Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$150K - $180K *

Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$192K - $240K *

Empower innovation as you lead complex AI system design and delivery, influencing architecture and engineering practices. Collaborate across teams to ensure scalable, high-quality solutions with signi...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $110K *

Grow your career with a dynamic team focused on generating new business in the public sector. Utilize a consultative sales approach to build relationships and deliver tailored solutions, driving reven...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $95K *

Partner with us to enhance clinical IT solutions as an Epic Analyst II, providing critical support, training, and implementation for Epic EHR systems. Collaborate with teams to optimize workflows and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $160K *

Champion cloud and application security by enhancing AWS practices, collaborating with cross-functional teams, and driving continuous improvement to ensure secure and compliant environments...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$73K - $220K *

Architect innovative mobile solutions, leading a team to enhance client productivity and collaboration through strategic application development across multiple platforms...

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $170K *

Join a team that's transforming digital services for Veterans by leading a skilled engineering group. You'll balance hands-on technical leadership with mentoring, driving the development of scalable J...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Drive strategic tracking engagements by providing expert guidance and oversight. Collaborate with clients and teams to ensure high-quality outcomes, effective communication, and successful project exe...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Media

$105K - $140K *

Contribute to the evolution of cloud platform capabilities by designing and building backend services for orchestration and job execution, ensuring reliable service coordination and operational visibi...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$86K - $137K *

Optimize project outcomes as you manage small to medium-sized initiatives. Collaborate across teams, navigate risks, and ensure timely delivery of quality solutions while enhancing communication and s...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Elevate your career by managing and optimizing multi-platform paid social campaigns. Leverage data-driven insights to enhance client ROI while collaborating with creative teams and leading strategic i...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$80K - $95K *

Join a team that's transforming manufacturing by integrating cutting-edge IT systems. You'll collaborate globally to enhance production efficiency, safety, and sustainability, making a significant imp...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$170K - $212K *

Elevate AI security by designing robust frameworks to protect systems from threats. Collaborate with cross-functional teams to ensure compliance and ethical use, while implementing strategies that saf...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$117K - $195K *

Join a team that's developing cutting-edge avionics architectures for diverse missions. Leverage your expertise in command and data handling to optimize system performance and ensure seamless integrat...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$93K - $134K *

Drive impactful data mining initiatives by analyzing complex claims across Medicare, Medicaid, and Commercial sectors. Leverage your expertise to identify anomalies and enhance recovery opportunities...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$74K - $137K *

Lead the charge in transforming workflows with AI, driving adoption and measurable impact in legal, tax, and trade sectors. Collaborate with clients and teams to design, implement, and evaluate innova...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$175K - $200K *

Optimize our data infrastructure platform by enhancing automation, observability, and stability. Drive architectural changes to support long-term service requirements while ensuring high throughput an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Transform search visibility and traffic by leading SEO initiatives across diverse domains. Collaborate cross-functionally to optimize content, diagnose technical issues, and leverage data for impactfu...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$70K - $196K *

Innovate cloud solutions by designing reusable architectures and supporting client delivery. Collaborate with teams to enhance AWS implementations, ensuring quality and efficiency while staying curren...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$164K - $229K *

Elevate infrastructure reliability and performance by architecting scalable solutions, collaborating across teams, and driving end-to-end software delivery to enhance user experience and system resili...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Media

$88K - $154K *

Optimize and integrate the manufacturing process for hazardous materials, taking ownership from design through commissioning. Collaborate with multidisciplinary teams to ensure safety and efficiency i...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $220K *

Join us to lead and expand our Analytics practice, driving data insights and marketing strategies while managing a talented team in a dynamic and evolving digital landscape...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Media

$110K - $172K *

Shape global procurement governance and compliance by leading analytics, training, and process excellence initiatives. Drive transformation and data management in a collaborative environment to enhanc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$140K - $160K *

Drive the development of critical enterprise applications for DoD personnel, enhancing program and financial management capabilities. Collaborate within a product team to modernize technology and deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $96K *

Empower your career by joining our dynamic team to drive client engagement, identify opportunities, and develop innovative sales strategies. Collaborate with stakeholders and enhance your skills in a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.