Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$91K - $163K *

Join a team that's dedicated to improving healthcare outcomes through clinical review and collaboration. You'll engage in appeals and grievances processes, working closely with medical directors and p...

Minnetonka, MNRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $90K *

Transform your career with impactful auditing and training roles in risk adjustment. Collaborate with management to enhance coding compliance, drive performance improvement, and foster a culture of ex...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$246K - $332K *

Transform healthcare by leading national strategic account management efforts. Drive partnerships with key institutions, enhance patient care, and foster cross-functional collaboration to achieve comm...

RemoteRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Transform Drug Supply Chain Operations by leading cross-functional teams to establish reliable planning cadences and robust processes, ensuring continuous delivery of medication while driving efficien...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Empower your career by leading a clinical team while providing high-quality care to nursing center residents. Collaborate with medical professionals to enhance patient outcomes and mentor advanced pra...

New Jersey, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $195K *

Join a dynamic team to lead and manage clinical trials, ensuring timely execution and compliance. Collaborate with cross-functional partners and vendors to drive operational success in immunology rese...

Boston, MARemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead optimization governance efforts to enhance clinical system effectiveness, improve clinician satisfaction, and implement process improvements through collaboration, analytic oversight, and perform...

South Carolina, USRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $150K *

Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Champion clinical services initiatives, driving strategic content development and mentoring teams to enhance market access and client success. Lead projects, ensure compliance with standards, and reso...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $120K *

Transform patient care by delivering precise teleradiology interpretations across various shifts, utilizing AI tools to enhance workflow and maintain high-quality standards while collaborating with he...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$134K - $179K *

Lead the charge in bridging genomic variants with clinical insights, collaborating with scientists to automate and scale curation workflows. Drive innovation in AI/ML applications while ensuring softw...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$165K - $195K *

Engage in technical leadership and project management for healthcare commissioning. Drive business development, mentor staff, and ensure compliance with industry standards while collaborating with div...

Atlanta, GARemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $130K *

Optimize research operations by leading cross-team initiatives, establishing effective tracking systems, and maintaining a dynamic evidence repository. Drive efficiency and clarity in processes while...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$140K - $190K *

Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$153K - $210K *

Transform your career by partnering with teams to drive strategic growth through legal expertise in healthcare contracts, negotiations, and compliance. Collaborate with leadership to optimize performa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$155K - $171K *

Lead transformative consulting projects by conducting in-depth research and presenting strategic recommendations. Collaborate with clients and junior team members to drive high-quality deliverables an...

Chicago, ILRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive impactful HR strategies in a dynamic global environment, collaborating with senior leaders to align people initiatives with business goals. Contribute to a newly forming team focused on growth a...

Cambridge, MARemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Transform operational strategies and enhance cross-functional execution to support enterprise initiatives and improve healthcare practices. Collaborate with diverse teams to drive efficiency, effectiv...

Miami, FLRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$151K - $205K *

Elevate client success by driving technical innovation and transformation. Collaborate with cross-functional teams to develop strategic solutions, enhance client relationships, and execute multi-year...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$210K - $250K *

Drive impactful clinical trials by providing medical oversight and ensuring compliance with regulations. Collaborate with teams to manage safety profiles and support business development, enhancing dr...

Philadelphia, PARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$265K - $350K *

Deliver comprehensive virtual primary care, managing patient panels and enhancing remote health services. Collaborate with a dedicated support team to provide high-quality, patient-centered care in a...

Beverly Hills, CARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in developing and executing Total Rewards strategies that align with organizational goals. Drive operational excellence through project management, data analysis, and cross-functional...

Chicago, ILRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$148K - $175K *

Lead strategic initiatives and operational excellence across client portfolios, ensuring governance, performance management, and continuous improvement. Drive client satisfaction and financial account...

Chicago, ILRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$81K - $138K *

Drive the vision and strategy for Pharmacy Benefits Management, overseeing client services and ensuring satisfaction, performance, and profitability while leading a team to achieve business objectives...

San Diego, CARemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $110K *

Transform client relationships by driving engagement and optimizing healthcare outcomes through strategic planning, data analysis, and proactive issue resolution. Collaborate with internal teams to en...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.