Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$108K - $160K *

Optimize data integration and analysis for supply chain decisions, focusing on parts, procurement, and risk data. Collaborate with experts to identify constraints and enhance workflows, ensuring trace...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Join a team that's advancing national security by securing our infrastructure. Work collaboratively in a dynamic environment to enhance IT engineering efforts, ensuring compliance and safeguarding cru...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$145K - $170K *

Pioneer innovative research at the intersection of AI and cybersecurity, tackling real-world security challenges. Collaborate with diverse teams to develop prototypes and experiments that influence cu...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$190K - $220K *

Champion robust data integration while collaborating with cross-functional teams to design and optimize data pipelines, directly influencing our rapidly scaling marketing intelligence platform's succe...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Transform the landscape of programmatic media sales by driving new business with mid-sized agencies. Leverage first-party data solutions to enhance marketing strategies and build lasting relationships...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Transform your career by leading platform engineering initiatives that enhance developer experience and operational excellence. Drive technical ownership across the software lifecycle, shaping the pla...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$172K - $229K *

Join a dynamic team to enhance autonomous vehicle performance through innovative software tools and metrics. Collaborate cross-functionally to drive technical strategy and ensure data quality, contrib...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Transportation

$130K - $155K *

Unlock potential by leading the design and development of enterprise applications using C# and .NET, driving modern software practices, and collaborating with cross-functional teams to implement secur...

RemoteRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Information Technology

$144K - $170K *

Champion innovative AI security solutions by driving enterprise sales in New England. Leverage your expertise to build relationships, uncover customer needs, and exceed revenue targets in a fast-paced...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $125K *

Join a team that's redefining web development by building innovative applications. Leverage your full-stack expertise in JavaScript and Python while managing cloud infrastructure and data pipelines to...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$275K - $350K *

Lead the charge in building a subscription research business, driving sales and market strategy across energy, trading, and institutional sectors. Collaborate with analysts to tailor offerings and est...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $120K *

Help us accelerate progress by supporting project managers in delivering financial analyses and technical reports, while collaborating with a dynamic team to drive impactful solutions in utility finan...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$129K - $253K *

Champion automation excellence by leading a team to design and implement robust automation strategies, ensuring reliability and security across systems while driving innovation in cloud and applicatio...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$199K - $270K *

Shape the future of software development by enhancing tooling, CI/CD, and operational workflows, ensuring teams can seamlessly transition code changes into production with improved speed, quality, and...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Information Technology

$145K - $170K *

Join a dynamic eCommerce team to enhance the online booking experience. Lead complex features in a Next.js and TypeScript application, impacting conversion and patient trust across multiple countries...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$185K - $215K *

Take ownership of analytical development initiatives, ensuring compliance, accuracy, and high-quality documentation for multiple projects. Collaborate closely with internal teams and external partners...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $102K *

Optimize automation and control systems for safe, reliable operations. Collaborate with field teams to troubleshoot, maintain, and enhance PLCs, HMIs, and instrumentation, ensuring efficient performan...

5 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$88K - $105K *

Optimize automation and control systems for safe, reliable operations at compressor stations. Collaborate with field teams to troubleshoot, maintain, and enhance systems, ensuring efficient performanc...

5 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$135K - $160K *

Join a dynamic team as a Senior Customer Success Architect, focusing on AI adoption. Lead complex engagements, design tailored solutions, and drive measurable outcomes for enterprise clients, bridging...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$131K - $228K *

Empower innovation by developing and optimizing radar perception systems for autonomous agricultural technology. Collaborate across hardware and software to enhance sensor fusion and ensure robust per...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $200K *

Lead the charge in developing integrated media strategies and client partnerships across pharmaceutical and life sciences accounts, driving business growth and ensuring exceptional delivery and client...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $130K *

Champion the modernization of data processes by designing and maintaining robust data pipelines in Azure. Collaborate with stakeholders to ensure accurate data integration and support enterprise data...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$78K - $131K *

Contribute to the development and administration of competitive compensation programs, ensuring alignment with organizational strategy. Lead projects and provide consultation to HR partners while main...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Champion the vision and strategy for AI-powered products, driving their roadmap and delivery while mentoring peers. Leverage AI tools to enhance decision-making and product lifecycle management, ensur...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $175K *

Transform investment research by evaluating and integrating diverse datasets, enhancing AI-driven workflows, and driving strategic content initiatives to elevate platform value and user experience...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.