Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$95K - $115K *

Elevate engineering processes by developing innovative software and AI solutions. Collaborate with a dynamic team to transform concepts into scalable applications, leveraging modern web technologies a...

Reposted today

  •   Less than 5 years exp.  •   Staffing

$130K - $155K *

Join a team that's redefining travel analytics by leveraging data to empower partners. As a Senior Data Scientist, you'll drive insights, automate reporting, and enhance decision-making across diverse...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$183K - $206K *

Transform AI observability by developing end-to-end capabilities, architecting data models, and collaborating with cross-functional teams to enhance user workflows and insights into agent performance...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$73K - $131K *

Drive analytics excellence by managing a team that transforms data into actionable insights, optimizing strategic decisions and enhancing operational efficiency across the business unit...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$85K - $90K *

Empower customers through innovative strategies and data insights in digital advertising. Establish scaled success and deep relationships within the Ads portfolio, setting new standards for retention...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $200K *

Develop and maintain robust data pipelines and models, collaborating with cross-functional teams to enhance data practices and ensure quality. Drive modernization efforts in data engineering, optimizi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $135K *

Tackle the full sales cycle by winning new logos and expanding accounts. Drive pipeline growth through outbound prospecting and inbound leads, while shaping go-to-market strategies in a dynamic, remot...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $95K *

Join a team that's driving innovation in mobile advertising by managing fraud mitigation and partner relationships. Leverage your expertise in advertising measurement to navigate the dynamic landscape...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Media

$120K - $145K *

Help us drive technical strategy and solutions for enterprise clients, addressing security challenges and delivering impactful demonstrations. Collaborate with cross-functional teams to translate comp...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$140K - $190K *

Grow your career with a dynamic team leading innovative ad experiences. Drive product strategy through data-driven decisions while managing a cross-functional squad focused on quality and user trust i...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Join a dynamic team to design and optimize data pipelines, ensuring quality and security for analytics and AI capabilities. Collaborate with cross-functional teams to deliver innovative data solutions...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Shape the future of pricing strategy by analyzing proposals, developing cost models, and ensuring compliance with federal regulations. Collaborate with cross-functional teams to enhance competitive po...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Information Technology

$94K - $273K *

Redefine enterprise AI solutions by designing and deploying agentic systems that scale across diverse cloud-native environments while collaborating directly with clients to ensure seamless implementat...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Business Services

$94K - $316K *

Unlock potential by designing and deploying AI agents that enhance enterprise workflows. Collaborate closely with clients to integrate advanced technologies into existing systems, ensuring robust and...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Business Services

$151K - $241K *

Develop and optimize AI solutions for enhanced member experiences, integrating cutting-edge technologies and engineering practices. Collaborate with cross-functional teams to ensure reliable, scalable...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$194K - $259K *

Innovate data solutions by building robust models and pipelines, translating business needs into technical specifications, and mentoring junior engineers to enhance data engineering practices and code...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $90K *

Advance quality assurance initiatives and optimize workflows in a remote healthcare contact center. Collaborate cross-functionally to enhance compliance, improve patient outcomes, and drive continuous...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$171K - $269K *

Lead the charge in defining and evolving data architecture and engineering standards for scalable, secure enterprise data platforms. Collaborate across teams to deliver reliable, actionable data produ...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Join a team that's redefining enterprise data management by leading cross-functional initiatives, ensuring data reliability, and driving strategic insights through advanced program management and tech...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $145K *

Join a dynamic team to design, develop, and maintain full-stack applications, leveraging Python, AWS, and Terraform. Lead projects from ideation to deployment while mentoring junior engineers and ensu...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Join a dynamic team to enhance application security across web apps, APIs, and cloud services. Collaborate with development squads to prioritize vulnerabilities and implement proactive remediation str...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Transform application security practices by enhancing web, API, and cloud service protections. Collaborate with development teams to remediate vulnerabilities and integrate security into CI/CD workflo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Champion the management and execution of complex e-discovery projects, collaborating with legal teams to ensure successful outcomes. Oversee multiple projects while mentoring a team, maintaining quali...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$115K - $145K *

Transform business operations by developing and deploying AI solutions that enhance product capabilities and customer experiences. Collaborate with cross-functional teams to integrate machine learning...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Engineer seamless integrations and automation across systems, enhancing operational efficiency and collaboration. Leverage your expertise in SaaS platforms and APIs to drive innovative solutions in a...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.