Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$213K - $240K *

Lead statistical strategy for clinical development programs, guiding study design and analysis. Collaborate with cross-functional teams to ensure quality deliverables and compliance with regulatory st...

Menlo Park, CARemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's shaping the future of clinical utilization management. As a clinical expert, you'll engage with healthcare professionals to optimize specialty medication management and enhance pati...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$173K - $205K *

Shape the future of neurology by leading in vivo pharmacology studies, collaborating with cross-functional teams, and driving data-driven decisions for IND submissions in a dynamic biotech environment...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$327K - $450K *

Lead strategic clinical initiatives and operations for Indiana Medicaid, driving quality care and cost management while collaborating with stakeholders to enhance healthcare outcomes and business grow...

Indiana, USRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$223K - $233K *

Deliver strategic leadership in biologics process development, overseeing outsourced manufacturing and ensuring alignment with corporate goals while driving technical excellence in late-stage developm...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive strategic initiatives as Chief of Staff, enabling the AI & DT&A Practice Leader to excel while ensuring operational consistency and organizational clarity in a fast-paced, innovation-focused env...

Mclean, VARemote

Reposted 1 month ago

  •   8 - 10 years exp.  •   Business Services

$140K - $170K *

Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $222K *

Drive clinical adoption and enhance partnerships by leading a high-performing Medical Science Liaison team. Collaborate with sales and medical teams to educate stakeholders, influence decision-making...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive your career with a pivotal role in shaping product strategy and delivery, enhancing member experiences in healthcare. Collaborate across teams to define problems, prioritize outcomes, and levera...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Lead the charge in driving enterprise growth within healthcare by building relationships with national and regional health plans. Own new logo acquisition and expansion, leveraging a robust support sy...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$60K - $108K *

Engage in clinical assessments of healthcare services, ensuring quality care for members. Collaborate with medical professionals and manage grievances while maintaining productivity metrics in a remot...

Mesa, AZRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $118K *

Innovate the pharmacy landscape by architecting comprehensive TPA solutions, transforming complex requirements into streamlined operations, and enhancing client outcomes through strategic PBM partners...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$63K - $97K *

Support clinical trial operations by monitoring lab services, engaging with sites, and ensuring compliance with regulations. Collaborate with teams to enhance processes and deliver timely results for...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $170K *

Lead the charge in transformative project management, driving cross-functional teams to execute multichannel initiatives successfully. Cultivate client relationships, ensure project delivery on-time...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Lead and develop engineering teams focused on clinical data integration and insights. Drive the direction of data pipelines and ensure impactful, equitable health outcomes through effective collaborat...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$113K - $226K *

Lead the charge in optimizing healthcare processes by bridging strategy and execution. Collaborate with teams to enhance coding workflows, drive change management, and ensure alignment with strategic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$144K - $240K *

Transform healthcare delivery by leading strategic initiatives and optimizing infusion services. Drive client success through expert guidance, operational excellence, and innovative solutions, ensurin...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$177K - $278K *

Champion innovative patient recruitment strategies to enhance clinical trial engagement and retention. Lead a dynamic team, leveraging data and technology to optimize enrollment across diverse therape...

Massachusetts, USRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Empower your career by driving project delivery and managing Agile teams. Utilize AI tools to enhance decision-making, anticipate risks, and ensure timely outcomes. Collaborate with stakeholders to ma...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $138K *

Join a dynamic team to drive clinical trial success in Oncology, fostering strong investigator relationships and strategic enrollment strategies. Leverage your expertise to enhance trial execution and...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's architecting innovative virtual health solutions, enhancing communication capabilities for healthcare delivery. Collaborate on design, documentation, and implementation of mobile co...

Houston, TXRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Lead evidence generation and scientific communications to support innovative gene therapy initiatives. Collaborate with cross-functional teams to identify evidence gaps and execute strategic plans, en...

New York, NYRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $214K *

Join a team that's redefining healthcare product management through innovative supply chain solutions. Lead cross-functional initiatives and shape the future of resilience in healthcare with strategic...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Shape the future of brand strategy by leading integrated initiatives, translating insights into actionable plans, and collaborating with cross-functional teams to deliver impactful solutions across as...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Drive solutions for employer benefit ecosystems by leading pre-sales efforts, analyzing client needs, and designing tailored implementations for optimal savings and member engagement, collaborating cl...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.