Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$120K - $145K *

Drive the enterprise adoption of AI capabilities, managing product strategy and governance for agent solutions. Collaborate across teams to ensure innovation aligns with security, compliance, and oper...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$76K - $105K *

Support day-to-day operations for investment teams, collaborating across functions to enhance processes, manage budgets, and drive special projects from planning to implementation, ensuring alignment...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$126K - $201K *

Develop cutting-edge machine learning models to enhance perception performance for autonomous driving. Collaborate cross-functionally to tackle complex challenges and drive software solutions from pro...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$172K - $202K *

Champion innovative insights and strategies as a Senior Director, driving impactful research and analysis to empower clients globally. Engage with stakeholders to deliver actionable advice and elevate...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$223K - $290K *

Lead the technical strategy for data products, driving clinical data capabilities and insights. Collaborate with teams to optimize data ingestion processes and implement AI-assisted development workfl...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$98K - $109K *

Join a team that's dedicated to optimizing IT operations and ensuring compliance. You'll manage daily IT tasks, support security initiatives, and collaborate on maintaining audit readiness, all while...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$140K - $170K *

Lead the charge in optimizing our marketing technology ecosystem, ensuring seamless integration and support across platforms. Collaborate with cross-functional teams to translate business needs into e...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $185K *

Shape the future of data engineering by leading the architecture and evolution of a robust enterprise data platform, ensuring reliability and integration across analytics, reporting, and AI capabiliti...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$115K - $130K *

Join a team that's dedicated to developing innovative web and cloud applications. In this role, you'll lead projects, mentor junior engineers, and collaborate with cross-functional teams to deliver hi...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$169K - $267K *

Lead the charge in driving innovative sales strategies for cloud-based data solutions, engaging senior management, and mobilizing ecosystem partners to achieve a $32M+ annual sales target across diver...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$169K - $267K *

Champion net-new sales opportunities across diverse industries, driving a $32M+ annual target. Collaborate with ecosystem partners to deliver AI-driven solutions, engage senior management, and ensure...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$70K - $235K *

Transform your career by designing AI-powered commerce solutions. Lead the development of intelligent systems, ensuring scalable and secure deployments that align with business objectives while collab...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Business Services

$70K - $235K *

Lead the design and implementation of AI-powered commerce solutions, ensuring scalable and secure deployments. Collaborate with clients to align AI strategies with business goals while optimizing mult...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Develop and maintain embedded software for advanced robotics, ensuring system compatibility and performance. Collaborate with cross-functional teams, support users, and lead technical projects while g...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$180K - $190K *

Empower our team to drive innovation by developing crucial AI tools that enhance operational efficiency. Oversee governance, training, and metrics to ensure impactful adoption across departments while...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$105K - $202K *

Innovate and build AI-native products that automate complex workflows. Collaborate with cross-functional teams to design, develop, and deploy full-stack applications, ensuring reliability and performa...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $339K *

Transform programmatic advertising by defining and scaling innovative products, collaborating across teams to enhance advertiser experiences while ensuring alignment with strategic business goals...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$185K - $260K *

Champion security excellence by designing and implementing robust software solutions. Collaborate with teams to enhance security practices, conduct code reviews, and respond to incidents, ensuring a s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Drive the development of LLM-based agents, ensuring robust production systems, effective evaluation, and seamless integration with company data while maintaining security and operational excellence ac...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$109K - $125K *

Unlock potential by transforming complex data into actionable insights that drive enterprise strategy and decision-making. Collaborate across teams to develop reporting tools and metrics that enhance...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$98K - $163K *

Explore innovative data solutions to enhance decision-making and operational efficiency for healthcare clients. Collaborate on analytics, machine learning, and application development to drive impactf...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Elevate your career by leading the design and deployment of advanced machine vision systems. Drive innovation in automated inspection applications, integrating cutting-edge technologies to enhance man...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Innovate finance data analytics to enhance cross-functional performance. Lead strategic initiatives, manage project execution, and drive standardization for impactful financial reporting and decision...

Philadelphia, PARemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the Finance Data Analytics function to enhance cross-functional performance, drive strategic objectives, and deliver integrated outcomes through effective management of analytics initiatives and...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Shape the future of talent acquisition by driving full-cycle recruiting across commercial teams. Collaborate with leaders to build a high-performing workforce that aligns with our mission and values...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.