare teams to assess needs, administer treatments, and prepare patients for successful disch...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $165K *

Lead transformative consulting engagements to enhance healthcare coding and middle revenue cycle processes, driving operational efficiency, compliance, and financial performance across diverse project...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Analyze healthcare data to enhance clinical insights and improve medication use. Collaborate with cross-functional teams to develop analytics tools and real-world evidence studies, driving better heal...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Lead compliance excellence by enhancing our Compliance Management System. Collaborate with cross-functional teams to mitigate risks and ensure adherence to mortgage banking regulations while fostering...

Tallahassee, FLRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$112K - $222K *

Manage complex clinical trials from initiation to completion, ensuring project success through effective coordination, communication, and teamwork across diverse functional areas and stakeholders. Dri...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Join a team that's dedicated to establishing a robust Quality Management System, ensuring compliance and excellence in global clinical development and commercialization. Lead quality initiatives and f...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform client relationships in the SUD/behavioral health sector, ensuring effective onboarding and ongoing engagement. Leverage your RCM expertise to enhance service delivery, client satisfaction...

Dallas, TXRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Optimize clinical research processes by conducting comprehensive monitoring visits, ensuring adherence to quality standards, and facilitating effective communication among project teams and sites acro...

Toronto, ONRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Transform your career by leading cross-functional teams to drive drug development strategies. Collaborate with key stakeholders to ensure successful execution of integrated plans, manage risks, and de...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$216K - $325K *

Lead enterprise security initiatives, driving strategy and governance while ensuring compliance and risk management. Collaborate across teams to protect information assets and foster a culture of secu...

CanadaRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Unlock the potential of clinical documentation by enhancing accuracy and quality. Collaborate with healthcare teams to educate on best practices, ensuring compliance and optimal reimbursement through...

Lebanon, NHRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the CDI Department by acting as a clinical and technical resource, facilitating communication between customers and leadership, and ensuring operational standards are met through effective workfl...

New Orleans, LARemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Serve as the primary contact for clients, driving engagement and service quality while fostering relationships with key stakeholders and leveraging expertise to enhance organizational growth and clien...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Shape the future of financial strategy by overseeing capital budgeting and investment analysis. Collaborate with leadership to ensure compliance and optimize financial performance across major project...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower healthcare technology by enhancing clinical systems and integrations. Collaborate with IT and business stakeholders to optimize workflows, manage projects, and ensure system performance across...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$186K - $279K *

Accelerate commercial growth by overseeing marketing operations and sales enablement strategies. Collaborate with cross-functional teams to optimize processes, enhance lead generation, and implement i...

Redwood City, CARemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$212K - $409K *

Drive innovation as a key member of our engineering team, leveraging your expertise in software engineering and data platforms to shape solutions that enhance customer experiences and meet business go...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.