Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Champion statistical programming excellence in oncology clinical trials. Lead programming activities, collaborate with cross-functional teams, and ensure high-quality deliverables from study start-up...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $220K *

Engage with clients to transform business challenges into AI solutions. Collaborate in a multidisciplinary team to develop prototypes and integrate AI applications using AWS services, ensuring quality...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$144K - $184K *

Join an innovative engineering team to transform product delivery through AI-driven development, ensuring high standards and compliance while combining product, design, and engineering leadership acro...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Drive enterprise sales strategy for innovative agentic products, building relationships with key decision-makers. Collaborate with product and engineering teams to translate customer needs into compel...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$135K - $160K *

Unlock your potential as a Lead Data Software Engineer, driving innovative data solutions and leading cross-functional teams to enhance our data infrastructure and ensure scalability and performance a...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $150K *

Join a team that's redefining business intelligence through Power BI. You'll develop impactful reports and dashboards, enhance client-facing platforms, and ensure data integrity while collaborating wi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Join a team that's redefining acquisition marketing by developing advanced segmentation strategies, optimizing campaigns, and enhancing customer engagement to drive conversion rates and maximize ROI...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$195K - $270K *

Transform the technology and data partnership landscape by defining and executing a strategic vision that enhances product innovation, strengthens market positioning, and drives sustainable growth thr...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Engineer critical electrical and mechanical systems for data centers, leading field support, troubleshooting, and reliability improvements while developing operational standards and mentoring teams to...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$108K - $181K *

Create impactful technical solutions in military electrification projects. Collaborate with defense clients and provide expertise throughout the proposal process, ensuring compliance and mission effec...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$240K - $270K *

Join a team that's driving enterprise growth by owning relationships and closing deals. Leverage your expertise to navigate complex sales cycles, build a self-sourced pipeline, and expand accounts whi...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$199K - $210K *

Unlock potential by joining a dynamic team to design and develop scalable AI solutions. Collaborate across disciplines to transform complex challenges into impactful products, driving innovation and e...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$94K - $293K *

Advance your career by architecting innovative AI solutions, leading engineering teams, and transforming enterprise systems. Drive impactful change while collaborating with clients to bridge technolog...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$90K - $100K *

Unlock potential by delivering innovative robotic solutions, ensuring seamless integration and operational success for customers. Collaborate, troubleshoot, and enhance system performance while provid...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$132K - $261K *

Join a team that's transforming workplace technology by leading digital employee experience initiatives, driving strategic recommendations, and enhancing productivity across enterprise environments...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$92K - $115K *

Champion client performance by managing Meta ad campaigns, optimizing strategies, and crafting compelling direct-response content to enhance engagement and retention across multiple accounts...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead supplier quality initiatives to ensure product conformity and drive continuous improvement. Collaborate with cross-functional teams to establish quality standards, manage audits, and enhance supp...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Energy & Utilities

$75K - $95K *

Shape the future of financial solutions by leveraging your technical expertise and consultative skills. Collaborate with clients and internal teams to design impactful solutions that drive business su...

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$102K - $136K *

Empower your career by designing and delivering scalable software solutions in a dynamic environment. Collaborate with cross-functional teams to enhance healthcare supply chain products using modern t...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Empower quality assurance excellence by leading inspections across North America, ensuring critical infrastructure meets project standards. Collaborate with suppliers and teams to mitigate risks and d...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a dynamic team as you lead digital marketing initiatives, focusing on webinars and paid advertising to drive engagement and generate leads. Collaborate with stakeholders to optimize strategies an...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Empower teams by providing technical leadership in data science and AI/ML, driving enterprise data modernization initiatives. Collaborate with stakeholders to design and deliver impactful decision-mak...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$117K - $176K *

Accelerate progress at the forefront of electromechanical design, leading product development for circuit breakers. Collaborate across teams to ensure compliance, quality, and innovation while mentori...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Join a team that's redefining operational efficiency by architecting robust internal tools and applying AI to real-world challenges. You'll lead technical direction, drive impactful decisions, and enh...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$154K - $185K *

Join our dynamic team to develop next-gen storage solutions, enhancing Grafana's App Platform. Collaborate on innovative features, drive projects from ideation to operations, and contribute to an open...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.