Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$125K - $145K *

Lead campaign strategy and execution for oncology pharma marketing, driving performance optimization and cross-functional collaboration. Own end-to-end campaign management, ensuring alignment with bus...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Take ownership of client relationships and campaign performance, managing a portfolio of accounts. Lead strategy discussions, optimize Meta campaigns, and ensure client satisfaction through proactive...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K *

Partner with us to lead recruitment initiatives and workforce planning, driving talent acquisition strategies across skilled nursing and assisted living sectors. Collaborate with leaders to build stro...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $140K *

Join a team that's redefining privacy standards by leading initiatives that integrate privacy by design across business and technology. Collaborate with cross-functional teams to translate complex reg...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $110K *

Join a team that's dedicated to enhancing software quality through innovative testing strategies. Collaborate with cross-functional teams to ensure reliable applications that support clinical research...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $120K *

Lead the charge in quality engineering for critical assessment platforms, driving testing excellence and automation maturity. Collaborate with cross-functional teams to ensure reliability and scalabil...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$130K - $154K *

Lead full-lifecycle recruiting efforts, partnering with hiring managers to build strong candidate pipelines and improve processes across diverse talent markets. Drive data-driven insights to enhance h...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Empower your software engineering career by directing AI to deliver full-stack solutions. You'll manage end-to-end feature development, leveraging AWS and AI tools to enhance productivity and quality...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $140K *

Empower your career by driving product marketing success through strategic commercialization, effective messaging, and cross-functional collaboration. Lead initiatives that translate complex data solu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $135K *

Shape the future of digital services by developing user-centric applications and enhancing software engineering practices. Collaborate with cross-functional teams to deliver impactful solutions for fe...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$70K - $205K *

Drive your career with innovative AI solutions in the Insurance sector. Leverage advanced analytics and machine learning to enhance decision-making processes, collaborating with diverse teams to deliv...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$112K - $131K *

Elevate your career by leading complex financial analyses and strategic initiatives. As a senior contributor, you'll drive enhancements in reporting, support business decisions, and mentor team member...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$97K - $126K *

Transform marketing strategies by connecting buyer needs with sales execution. Lead integrated campaigns, enhance customer engagement, and drive growth through innovative go-to-market planning and col...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$183K - $229K *

Drive the evolution of AI architecture, enabling teams to build scalable AI solutions on a robust platform. Collaborate with product teams to translate roadmaps into actionable designs, ensuring high...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$150K - $180K *

Champion innovative AI platform architecture and drive enterprise-level integration of machine learning, ensuring security, accuracy, and reliability across systems while mentoring teams to elevate te...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$125K - $150K *

Champion the development of scalable, cloud-native applications, enhancing data pipelines and integrations. Collaborate with teams to transform raw data into actionable insights, driving improvements...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Optimize integration processes by bridging technical gaps between systems. Collaborate with campus IT to ensure seamless data flows, troubleshoot issues, and enhance integration reliability for succes...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Grow your career by owning enterprise sales processes, building relationships, and closing deals in home décor, beauty/wellness, and online retail. Drive significant revenue growth by leveraging consu...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $149K *

Analyze and enhance IT infrastructure through secure cloud solutions, ensuring 24x7 availability. Collaborate with teams to streamline workflows, improve system reliability, and tackle complex challen...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$92K - $166K *

Unlock potential by leading logistics analysis and execution for naval programs, ensuring effective support for maintenance, training, and compliance in a dynamic environment. Collaborate with diverse...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Technical Services

$200K - $240K *

Champion the future of energy by providing expert consulting on utility prudence, managing client engagements, and delivering impactful testimony on modernization and rate cases. Collaborate with team...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$180K - $220K *

Drive the development of innovative security systems using AI/ML, managing risk across identity and access management. Collaborate with cross-functional teams to enhance security while maintaining ope...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$82K - $172K *

Empower mission success by establishing automated testing frameworks and executing comprehensive test plans. Collaborate with teams to enhance IT service delivery and ensure high-quality performance a...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead architecture and engineering projects from planning to delivery. Collaborate with multidisciplinary teams, manage budgets and schedules, and ensure quality standards while fostering strong client...

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.