Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
$110K - $130K *
Innovate in cancer research by designing and deploying advanced AI and machine learning solutions. Collaborate with cross-functional teams to develop multimodal models integrating diverse clinical dat...
1 week ago
Associate Director, Client Media Solutions
$100K - $115K *
Champion integrated media strategies for pharmaceutical clients, driving engagement and measurable outcomes. Lead cross-functional teams to develop innovative solutions that address complex healthcare...
Yesterday
Principal Attack Engineer, AI/LLM
$238K - $280K *
Shape the future of AI/LLM security by leading innovative offensive strategies, defining technical vision, and driving cross-company initiatives to enhance NodeZero's capabilities in identifying and e...
5 days ago
Associate Director, Client Media Solutions
$95K - $120K *
Accelerate progress at the intersection of media and healthcare by leading integrated planning and strategy for pharmaceutical clients. Drive impactful engagement initiatives while mentoring a talente...
1 week ago
Senior ML Operations Engineer II - Monetization
$211K - $248K *
Lead the charge in managing the complete ML model lifecycle, ensuring robust deployment, monitoring, and continuous improvement. Collaborate with data scientists to enhance model performance and opera...
2 weeks ago
$75K - $90K *
Transform financial insights into strategic initiatives, supporting planning and analysis as the organization scales. Collaborate across teams to enhance budget management, reporting, and performance...
Reposted 1 week ago
$115K - $145K *
Elevate your career by designing and optimizing data pipelines that empower analytics and AI solutions. Collaborate with cross-functional teams to ensure data integrity and governance while mentoring...
2 days ago
Project Environmental Scientist, Geologist, Engineer or Hydrogeologist
$85K - $100K *
Empower project success by managing environmental investigations and remediations. Develop client relations, lead fieldwork, and guide staff while ensuring compliance and excellence across diverse pro...
Reposted 2 weeks ago
Senior Technical Program Manager
$125K - $150K *
Transform complex customer implementations into seamless successes by owning the delivery lifecycle, driving technical discussions, and ensuring stakeholder satisfaction from kickoff to go-live. Your...
6 days ago
Manager II, Engineering - Kubernetes Platform
$177K - $364K *
Empower a team of engineers to enhance Kubernetes platform infrastructure, driving reliability, security, and efficiency while collaborating across departments to achieve strategic goals and operation...
2 weeks ago
$80K - $95K *
Engage in quantitative research and analysis to enhance equity portfolio strategies. Collaborate with investment teams to develop tools and optimize stock selection models, leveraging data and AI appl...
4 weeks ago
Project Environmental Scientist, Geologist, Engineer or Hydrogeologist
$80K - $95K *
Grow your career with a dynamic team managing environmental projects, supervising investigations, and developing client relationships. Gain valuable project and staff management experience while contr...
Reposted 2 weeks ago
Senior Marketing Operations & Analytics Manager
$145K - $185K *
Join a dynamic team as a Senior Marketing Analytics Manager, driving marketing performance measurement and insights. Collaborate cross-functionally to build impactful reporting and attribution models...
2 weeks ago
Senior Director, Client Sales & Insights
$100K - $130K *
Drive commercial activation and revenue growth for a multi-million-dollar portfolio, leveraging strategic insights and AI to enhance client engagement and decision-making. Lead cross-functional teams...
6 days ago
$195K - $270K *
Lead a dynamic team of analysts and data scientists to optimize marketing strategies, driving impactful insights and experimentation across channels to enhance growth and performance metrics for the o...
1 week ago
$110K - $140K *
Shape the future of IT compliance by leading SOX, Cyber Essentials, and CMMC initiatives. Collaborate with cross-functional teams to ensure regulatory adherence and enhance cybersecurity frameworks wh...
2 days ago
$95K - $115K *
Shape the future of electrical engineering by collaborating with design teams, ensuring technical compliance, and enhancing performance across diverse projects. Join us to tackle innovative challenges...
3 days ago
Senior Full-Stack Engineer - Case Strategy
$120K - $145K *
Shape the future of healthcare by owning and optimizing AI systems. Design and deliver scalable ML solutions that transform operations, enhance decision-making, and create real-world impact across cri...
Reposted 3 weeks ago
Experienced QA Engineer with Hands-on Automation and AI Skills
$105K - $207K *
Unlock the potential of quality assurance by leading innovative testing solutions, interfacing with clients, and driving excellence in technology delivery across diverse environments and platforms...
2 days ago
Experienced QA Engineer with Hands-on Automation and AI Skills
$105K - $207K *
Join a team that's transforming technology through innovative QA solutions. Leverage your expertise to enhance client success by leading testing strategies and ensuring quality across diverse platform...
2 days ago
$75K - $90K *
Elevate financial insights as a Senior Financial Analyst, partnering with leaders to drive strategic planning, budgeting, and reporting. Leverage your analytical skills to enhance operational performa...
1 week ago
$63K - $169K *
Unlock potential by leading data-driven transformations that integrate telemetry insights across operational and employee experience domains, establishing KPIs and enabling informed decision-making th...
2 weeks ago
$59K - $156K *
Drive impactful digital transformations by delivering telemetry-driven insights. Collaborate across teams to establish KPIs, identify trends, and enable data-driven decision-making through advanced an...
2 weeks ago
Software Engineer 4/5 - Model Serving Systems, AI Platform
$466K - $500K+*
Unlock potential by developing scalable AI/ML model serving infrastructure. Collaborate cross-functionally to enhance performance and availability of high-traffic systems, driving innovation in a dyna...
1 week ago
$133K - $173K *
Shape the future of AI governance by designing frameworks and policies that ensure responsible innovation and effective risk management across the enterprise. Collaborate with cross-functional teams t...
1 week ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.