Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Account Executive - Business Development Sales, Healthcare SaaS
$150K - $180K *
Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...
1 week ago
$192K - $240K *
Empower innovation as you lead complex AI system design and delivery, influencing architecture and engineering practices. Collaborate across teams to ensure scalable, high-quality solutions with signi...
Reposted 2 weeks ago
$90K - $110K *
Grow your career with a dynamic team focused on generating new business in the public sector. Utilize a consultative sales approach to build relationships and deliver tailored solutions, driving reven...
1 week ago
$80K - $95K *
Partner with us to enhance clinical IT solutions as an Epic Analyst II, providing critical support, training, and implementation for Epic EHR systems. Collaborate with teams to optimize workflows and...
3 weeks ago
$150K - $160K *
Champion cloud and application security by enhancing AWS practices, collaborating with cross-functional teams, and driving continuous improvement to ensure secure and compliant environments...
Reposted 5 days ago
$73K - $220K *
Architect innovative mobile solutions, leading a team to enhance client productivity and collaboration through strategic application development across multiple platforms...
3 weeks ago
Engineering Manager, Software Engineering (Java Backend)
$120K - $170K *
Join a team that's transforming digital services for Veterans by leading a skilled engineering group. You'll balance hands-on technical leadership with mentoring, driving the development of scalable J...
Yesterday
$125K - $150K *
Drive strategic tracking engagements by providing expert guidance and oversight. Collaborate with clients and teams to ensure high-quality outcomes, effective communication, and successful project exe...
3 weeks ago
$105K - $140K *
Contribute to the evolution of cloud platform capabilities by designing and building backend services for orchestration and job execution, ensuring reliable service coordination and operational visibi...
4 weeks ago
$86K - $137K *
Optimize project outcomes as you manage small to medium-sized initiatives. Collaborate across teams, navigate risks, and ensure timely delivery of quality solutions while enhancing communication and s...
Reposted 1 week ago
$80K - $95K *
Elevate your career by managing and optimizing multi-platform paid social campaigns. Leverage data-driven insights to enhance client ROI while collaborating with creative teams and leading strategic i...
2 days ago
Analyst, Manufacturing IT/OT Systems
$80K - $95K *
Join a team that's transforming manufacturing by integrating cutting-edge IT systems. You'll collaborate globally to enhance production efficiency, safety, and sustainability, making a significant imp...
1 week ago
Information Security Architect - AI
$170K - $212K *
Elevate AI security by designing robust frameworks to protect systems from threats. Collaborate with cross-functional teams to ensure compliance and ethical use, while implementing strategies that saf...
4 weeks ago
Avionics/ Staff Command and Data Handling Engineer
$117K - $195K *
Join a team that's developing cutting-edge avionics architectures for diverse missions. Leverage your expertise in command and data handling to optimize system performance and ensure seamless integrat...
4 weeks ago
Data Mining Specialist (Payment Integrity)
$93K - $134K *
Drive impactful data mining initiatives by analyzing complex claims across Medicare, Medicaid, and Commercial sectors. Leverage your expertise to identify anomalies and enhance recovery opportunities...
1 week ago
Transformation Consultant, Professional Services
$74K - $137K *
Lead the charge in transforming workflows with AI, driving adoption and measurable impact in legal, tax, and trade sectors. Collaborate with clients and teams to design, implement, and evaluate innova...
3 weeks ago
Senior Software Engineer - Data Infrastructure
$175K - $200K *
Optimize our data infrastructure platform by enhancing automation, observability, and stability. Drive architectural changes to support long-term service requirements while ensuring high throughput an...
2 weeks ago
$110K - $130K *
Transform search visibility and traffic by leading SEO initiatives across diverse domains. Collaborate cross-functionally to optimize content, diagnose technical issues, and leverage data for impactfu...
4 weeks ago
$70K - $196K *
Innovate cloud solutions by designing reusable architectures and supporting client delivery. Collaborate with teams to enhance AWS implementations, ensuring quality and efficiency while staying curren...
1 week ago
Software Engineer, Infrastructure Engineering
$164K - $229K *
Elevate infrastructure reliability and performance by architecting scalable solutions, collaborating across teams, and driving end-to-end software delivery to enhance user experience and system resili...
Reposted today
$88K - $154K *
Optimize and integrate the manufacturing process for hazardous materials, taking ownership from design through commissioning. Collaborate with multidisciplinary teams to ensure safety and efficiency i...
Reposted 1 week ago
Vice President, Decision Science
$160K - $220K *
Join us to lead and expand our Analytics practice, driving data insights and marketing strategies while managing a talented team in a dynamic and evolving digital landscape...
Reposted today
Manager, Procurement Compliance, Governance and Data & Analytics
$110K - $172K *
Shape global procurement governance and compliance by leading analytics, training, and process excellence initiatives. Drive transformation and data management in a collaborative environment to enhanc...
2 weeks ago
CCaR - Senior Software Engineer (Remote)
$140K - $160K *
Drive the development of critical enterprise applications for DoD personnel, enhancing program and financial management capabilities. Collaborate within a product team to modernize technology and deli...
1 week ago
Business Development Associate
$70K - $96K *
Empower your career by joining our dynamic team to drive client engagement, identify opportunities, and develop innovative sales strategies. Collaborate with stakeholders and enhance your skills in a...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.