Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$70K - $196K *

Join a team that's pioneering scalable robotics solutions, driving innovation in AI and automation. Collaborate with experts to tackle industry challenges and enhance efficiency, safety, and cost-effe...

6 days ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Transform patient access by optimizing Epic Cadence workflows. Collaborate with clinical teams to enhance scheduling efficiency and support system improvements, ensuring seamless operations and superi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $220K *

Drive innovation by safeguarding AI systems while implementing robust security measures. Collaborate with diverse teams to ensure efficient AI integration and risk management, balancing security requi...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $160K *

Drive client success in our lab network by managing relationships, ensuring renewals, and identifying growth opportunities. Collaborate across teams to enhance processes and improve client experiences...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $120K *

Contribute to the development of innovative healthcare software by analyzing product requirements, documenting features, and ensuring compliance in Anatomic Pathology. Collaborate with cross-functiona...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $267K *

Unlock potential by developing robust software solutions that enhance compliance and security programs. Collaborate across teams to automate processes, streamline workflows, and ensure timely risk man...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Media

$115K - $125K *

Champion the configuration of our Ascend 2.0 platform by leading spec negotiations and ensuring data quality for client onboarding. Collaborate cross-functionally, manage multiple implementations, and...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$128K - $214K *

Champion user research strategies that shape digital experiences by turning data into actionable insights, collaborating across teams to enhance user engagement and optimize web performance globally...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$193K - $308K *

Join a team that's redefining statistical leadership in clinical research. Drive innovative study designs, enhance drug development effectiveness, and influence critical decisions through data-driven...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Join a team that's dedicated to ensuring sales compensation accuracy and integrity. You'll support deal desk operations and provide analytical insights, making a significant impact on revenue processe...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Empower your career by joining a dynamic SRE team focused on scaling Cloud services. Drive reliability, performance, and efficiency while leveraging your engineering skills to enhance infrastructure a...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$115K - $125K *

Empower your career by driving the integration and migration of data for a vital financial management system. Collaborate with experts to enhance system reliability and operational efficiency in a ful...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform healthcare insights by leading end-to-end quantitative market research. Collaborate with pharmaceutical teams to design impactful studies, analyze data, and deliver actionable recommendation...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $282K *

Lead the design and deployment of AI-driven evidence extraction workflows, enhancing clinical development in Neuroscience. Collaborate across teams to create scalable tools that improve data analysis...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Pioneer in search strategy, driving optimization across paid, organic, and AI channels. This role collaborates with cross-functional teams to enhance visibility, engagement, and customer acquisition t...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by serving as a top-tier technical expert, mentoring peers, and resolving complex challenges in customer success. Drive scalable processes and enhance team capabilities while engaging...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $300K *

Join us to bridge software and robotics for real-world solutions. Collaborate with cross-functional teams to develop, deploy, and enhance robotic applications, ensuring seamless integration and perfor...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $146K *

Transform semiconductor manufacturing by leading electrical design and compliance initiatives. Collaborate with cross-functional teams to enhance product safety and performance across advanced etch an...

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$189K - $303K *

Optimize executive hiring by leading end-to-end searches for Director+ roles, advising on org design and compensation, and mentoring the recruiting team to elevate hiring practices across the organiza...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $165K *

Engage clients by driving revenue through consultative sales, building strong relationships with law firms and corporations. Leverage industry insights to anticipate needs and deliver tailored solutio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$75K - $125K *

Lead the charge in enhancing regulatory reporting accuracy and compliance. Collaborate with cross-functional teams to analyze requirements, support strategic initiatives, and ensure submissions meet r...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Grow your career with an innovative startup, driving strategic enterprise deals and cultivating key relationships with Fortune 1000 executives to showcase cutting-edge AI technology and deliver except...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Transform the future of semiconductor assembly by designing and testing high-performance electro-mechanical systems. Collaborate with cross-functional teams to ensure reliability and manufacturability...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $167K *

Unlock potential by driving revenue insights and financial modeling, enhancing decision-making across finance and operations. Collaborate with stakeholders to refine processes and improve revenue reco...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $108K *

Drive innovation in automation systems, providing expert support and optimizing manufacturing operations. Collaborate across departments to improve process controls and compliance in the biopharma sec...

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.