Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$230K - $384K *

Shape the future of oncology by leading medical strategy and engagement across diverse customer segments. Collaborate with internal teams to deliver impactful medical insights and support clinical ini...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $145K *

Champion client success by managing strategic partnerships with mid-sized enterprises. Drive measurable outcomes through relationship management, consultative problem-solving, and cross-functional col...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $225K *

Transform relationships with key opinion leaders in rare neurological diseases, providing strategic insights and guidance to inform brand strategies and enhance engagement across medical and commercia...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $190K *

Unlock your potential by engaging key Gastroenterology stakeholders, driving product utilization, and exceeding sales goals through strategic collaboration and compliance in a dynamic healthcare envir...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform healthcare research by leading strategic projects and enhancing content quality. Collaborate with cross-functional teams to optimize operations and drive innovation in AI-enabled tools, ensu...

New York, NYRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Take ownership of IMP labeling processes, ensuring compliance with global regulations and quality standards while collaborating cross-functionally to support clinical trial timelines and enhance label...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$248K - $373K *

Transform healthcare delivery by leading clinical reviews and benefit determinations. Collaborate with a multidisciplinary team to enhance member outcomes and ensure cost-effective care while working...

Minneapolis, MNRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Transform workplace health by leading multiple occupational health clinics. Drive operational excellence, foster client relationships, and enhance team performance while ensuring exceptional patient c...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of compliance by leading a robust program that ensures regulatory adherence, fosters a culture of integrity, and collaborates across functions to mitigate risks and enhance operationa...

North Carolina, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$191K - $305K *

Champion innovative healthcare solutions by leveraging clinical expertise to enhance value-based strategies, drive operational excellence, and foster strategic partnerships for improved member care an...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$112K - $125K *

Champion customer success by managing strategic partnerships, optimizing client engagement, and driving value through innovative solutions in the healthcare sector. Collaborate with C-level executives...

CanadaRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$118K - $132K *

Drive customer success by managing partnerships and optimizing solutions for enterprise clients. Leverage your consulting expertise to engage C-level executives and enhance value in the healthcare sec...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$192K - $235K *

Lead analytical development and quality control for sterile parenteral products, ensuring regulatory compliance and successful product launches. Collaborate cross-functionally to establish strategies...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$116K *

Drive impactful site activation strategies, collaborating with cross-functional teams to ensure timely delivery of clinical projects while enhancing communication and mitigating risks throughout the p...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in enhancing partnerships within our Collaborative Care Program, focusing on driving referral growth and provider satisfaction through strategic engagement and support at various accou...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$252K - $305K *

Elevate operational excellence by leading the Circle National Trust's strategic initiatives, ensuring compliance, and driving performance across all business functions while collaborating with executi...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$120K - $150K *

Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$91K - $175K *

Join a team that solves complex data challenges, developing insights from multiple sources to support business decisions. You'll mentor peers and lead the implementation of advanced reporting solution...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$60K - $107K *

Transform clinical documentation processes by leveraging your expertise to enhance accuracy and compliance. Collaborate with healthcare providers to ensure optimal documentation practices and improve...

Concord, CARemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $210K *

Drive quality excellence in clinical programs by overseeing compliance, risk management, and vendor oversight. Collaborate cross-functionally to ensure adherence to GCP regulations and lead inspection...

San Francisco, CARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock compensation strategies by partnering with teams to analyze, model, and deliver data-driven solutions. Drive benchmarking, job architecture, and annual comp cycles to ensure equitable pay pract...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$177K - $338K *

Innovate the global medical strategy for a leading drug program. Drive launch readiness, evidence generation, and cross-functional partnerships while serving as the primary medical voice in product li...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Accelerate progress at the forefront of AI initiatives, driving strategic development and implementation across the Health Systems and Government Services unit to enhance operational excellence and cu...

Pennsylvania, USRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$213K - $240K *

Lead statistical strategy for clinical development programs, guiding study design and analysis. Collaborate with cross-functional teams to ensure quality deliverables and compliance with regulatory st...

Menlo Park, CARemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's shaping the future of clinical utilization management. As a clinical expert, you'll engage with healthcare professionals to optimize specialty medication management and enhance pati...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.