Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$124K - $169K *

Optimize cross-portfolio analytics to enhance Gross-to-Net performance, identify anomalies, and drive process improvements. Collaborate with diverse teams to deliver actionable insights and scalable r...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Empower your career by leading innovative GTM engineering initiatives. Drive AI workflows, automate marketing processes, and enhance productivity across teams. Collaborate with stakeholders to transfo...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Lead the design and implementation of scalable ML systems, bridging business strategy with technical execution. Drive impactful data solutions, mentor teams, and ensure robust model performance to enh...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$105K - $160K *

Drive customer success by optimizing digital journeys and automating solutions. Collaborate cross-functionally to enhance user experiences while leveraging AI and coding skills to maintain and deploy...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $252K *

Transform operations by leading strategic data labeling initiatives, collaborating with cross-functional teams to optimize workflows and integrate advanced technologies, ensuring scalable and efficien...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Media

$83K - $138K *

Join our team as a Senior Revenue Accountant to enhance global revenue assurance, ensuring compliance with ASC 606 while collaborating with cross-functional teams to drive operational consistency and...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by driving customer success through strategic relationships and exceptional service. Collaborate cross-functionally to enhance product adoption and ensure client satisfaction, ultimat...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's dedicated to enhancing customer satisfaction by driving product adoption and delivering exceptional service. You'll build strong relationships with clients, ensuring they achieve th...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $130K *

Partner with us to deliver strategic financial insights that drive business success through effective forecasting, budgeting, and performance analysis, enabling informed decision-making and enhancing...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $140K *

Champion growth by driving new revenue through strategic enterprise account management. Leverage your expertise to build relationships, maximize conversion rates, and close complex deals in a dynamic...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$171K - $214K *

Join us to lead the design and oversight of complex models driving customer lifetime value. Collaborate with engineers and business teams to enhance decision-making across marketing, finance, and prod...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$101K - $145K *

Lead the charge in leveraging advanced data science techniques to solve complex business challenges, mentor junior team members, and drive effective risk management through innovative algorithms and d...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Drive the technical design and delivery of innovative AI agent solutions, leading a team to ensure operational readiness and quality. Collaborate with stakeholders to define requirements and guide eng...

RemoteRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $175K *

Empower financial analysis and project management in the utility sector. Lead cost-of-service studies, develop client relationships, and mentor junior staff while ensuring quality and timely delivery...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$193K - $340K *

Lead analytics initiatives to empower strategic decisions in a fast-growing agent business. Drive insights, build foundational data systems, and foster a high-performing team to enhance user experienc...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$70K - $95K *

Unlock potential by leveraging data insights to drive scalable growth and enhance sales team performance. Collaborate with leadership to develop strategies that improve productivity and operational ef...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Transportation

$156K - $181K *

Unlock potential by driving enterprise risk management through advanced analytics and reporting solutions. Collaborate with stakeholders to enhance decision-making and operational effectiveness while...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Lead a talented team in crafting a high-quality, scalable object storage product that enhances the developer experience, balancing technical execution with product thinking to drive meaningful improve...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Champion innovative data solutions by architecting scalable cloud data pipelines and lakes. Leverage deep financial services expertise to drive technical product management and ensure seamless data in...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Advance your career by driving impactful Paid Social strategies across platforms like Meta and TikTok. Collaborate with cross-functional teams to optimize campaigns, leverage data insights, and enhanc...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$130K - $200K *

Transform client interactions by designing innovative AI-driven conversational experiences, leading projects that integrate multi-agent systems and omnichannel strategies to enhance user engagement an...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Join a team that's dedicated to driving financial excellence through detailed analysis, reporting, and strategic recommendations. Collaborate with leadership to enhance financial performance and suppo...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $135K *

Elevate your career by leading enterprise data and AI governance initiatives. Collaborate across teams to define frameworks, implement policies, and drive adoption of responsible AI practices, ensurin...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$140K - $165K *

Lead comprehensive demand generation efforts by managing campaigns, events, and HubSpot systems to enhance pipeline efficiency. Influence strategy and execution for paid media, thereby driving measura...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $220K *

Engage with clients to transform business challenges into AI solutions. Collaborate in a multidisciplinary team to develop prototypes and integrate AI applications using AWS services, ensuring quality...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.