Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$80K - $95K *

Transform cybersecurity efforts by analyzing and mitigating risks in critical IT infrastructures. Collaborate with diverse teams to enhance mission assurance for Air Force weapon systems, ensuring rob...

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Join our team to drive revenue growth by winning new business and establishing strategic relationships with key accounts. Collaborate with senior management to develop effective strategies and ensure...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $120K *

Shape the future of technical proposals by collaborating with cross-functional teams to create compelling, scientifically accurate documents that meet client needs and drive business success in the li...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Innovate the go-to-market systems by building AI agents and infrastructure that drive pipeline efficiency, ensuring seamless integration and reliability across sales and marketing operations...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Elevate your career by leading strategic finance pilots to drive AI model training and evaluation. This hands-on role combines financial expertise and operational leadership to transform emerging proj...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$190K - $280K *

Transform talent acquisition by leading a global team to enhance recruiting efficiency, drive strategy, and leverage AI for measurable improvements across diverse markets while ensuring compliance and...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $166K *

Elevate your career by managing clinical trial data processes from start to finish. Collaborate with teams to ensure quality and compliance while overseeing database development and testing for impact...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$111K - $167K *

Optimize the customer journey by leveraging analytics and strategic insights to enhance pipeline generation, forecasting, and sales enablement for a growing Property Care business. Collaborate cross-f...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $140K *

Shape the future of cooling technology by developing cost models for large-scale systems. Collaborate with leadership and engineering to optimize pricing strategies, enhance margins, and drive growth...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Elevate your career by building and maintaining CI/CD pipelines, administering servers, and leading DevOps initiatives. Collaborate with teams to enhance application performance and security while men...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Help us advance our utilities and data center solutions by leading strategic customer partnerships, identifying market needs, and fostering scalable growth for a trusted workforce collaboration in cri...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $145K *

Lead the charge in transforming patient engagement by integrating booking into our core product. Drive innovative experiments and optimize multi-channel outreach to ensure underserved communities rece...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform the SAP sales landscape by leveraging your extensive network and expertise to drive new business acquisition in the manufacturing sector. Own the full sales cycle, from lead generation to cl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$250K - $300K *

Empower the future of AI in commerce media by leading strategy and execution across AI Labs and Data Science. Drive customer engagement, scale capabilities, and enhance product impact while building a...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$128K - $205K *

Drive the analytical strategy for fraud risk mitigation in digital transactions. Collaborate with cross-functional teams to develop metrics and frameworks that enhance decision-making and risk detecti...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $90K *

Elevate your career by ensuring top-notch quality in technical deliverables. Collaborate with stakeholders to enhance cybersecurity documentation and support critical DoD programs while maintaining hi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $110K *

Unlock potential by leading complex projects within a dynamic ePMO, driving cross-functional alignment, and ensuring timely execution while communicating effectively with senior leadership to foster t...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Help us ensure high-quality decision-making by collaborating with leaders to frame strategies and analyze options, driving impactful decisions that align with organizational goals and values while fos...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Lead the charge in managing and optimizing cloud infrastructure across multiple platforms. Collaborate with teams to enhance product reliability and streamline operations while ensuring security and c...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Discover your potential as you drive enterprise sales in the CPG sector, building relationships with iconic brands. Leverage insights and solutions to develop strategies that enhance client success an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$113K - $226K *

Lead the charge in optimizing healthcare processes by bridging strategy and execution. Collaborate with teams to enhance coding workflows, drive change management, and ensure alignment with strategic...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $180K *

Drive innovative electrical design solutions for high-density compute environments. Collaborate across teams to ensure compliance with industry standards while mentoring junior engineers. Make a signi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Drive innovative software solutions by designing, developing, and testing systems-level software. Collaborate with cross-functional teams to meet operational specifications and enhance SAP functionali...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$75K - $95K *

Join a team that's redefining the annuities landscape by providing innovative solutions. As a key technical advisor, you'll collaborate with clients and internal teams to design impactful solutions th...

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$111K - $211K *

Advance your career by leading impactful research in public health and family planning. Drive data analysis and quality assurance efforts across low- and middle-income countries, collaborating with di...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.