Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$180K - $220K *

Take ownership of clinical integrity and quality oversight in population health management. Drive evidence-based standards and ensure compliance with accreditation requirements while collaborating wit...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$160K - $200K *

Unlock potential by guiding mid-size companies through IT transformation, ensuring alignment with business goals while enhancing operational efficiency and compliance in the healthcare sector...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$130K *

Lead the charge in safeguarding and risk management for behavioral health services, ensuring compliance with regulatory frameworks while driving user satisfaction and engagement through strategic coll...

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5 days ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $142K *

Lead the charge in enhancing academic operations and faculty performance, ensuring compliance with accreditation standards while fostering student success through strategic curriculum development and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$215K - $408K *

Transform healthcare delivery by leading medical management and quality initiatives. Collaborate with clinical teams to enhance patient outcomes and drive cost-effective care while ensuring compliance...

Missouri, USRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$125K - $160K *

Drive client success in our lab network by managing relationships, ensuring renewals, and identifying growth opportunities. Collaborate across teams to enhance processes and improve client experiences...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$300K - $309K *

Transform patient care by leading medical strategy and clinical innovation. As a vital member of the team, you'll guide product development and trial execution while engaging with key stakeholders to...

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Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$193K - $322K *

Join a team that leads the charge in advancing clinical AI and technology, shaping solutions that enhance clinician experience and patient outcomes while navigating complex healthcare environments...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Healthcare

$230K - $240K *

Inspire excellence by leading provider support initiatives, enhancing satisfaction, accountability, and clinical quality. Drive process innovation and mentorship in a dynamic environment, ensuring com...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $170K *

Drive strategic excellence in sponsor operations, ensuring high-quality project delivery and alignment across enterprise programs. Manage a team of leaders to foster innovation and optimize operationa...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$69K - $101K *

Join us to enhance member health outcomes through holistic care management, collaborating with multidisciplinary teams to support individuals with complex needs. Utilize assessments and interventions...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$156K - $215K *

Drive data quality and integrity initiatives by leading cross-functional teams to enhance provider data management practices, ensuring compliance and operational excellence across the organization...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Transform risk management by leading a national team focused on claims, clinical risk reduction, and innovative AI solutions to improve outcomes. Drive strategic oversight and implement best practices...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$200K - $250K *

Make your mark at the forefront of clinical operations, driving global studies from strategy to execution while ensuring operational integration across teams and vendors for successful Phase 3 program...

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3 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in managing informatics projects from planning to delivery, ensuring timely decision-making and risk management. Collaborate with cross-functional teams to enhance health information e...

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3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$175K - $210K *

Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...

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4 days ago

  •   8 - 10 years exp.  •   Healthcare

$292K - $438K *

Shape the future of healthcare by leading clinical vision and quality initiatives. Collaborate with executive leaders to drive innovation and improve health outcomes across diverse federal programs, e...

Minneapolis, MNRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$130K - $150K *

Shape the future of healthcare technology by leading clinical strategy initiatives to enhance drug diversion prevention and ensure patient privacy compliance. Drive impactful relationships, educate st...

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Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Empower cross-functional teams to drive the Future of Medicine initiatives, ensuring scalable processes and compliance while enhancing patient safety and experience through strategic planning and exec...

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1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $225K *

Drive operational excellence by leading care team operations and enhancing member experiences. Build scalable systems and processes to ensure consistent, high-quality interactions across all touchpoin...

New York, NYRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$256K - $288K *

Lead the charge in clinical trial oversight and data interpretation, ensuring safety and efficacy of pipeline products through expert collaboration and strategic planning, aligning clinical activities...

Waltham, MARemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate your career by leading clinical education initiatives that enhance training programs and ensure high-quality patient care through collaboration and evidence-based practices...

Loveland, OHRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $167K *

Join a team that's dedicated to enhancing patient care through clinical leadership and operational excellence. Drive quality improvement initiatives and support compliance across multiple bases while...

New York, USRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $250K *

Transform clinical trials by ensuring patient safety and scientific integrity. Collaborate with stakeholders to uphold regulatory standards and optimize study protocols, while providing expert medical...

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1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $110K *

Accelerate progress at pediatric mental health care by leading clinical quality assurance and supervision, mentoring clinicians, and providing evidence-based therapy to children and families in a full...

Pennsylvania, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.