Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$200K - $215K *

Drive the design and deployment of innovative data and AI solutions, leveraging expertise in LLMs, agentic AI, and cloud technologies to enhance business value and ensure compliance with industry stan...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Champion exceptional research outcomes by guiding clients through complex projects. Leverage your expertise in methodology and analysis to deliver actionable insights, while collaborating with cross-f...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Lead solar resource assessments and performance analytics for utility-scale projects. Engage with clients, optimize energy yield, and enhance methodologies while ensuring operational excellence in sol...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$82K - $128K *

Shape data-driven strategies by developing and automating analytics solutions. Collaborate with cross-functional teams to enhance reporting capabilities and optimize operational performance in a dynam...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $210K *

Join a dynamic team to lead AI platform strategy and operations, ensuring seamless access and governance while driving enterprise-wide adoption and continuous improvement of innovative AI solutions...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in optimizing marketing operations to drive developer adoption, pipeline growth, and revenue. Oversee systems, processes, and insights while collaborating with cross-functional teams t...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Transform healthcare delivery by leveraging your Epic Cadence expertise to design, build, and optimize scheduling workflows. Collaborate with teams to ensure successful project outcomes and enhance pa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping federal policy and advocacy. As a Government Affairs Manager, you'll engage with Congress and the Executive Branch, driving strategic initiatives across key domestic issues...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $187K *

Grow your career with a hands-on Engineering Manager role leading a dynamic team to enhance an AI-powered healthcare hiring platform, ensuring quality, reliability, and innovation across multiple tech...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$79K - $112K *

Transform cash forecasting processes by leveraging technology and analytics. Collaborate with Treasury leadership to enhance cash flow insights and automate reporting, ensuring accuracy and efficiency...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $220K *

Elevate your career by leading the design and deployment of innovative AI solutions. Collaborate with strategic customers to tackle complex data challenges, leveraging graph databases and LLMs to deli...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Transform banking analytics by developing and optimizing financial crime detection models. Leverage your expertise in Python and SQL to analyze complex datasets, enhance model performance, and collabo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Unlock potential by driving new enterprise sales in cybersecurity. Own the full sales cycle, from prospecting to closing, while expanding existing accounts. Collaborate with teams to deliver tailored...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$216K - $228K *

Transform the research landscape by defining and leading user research practices that connect customer insights to product design across multiple foundational areas, driving high-quality deliverables...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $180K *

Transform the future of cloud infrastructure by leading DevOps initiatives, enhancing systems integration, and driving innovative solutions for federal clients. Collaborate with stakeholders to optimi...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$215K - $240K *

Shape the future of commercial operations by leading strategy, workflows, and data integration. Collaborate with senior leaders to enhance brand performance and drive operational excellence across cro...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $211K *

Lead the charge in transforming enterprise applications through cloud migration. Drive global initiatives, mentor teams, and solve complex challenges while ensuring seamless transitions to Azure and A...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Empower cross-functional teams to consolidate payment gateways, leveraging deep USA Payments expertise. Collaborate with stakeholders to analyze requirements, drive migrations, and ensure seamless int...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $200K *

Transform client relationships by leading data-driven solutions for major tech firms. Engage with executives to uncover insights, drive impactful decisions, and ensure seamless delivery across teams i...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $140K *

Join a dynamic team as you take ownership of the accounting function, managing spend, payables, and reconciliations. Drive process improvements and leverage AI to enhance workflows, ensuring accuracy...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $185K *

Transform data into actionable insights by enhancing financial models, optimizing sales performance, and driving operational efficiencies. Collaborate with cross-functional teams to support strategic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$163K - $322K *

Champion AI security strategies by leading complex projects, advising executives, and driving governance initiatives. Leverage deep expertise in cybersecurity and risk management to enhance client out...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$115K - $150K *

Architect and streamline cloud network infrastructure. Support robust security and connectivity across Azure, OpenShift, and SASE platforms. Collaborate with cross-functional teams, ensuring optimal p...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$145K - $165K *

Lead the charge in enhancing marketing technology platforms to optimize customer engagement and journey orchestration. Collaborate with cross-functional teams to deliver reliable solutions and improve...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $150K *

Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.