Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$80K - $95K *

Join a team that's redefining inpatient coding operations, ensuring quality and compliance while optimizing workflows. Lead a dedicated team to enhance documentation practices and support financial he...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Drive exceptional service delivery by leading a team of program managers, enhancing patient access to medications, and ensuring operational excellence while fostering a supportive work environment...

North Carolina, USRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$176K - $294K *

Engage with healthcare professionals to deliver medical expertise and insights in oncology. Drive strategic initiatives, foster collaboration, and enhance patient-centric communications across diverse...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$97K - $193K *

Lead the charge in ensuring clinical studies meet the highest standards of quality and compliance. Collaborate with sites and teams to drive successful execution and data integrity throughout the clin...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$246K - $332K *

Transform the future of field operations by leading strategic initiatives that enhance commercial effectiveness and drive measurable impact across customer-facing teams. Collaborate with cross-functio...

RemoteRemote

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$173K - $320K *

Shape the future of rheumatology by providing strategic medical oversight across clinical trials. Lead the innovation and development of groundbreaking therapies while collaborating with multidiscipli...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$107K - $199K *

Redefine pharmacy care by developing formularies and policies, enhancing quality programs, and driving initiatives that improve Medicaid services while collaborating with diverse teams and stakeholder...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$142K - $177K *

Champion innovative risk adjustment solutions by leveraging deep expertise to enhance payer and provider strategies. Collaborate with cross-functional teams to deliver impactful presentations and driv...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$119K - $186K *

Lead the charge in shaping a skills-powered talent ecosystem, driving strategy and governance for enterprise skills and talent marketplace initiatives that enhance workforce planning and career growth...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$134K - $184K *

Shape the future of customer success by leading a high-performing team, optimizing operations, and driving engagement and retention strategies to achieve key performance indicators and enhance client...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $240K *

Lead scientific strategy for clinical development of BHB-1893, collaborating with cross-functional teams to ensure data integrity and regulatory compliance. Drive protocol design, data analysis, and e...

San Francisco, CARemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$312K - $444K *

Unlock potential by leading and executing clinical trials for oncology products. Collaborate with teams to design studies, monitor safety, and ensure compliance with regulations while driving innovati...

Alameda, CARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$74K - $98K *

Elevate quality operations by leading corrective action plans (CAPs) for regulatory compliance. Collaborate with cross-functional teams to drive accountability, resolve barriers, and ensure sustained...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$246K - $332K *

Drive pediatric development strategy by integrating clinical insights and regulatory commitments across multiple therapeutic areas, ensuring effective execution from candidate transition to post-marke...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$131K - $303K *

Join a team that's at the forefront of healthcare analytics, driving innovation and strategy. You will support financial stewardship, operational excellence, and executive communications in a high-vis...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$76K - $110K *

Lead operational excellence in Medical and Clinical Affairs, managing grants, coordinating cross-functional teams, and ensuring efficient program execution to enhance healthcare outcomes and support s...

Woburn, MARemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $225K *

Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$113K - $181K *

Discover transformative opportunities by leading advanced analytics capabilities that drive performance and innovation in healthcare. Collaborate with cross-functional teams to create impactful data s...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $143K *

Join a dynamic team to lead Quality Assurance efforts in Long-Term Services and Supports. Oversee compliance, collaborate with external partners, and drive operational excellence while ensuring adhere...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$118K - $196K *

Lead the charge in developing and executing drug formulary strategies, ensuring compliance with regulations while collaborating with cross-functional teams to enhance pharmacy utilization management a...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $160K *

Shape the future of healthcare by building strategic partnerships that enhance behavioral health referrals. Collaborate with leadership to drive growth, develop tailored solutions, and maintain strong...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $130K *

Lead the charge in optimizing patient services through effective team management, strategic collaboration, and continuous improvement initiatives. Drive operational efficiencies while ensuring high-qu...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Deliver operational excellence by leading a dynamic team focused on enhancing member experience, driving efficiency, and achieving strategic goals while fostering employee engagement and development i...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Media

$120K - $145K *

Shape your career by providing strategic legal guidance across commercial, product, and regulatory domains. Collaborate with diverse teams to navigate complex agreements and compliance issues, ensurin...

Philadelphia, PARemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.