Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$80K - $145K *

Join a team that's advancing data analytics for VA modernization initiatives. Utilize SQL and Python to drive AI-enabled insights, enhance operational workflows, and support decision-making through ri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$152K - $283K *

Elevate enterprise data strategy by engineering reliable, compliant data products. Lead data governance and innovation to enhance data-driven decision-making, ensuring high-quality data delivery acros...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $190K *

Transform data into actionable insights by leading a team of data scientists and analysts. Drive advanced analytics initiatives, foster collaboration with stakeholders, and ensure high-quality deliver...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$201K - $251K *

Transform workforce intelligence by leading People Analytics, establishing data governance, and driving strategic decision-making in a high-growth environment. Collaborate across functions to enhance...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $283K *

Drive impactful data analyses and innovative experiment design to enhance product strategies and optimize Ads Marketplace performance, collaborating with cross-functional teams in a flexible, hybrid w...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$127K - $228K *

Lead the charge in managing complex AI/ML development projects globally, ensuring quality and best practices while providing expertise and driving innovation in technology solutions across the organiz...

2 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$150K - $180K *

Optimize your career by leading insights-driven strategies that shape brand decisions. Collaborate across functions to deliver actionable market research and analysis, driving impactful outcomes in a...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$232K - $325K *

Empower innovation by serving as a leading expert in relevance evaluation. Collaborate to enhance ranking and recommendation systems, driving product strategy through rigorous analysis and shaping the...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Media

$120K - $145K *

Drive impactful digital media strategies by leading insights and innovation. Collaborate with clients to optimize media investments, manage a talented team, and present actionable insights that enhanc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$500K+*

Lead the charge in developing a next-gen AI/ML serving and inference platform. Collaborate with cross-functional teams to architect scalable solutions that empower ML practitioners across diverse doma...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Hospitality & Recreation

$153K - $213K *

Drive efficiency by automating internal processes, enhancing productivity across teams. Collaborate with stakeholders to identify bottlenecks, implement AI solutions, and ensure measurable impact on w...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$165K - $243K *

Elevate healthcare data solutions by leading a team of engineers to deliver scalable data infrastructure, ensuring compliance and operational excellence while translating stakeholder needs into action...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Transform AI/ML solutions by developing scalable applications that enhance operational efficiency and mitigate risk. Collaborate with stakeholders to create responsible, production-ready models that a...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$180K - $195K *

Drive impactful data science initiatives by building and operating ML systems. Manage end-to-end processes from modeling to evaluation, while mentoring a lean team and collaborating across departments...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$180K - $225K *

Lead the charge in transforming AI strategies into impactful solutions for revenue teams, collaborating closely with GTM leaders to drive innovation and measurable outcomes while enhancing engineering...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Take ownership of revenue modeling and forecasting, leveraging AI to automate processes and enhance reporting accuracy. Collaborate across functions to drive financial insights and support strategic d...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$72K - $126K *

Join us to leverage your expertise as a Technical Analyst, driving IT service delivery and enhancing pharmaceutical technology support through data analysis and innovative solutions...

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $161K *

Reimagine enterprise AI solutions by deploying and supporting AI assistants, ensuring client readiness, and driving adoption. Collaborate with cross-functional teams to transform experimentation into...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in advancing AI applications in healthcare by developing intelligent agents that uncover financial opportunities within complex datasets, transforming manual analyses into scalable wor...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Advance your career by shaping the employee experience from onboarding to integration. Lead initiatives that enhance new staff satisfaction and productivity while collaborating across teams to improve...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$129K - $177K *

Lead the charge in designing and delivering AI capabilities for a platform, integrating advanced workflows and intelligent analysis while actively contributing to production code and managing a small...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $185K *

Optimize product performance through data-driven insights, collaborating with cross-functional teams to define metrics, analyze customer behavior, and support strategic planning for impactful product...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Join a team that's redefining data solutions by leading the Data Products & Engineering department, shaping cutting-edge data architectures and innovative client-facing analytics solutions that drive...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Elevate business growth by harnessing market insights and customer data. Collaborate across teams to identify strategic opportunities, conduct competitive analysis, and develop actionable plans for di...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$178K - $294K *

Join a team that's redefining data engineering and analytics. Lead strategy, architecture, and execution of scalable data solutions while mentoring professionals and driving business outcomes through...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.