Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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$109K - $125K *

Optimize enterprise strategy and analytics by transforming complex data into actionable insights. Collaborate across functions to enhance decision-making and support strategic initiatives through effe...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $200K *

Innovate robust ML infrastructure to enhance AI capabilities, ensuring seamless model deployment and performance. Collaborate with teams to streamline processes and drive impactful ML systems from res...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$82K - $137K *

Transform business insights into actionable data solutions by collaborating with stakeholders, analyzing data quality, and ensuring effective integration of analytical products to drive operational ef...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Transform enterprise architecture in healthcare by driving innovation and strategy. Collaborate with stakeholders to design scalable solutions, optimize processes, and lead AI initiatives, ensuring al...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $185K *

Lead and inspire engineering teams to deliver high-quality digital products, ensuring alignment with business priorities while fostering a culture of collaboration and continuous improvement in a dyna...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Unlock potential by managing complex commercial analyses, revenue reporting, and settlement calculations. Collaborate with clients and internal teams to optimize financial performance and ensure accur...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$149K - $224K *

Drive analytics excellence by leading a team to deliver impactful insights, enhance reporting capabilities, and support strategic decision-making across diverse business functions. Foster collaboratio...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$140K - $160K *

Architect the future of intelligent K-12 assessment systems by designing a robust knowledge architecture that integrates AI, learning science, and psychometrics. Innovate and build foundational struct...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Elevate data-driven decision-making by analyzing clinician networks to optimize patient care. Collaborate with cross-functional teams to enhance operational efficiency and improve healthcare outcomes...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$105K - $202K *

Create innovative AI-powered healthcare products by transforming complex workflows into intuitive applications. Collaborate with cross-functional teams to deliver impactful user experiences and own fe...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Unlock potential by leading innovative laboratory research and trials to enhance product properties. Collaborate across functions to apply expertise and support continuous improvement within operation...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$170K - $200K *

Join a dynamic team to design and implement scalable data pipelines, transforming diverse data sources into actionable insights. Collaborate with cross-functional experts to drive innovation and maint...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Transform manufacturing operations by leading automation equipment design, identifying cost-saving opportunities, and enhancing existing systems. Collaborate with suppliers and teams to ensure timely...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$149K - $198K *

Elevate your career by leading data-driven evaluation methodologies for autonomous systems. Collaborate with cross-functional teams to ensure performance metrics align with safety standards, driving i...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$149K - $198K *

Join a team that's redefining performance evaluation for autonomous systems. Lead initiatives to enhance testing methodologies, ensuring rigorous, data-driven insights that support safe and efficient...

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$100K - $130K *

Unlock your potential as a Senior Financial Analyst, driving financial insights and models to support growth. Collaborate across teams to enhance forecasting accuracy and optimize performance, playing...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Finance & Insurance

$145K - $175K *

Unlock your potential as a Principal Data Engineer, driving the evolution of our data platform. Lead architecture, design scalable pipelines, and champion AI-assisted development while collaborating a...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Hospitality & Recreation

$144K - $288K *

Lead the charge in developing cutting-edge digital applications leveraging AI, optimizing performance across major cloud platforms while driving excellence in software engineering practices and collab...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Elevate your career by designing and developing high-scale Identity Resolution systems. Collaborate with cross-functional teams to create reliable, secure, and high-performance solutions that link and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$125K - $225K *

Unlock innovation by building scalable, user-centric applications in TypeScript and React. Collaborate with engineering teams to enhance AI-driven solutions, ensuring top performance in ML observabili...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$265K - $295K *

Lead the charge in community engagement, fostering trusted relationships with local stakeholders to ensure Anthropic's infrastructure projects benefit Indiana and Kentucky communities throughout their...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $155K *

Transform AI initiatives by managing a diverse team of data scientists, driving model innovation and implementation for National Security clients, while fostering collaboration and excellence across e...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$194K - $361K *

Drive enterprise-scale Data and AI solutions, shaping strategies and leading cross-functional teams to deliver measurable outcomes while fostering innovation and digital transformation across the orga...

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Innovate financial strategies and insights to empower leadership decisions, enhance resource management, and drive organizational success through effective analysis and collaboration across diverse te...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $160K *

Transform data operations by leading our Snowflake platform migration, ensuring security, reliability, and cost efficiency while collaborating across teams to standardize practices and enhance data ma...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.