Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.
Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.
Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.
Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.
Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.
$80K - $95K *
Shape the future of data analytics by leveraging innovative technologies to develop scalable data products. Collaborate with cross-functional teams to ensure data quality and deliver actionable insigh...
Reposted today
$150K - $180K *
Unlock potential by leading technical vision and mentoring engineers. Drive modernization and collaboration across teams to build resilient, scalable infrastructure while fostering a high-performance...
1 week ago
$104K - $179K *
Champion the evolution of data platforms by designing and implementing scalable solutions. Collaborate with teams to enhance data management and support junior members, all while driving impactful pro...
Today
$147K - $217K *
Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...
4 weeks ago
Audit Policy Analyst, Post-Acute Services
$80K - $95K *
Innovate post-acute payment integrity by developing and optimizing audit concepts for DME, home health, and infusion therapy claims. Collaborate cross-functionally to ensure compliance and enhance ope...
2 weeks ago
Senior Architect - Data Processing Systems, Analytics and Data Intelligence
$184K - $356K *
Transform data processing architectures by optimizing performance and efficiency. Collaborate with diverse teams to enhance user experiences and drive innovation in hardware-software co-design for cut...
Reposted 2 weeks ago
Global Head of Customer Success Engineering
$242K - $285K *
Transform the customer success landscape by leading technical teams, driving integration health, and enhancing revenue through strategic partnerships and innovative solutions in the programmatic ecosy...
6 days ago
$160K - $280K *
Join us to architect and build a cutting-edge web platform, driving marketing innovation through AI agents. Own technical decisions, enhance user experiences, and ensure seamless integration with our...
3 weeks ago
$130K - $155K *
Develop and oversee the governed context layer for AI systems, ensuring robust data architecture and standards. Collaborate with digital workers to enhance data engineering practices and drive innovat...
1 week ago
$80K - $100K *
Unlock your potential by contributing to enterprise EDI and integration projects. Collaborate with experienced engineers to design, implement, and optimize solutions, enhancing customer satisfaction a...
1 week ago
$170K - $200K *
Transform customer experiences by providing technical expertise and solutions. Collaborate with sales and engineering teams to deliver impactful product demonstrations and address technical challenges...
1 week ago
$120K - $140K *
Innovate cloud solutions by designing and automating infrastructure in Cloud.gov and Azure. Collaborate with teams to enhance performance and security, driving impactful results for clients while shap...
Reposted yesterday
$125K - $150K *
Innovate AI-driven business applications by designing Python services and APIs that enhance data processing capabilities in both cloud and on-premises settings, ensuring robust performance and seamles...
Reposted 5 days ago
$86K - $107K *
Lead advanced analytics projects that drive strategic decisions, optimize sales productivity, and enhance operational efficiency. Collaborate with executives to deliver data-driven insights and implem...
5 days ago
Senior ITCR / Requirements Analyst
$79K - $122K *
Shape the future of IT capabilities by leading requirements analysis and advisory support for a Department of War agency. Collaborate with stakeholders to deliver data-driven insights and enhance ente...
1 week ago
Senior Staff Applied Scientist, Science Platform
$232K - $325K *
Join a dynamic team to lead the development of advanced analytics tools, leveraging your expertise in statistics and machine learning to drive impactful decision-making across the organization...
2 days ago
$125K - $150K *
Transform business workflows by developing and maintaining applications that enhance productivity and information sharing across teams. Collaborate with IT and business units to deliver innovative sol...
Reposted 3 days ago
Integrations Engineer, AI Services
$110K - $130K *
Unlock potential by designing and delivering scalable AI-powered integrations for nonprofits. Collaborate closely with clients to understand their needs, build solutions, and productize offerings that...
2 days ago
Web Strategy & Optimization Lead
$148K - $186K *
Unlock potential by leading web growth strategies that drive measurable business outcomes. Collaborate with cross-functional teams to optimize user experiences and execute high-impact initiatives from...
4 weeks ago
Senior Data Scientist - R&D DDSAI - Preclinical Sciences & Translational Safety
$120K - $150K *
Unlock potential by leveraging advanced machine learning and data engineering to drive impactful decisions in pharmaceutical R&D. Collaborate with multidisciplinary teams to create AI-ready datasets a...
5 days ago
Senior Business Insights Analyst
$110K - $131K *
Transform complex data into actionable insights, partnering with leaders to enhance strategic decision-making and drive organizational performance through advanced analytics and reporting frameworks...
1 week ago
$80K - $95K *
Join a dynamic engineering team to design and support multi-security-level systems, focusing on secure network architectures and virtualization technologies. Collaborate on system integration, testing...
1 week ago
Lead AI and Data Solution Engineer
$200K - $215K *
Drive innovation in data engineering and AI solutions, leading the design and deployment of scalable systems. Collaborate with cross-functional teams to enhance business value through advanced technol...
4 weeks ago
$120K - $145K *
Champion data excellence by designing and optimizing scalable data platforms. Collaborate with cross-functional teams to enhance performance and drive innovation in data processing, ensuring alignment...
Yesterday
Senior Digital Paid Ad Manager
$149K - $185K *
Lead the strategy and execution of paid digital advertising programs, optimizing campaigns across multiple channels to drive measurable pipeline and revenue impact. Collaborate with cross-functional t...
3 weeks ago
What kinds of high-paying jobs can I find in Pennsylvania?
Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.
Do Pennsylvania jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.
How can I narrow my search for jobs in Pennsylvania?
Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.
Are remote or hybrid jobs available in Pennsylvania?
Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.