Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$122K - $158K *

Join a team that's dedicated to operational excellence in pharmacy care. Lead clinical operations, enhance patient experiences, and foster a culture of continuous improvement while ensuring compliance...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Transform medical strategies by leading a team of experts, ensuring compliance and scientific accuracy in communications, and fostering client relationships to drive innovative healthcare solutions...

New York, NYRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $231K *

Join a dynamic team as a strategic advisor, driving clinical priorities and operational excellence. Collaborate with leaders to translate strategy into action, enhance provider performance, and suppor...

Chicago, ILRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$134K - $249K *

Transform provider engagement strategies to enhance performance and quality across multiple business lines. Lead initiatives that optimize relationships, reduce costs, and align with organizational go...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $150K *

Join a team that's dedicated to advancing clinical research by managing complex studies, ensuring compliance with regulations, and leading cross-functional teams to achieve project milestones efficien...

Boston, MARemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by cultivating strategic relationships with benefits consultants and brokers. Drive revenue growth through effective partnerships, collaboration with cross-functional teams, and exper...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion seamless data integration across IT systems by leading complex projects, troubleshooting issues, and optimizing performance. Leverage your expertise in integration technologies to ensure data...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Lead complex integration projects, ensuring seamless data exchange across IT systems. Utilize your expertise in integration technologies to troubleshoot issues and optimize performance, while mentorin...

Englewood, CORemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$245K - $286K *

Elevate clinical quality assurance through strategic leadership and oversight of global trials, ensuring compliance with GCP regulations. Drive quality culture and inspection readiness while mentoring...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$225K - $265K *

Transform healthcare interoperability by leading product strategy and market growth. Leverage deep industry insights to enhance payer-provider collaboration, drive operational excellence, and oversee...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$94K - $130K *

Drive operational excellence by coordinating cross-functional processes, ensuring governance, and optimizing workflows to enhance efficiency and stakeholder experience across the enterprise...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$207K - $392K *

Empower provider network strategy by overseeing contracting, analyzing costs, and supporting market expansion. Lead initiatives to enhance network operations and ensure alignment with company objectiv...

Missouri, USRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$232K - $290K *

Lead the charge in optimizing workforce operations and analytics for multi-condition health care services. Develop strategies for capacity planning, staffing, and analytics to drive efficiency and sup...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $90K *

Champion project success by managing timelines, resources, and stakeholder communication. Drive seamless implementation experiences while collaborating with cross-functional teams to deliver value-dri...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $231K *

Optimize governance in Utilization Management by leading policy development, ensuring compliance, and enhancing operational efficiency across diverse healthcare lines. Collaborate with stakeholders to...

Connecticut, USRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Elevate clinical operations by leading teams in scheduling, coordination, and workforce planning. Drive performance through data insights while ensuring efficient processes and resource management as...

Addison, TXRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$109K - $149K *

Unlock vendor performance by leading analytics and risk adjustment initiatives across healthcare programs. Drive strategy, manage relationships, and ensure accurate reporting to optimize operational s...

Newark, NJRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Optimize client success by leading strategic relationships and enhancing revenue cycle performance. Drive measurable improvements, manage escalations, and ensure value realization across healthcare so...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$154K - $196K *

Unlock potential by leading strategic government programs, managing P&L, and driving operational excellence. Oversee contract delivery, mentor staff, and foster client relationships to ensure growth a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Ensure data integrity and compliance in clinical trials. Manage EDC development, oversee data cleaning, and liaise with vendors. Lead data management from initiation to close-out while optimizing data...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$216K - $324K *

Join a team that's shaping the future of oncology by leading cross-functional medical affairs initiatives, providing expert guidance, and collaborating with key stakeholders to enhance product strateg...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Empower strategic growth by managing health plan partnerships, driving revenue, and enhancing client relationships. Utilize your expertise in managed care to deliver impactful solutions and ensure cli...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $152K *

Champion program excellence by leading complex federal initiatives, managing multidisciplinary teams, and fostering strong stakeholder relationships to ensure successful delivery and client satisfacti...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $160K *

Lead the charge in managing multi-vendor coordination and cross-team delivery of patient-generated health data applications, ensuring alignment of technical execution with program goals to achieve imp...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Join a team that's redefining technology strategy for clients. As a strategic advisor, you'll align IT solutions with business goals, lead technology reviews, and optimize investments to drive measura...

California, USRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.