Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Senior Statistical Programmer/Analyst Consultant (Need solid oncology background) Remote in US
$110K - $130K *
Champion statistical programming excellence in oncology clinical trials. Lead programming activities, collaborate with cross-functional teams, and ensure high-quality deliverables from study start-up...
2 weeks ago
AI Delivery Engineer - AWS Bedrock
$135K - $220K *
Engage with clients to transform business challenges into AI solutions. Collaborate in a multidisciplinary team to develop prototypes and integrate AI applications using AWS services, ensuring quality...
2 days ago
$144K - $184K *
Join an innovative engineering team to transform product delivery through AI-driven development, ensuring high standards and compliance while combining product, design, and engineering leadership acro...
Reposted 1 week ago
$150K - $180K *
Drive enterprise sales strategy for innovative agentic products, building relationships with key decision-makers. Collaborate with product and engineering teams to translate customer needs into compel...
2 weeks ago
$135K - $160K *
Unlock your potential as a Lead Data Software Engineer, driving innovative data solutions and leading cross-functional teams to enhance our data infrastructure and ensure scalability and performance a...
4 weeks ago
Senior Business Intelligence Analyst
$135K - $150K *
Join a team that's redefining business intelligence through Power BI. You'll develop impactful reports and dashboards, enhance client-facing platforms, and ensure data integrity while collaborating wi...
1 week ago
Audience Activation Specialist
$80K - $95K *
Join a team that's redefining acquisition marketing by developing advanced segmentation strategies, optimizing campaigns, and enhancing customer engagement to drive conversion rates and maximize ROI...
Yesterday
Head of Technology & Data Partnerships
$195K - $270K *
Transform the technology and data partnership landscape by defining and executing a strategic vision that enhances product innovation, strengthens market positioning, and drives sustainable growth thr...
2 days ago
$110K - $130K *
Engineer critical electrical and mechanical systems for data centers, leading field support, troubleshooting, and reliability improvements while developing operational standards and mentoring teams to...
1 week ago
Application Engineer (Technical Sales) - Defense
$108K - $181K *
Create impactful technical solutions in military electrification projects. Collaborate with defense clients and provide expertise throughout the proposal process, ensuring compliance and mission effec...
Reposted 1 week ago
$240K - $270K *
Join a team that's driving enterprise growth by owning relationships and closing deals. Leverage your expertise to navigate complex sales cycles, build a self-sourced pipeline, and expand accounts whi...
5 days ago
Senior Software Engineer, Enterprise AI
$199K - $210K *
Unlock potential by joining a dynamic team to design and develop scalable AI solutions. Collaborate across disciplines to transform complex challenges into impactful products, driving innovation and e...
5 days ago
Enterprise AI Architecture Manager / Senior Manager
$94K - $293K *
Advance your career by architecting innovative AI solutions, leading engineering teams, and transforming enterprise systems. Drive impactful change while collaborating with clients to bridge technolog...
1 week ago
$90K - $100K *
Unlock potential by delivering innovative robotic solutions, ensuring seamless integration and operational success for customers. Collaborate, troubleshoot, and enhance system performance while provid...
2 weeks ago
$132K - $261K *
Join a team that's transforming workplace technology by leading digital employee experience initiatives, driving strategic recommendations, and enhancing productivity across enterprise environments...
2 weeks ago
$92K - $115K *
Champion client performance by managing Meta ad campaigns, optimizing strategies, and crafting compelling direct-response content to enhance engagement and retention across multiple accounts...
Reposted 1 week ago
$110K - $130K *
Lead supplier quality initiatives to ensure product conformity and drive continuous improvement. Collaborate with cross-functional teams to establish quality standards, manage audits, and enhance supp...
Reposted yesterday
$75K - $95K *
Shape the future of financial solutions by leveraging your technical expertise and consultative skills. Collaborate with clients and internal teams to design impactful solutions that drive business su...
3 weeks ago
Software Engineer III - Full Stack, Angular, Java, AWS
$102K - $136K *
Empower your career by designing and delivering scalable software solutions in a dynamic environment. Collaborate with cross-functional teams to enhance healthcare supply chain products using modern t...
3 weeks ago
Site Inspector Lead (Data Center Manufacturing Quality)
$100K - $120K *
Empower quality assurance excellence by leading inspections across North America, ensuring critical infrastructure meets project standards. Collaborate with suppliers and teams to mitigate risks and d...
2 weeks ago
Digital Demand Generation Manager
$80K - $95K *
Join a dynamic team as you lead digital marketing initiatives, focusing on webinars and paid advertising to drive engagement and generate leads. Collaborate with stakeholders to optimize strategies an...
2 weeks ago
Technical Lead (Data Science and AI/ML)
$125K - $150K *
Empower teams by providing technical leadership in data science and AI/ML, driving enterprise data modernization initiatives. Collaborate with stakeholders to design and deliver impactful decision-mak...
3 weeks ago
$117K - $176K *
Accelerate progress at the forefront of electromechanical design, leading product development for circuit breakers. Collaborate across teams to ensure compliance, quality, and innovation while mentori...
1 week ago
Staff Software Engineer, Applied AI
$160K - $200K *
Join a team that's redefining operational efficiency by architecting robust internal tools and applying AI to real-world challenges. You'll lead technical direction, drive impactful decisions, and enh...
1 week ago
Senior Software Engineer - Grafana Search & Storage | US | Remote
$154K - $185K *
Join our dynamic team to develop next-gen storage solutions, enhancing Grafana's App Platform. Collaborate on innovative features, drive projects from ideation to operations, and contribute to an open...
2 weeks ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.