Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$145K - $165K *

Lead the charge in enhancing marketing technology platforms to optimize customer engagement and journey orchestration. Collaborate with cross-functional teams to deliver reliable solutions and improve...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$81K - $116K *

Lead strategic engagement initiatives by synthesizing data and insights into actionable recommendations. Manage complex workstreams independently, driving impactful strategies across diverse healthcar...

5 days ago

  •   5 - 7 years exp.  •   Media

$130K - $150K *

Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $95K *

Drive your career forward by enhancing real-time pipeline operations and supporting advanced leak detection systems in a collaborative environment. Contribute to critical projects and ensure operation...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$145K - $187K *

Pioneer innovative Digital Engineering solutions by leading the integration of Model-Based Systems Engineering and AI/ML methodologies, driving modernization efforts across complex Naval Nuclear Labor...

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$163K - $322K *

Join us to lead AI cybersecurity strategy initiatives, guiding clients through complex governance and risk challenges. Collaborate with cross-functional teams to deliver innovative solutions that enha...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$163K - $322K *

Unlock your potential as a Senior Manager in AI cybersecurity, guiding clients through complex governance and risk strategies while leading cross-functional teams to deliver innovative solutions and d...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Unlock potential by joining a dynamic Global SRE team focused on enhancing software reliability and observability. Collaborate with teams to implement best practices and innovative solutions, ensuring...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$164K - $282K *

Lead the charge in developing AI solutions for Neuroscience R&D, translating research needs into scalable tools. Collaborate with multidisciplinary teams to enhance scientific discovery and drive meas...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate your career by designing and optimizing data pipelines and infrastructure. Collaborate with cross-functional teams to enhance data delivery and support the agency's mission through innovative...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Champion the design and maintenance of scalable data pipelines and infrastructure, ensuring efficient data processing and delivery to support agency missions. Collaborate with cross-functional teams t...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Join a team that's dedicated to designing and optimizing data pipelines, ensuring efficient data processing and infrastructure management to support agency missions across cloud and on-premises enviro...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Optimize data infrastructure by designing and maintaining scalable pipelines to support agency missions. Collaborate with cross-functional teams to enhance data delivery and ensure high efficiency acr...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Champion the design and maintenance of scalable data pipelines and infrastructure, ensuring efficient data collection, processing, and delivery to support agency missions. Collaborate with cross-funct...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Unlock potential by designing and optimizing scalable data pipelines and infrastructure to support efficient data processing and delivery, enhancing the agency's mission through innovative data engine...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Transform data management by designing and optimizing scalable data pipelines and infrastructure, ensuring efficient processing and delivery of large datasets to support agency missions across cloud a...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Empower your career by designing and optimizing data pipelines and infrastructure. Collaborate with cross-functional teams to enhance data delivery and support the agency's mission through innovative...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Lead the design and optimization of scalable data pipelines and infrastructure, ensuring efficient data processing and delivery to support agency missions. Collaborate with cross-functional teams to i...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$137K - $235K *

Join a team that's transforming clinical and omics data into AI-ready assets. Lead the end-to-end data product lifecycle, ensuring quality and interoperability while mentoring junior engineers and col...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$123K - $197K *

Transform the landscape of AI by architecting and optimizing cutting-edge LLMs while collaborating with diverse tech teams to innovate and enhance applications for performance and accuracy in resource...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Shape the future of data governance by leading a team to manage third-party data compliance, ensuring operational excellence and regulatory adherence while fostering collaboration across business unit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$75K - $90K *

Drive cross-functional collaboration and optimize supply chain processes by leading SIOP initiatives. Utilize data analytics to enhance demand planning, inventory management, and financial alignment...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$75K - $90K *

Join a team that's transforming supply chain planning through data-driven insights and cross-functional collaboration. Your expertise will enhance demand forecasting, inventory management, and strateg...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $125K *

Champion the design and execution of control and automation strategies for industrial water treatment systems, collaborating with engineering teams to ensure safety, efficiency, and compliance through...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$66K - $105K *

Help us optimize financial performance through advanced analysis and modeling. Collaborate with business leaders on budgeting, forecasting, and strategic initiatives, providing insights to drive reven...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.