Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$130K - $155K *

Join a team that's redefining retail technology by leading a high-performing engineering group focused on modernizing and automating store platforms for a global audience, ensuring reliability and sca...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$130K - $155K *

Empower your career by leading DevOps initiatives, optimizing cloud infrastructure, and driving Agile practices. Collaborate with cross-functional teams to enhance scalability, security, and cost effi...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$172K - $203K *

Tackle complex reliability challenges in consumer hardware by building data-driven models and systems. Collaborate cross-functionally to enhance product quality and performance, leveraging advanced an...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $110K *

Transform enterprise modernization by leading user-centered design and business analysis initiatives. Collaborate with stakeholders to optimize workflows, enhance user experiences, and drive strategic...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$199K - $276K *

Drive enhancements to our unsecured underwriting models through rigorous research and experimentation. Collaborate with engineering teams to translate findings into scalable solutions that improve cre...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Join a dynamic team to lead connectivity projects for leased data centers, ensuring compliance with standards and managing cross-functional collaboration from site assessment to operational handoff. D...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $180K *

Transform digital healthcare services by designing and deploying scalable machine learning models. Collaborate with cross-functional teams to enhance predictive capabilities and ensure compliance with...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $115K *

Partner with us to enhance client engagement and product success by leveraging your analytical skills and industry insights. Collaborate cross-functionally to drive improvements and support user adopt...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$100K - $125K *

Champion data engineering excellence by designing and maintaining robust data pipelines and analytics solutions. Collaborate with stakeholders to enhance data quality and support enterprise-level data...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $140K *

Transform your career by driving impactful sales playbooks and incentive programs. Leverage Salesforce, SQL, and AI tools to automate processes and enhance pipeline generation in a collaborative, glob...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$9K - $185K *

Lead the optimization of large-scale SQL Server databases, enhancing performance and efficiency. Drive data mining capabilities by resolving bottlenecks and implementing innovative solutions that dire...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$108K - $148K *

Join us as a Senior FP&A Analyst to drive financial planning, reporting, and forecasting. Collaborate across teams to optimize spending and enhance our financial systems, leveraging AI for insights th...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Optimize energy solutions by leading technical projects, conducting site surveys, and collaborating with teams to deliver innovative, cost-effective strategies that enhance facility performance and su...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $145K *

Empower clinical trial design by architecting robust data infrastructures that streamline insights extraction from diverse clinical documents, enhancing decision-making through advanced data pipelines...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$104K - $156K *

Join us to architect innovative financial systems, leading greenfield projects that enhance data management and analytics. Collaborate across teams to implement your vision and drive impactful solutio...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $137K *

Unlock your potential as you drive secure automation for cloud migrations, developing infrastructure as code and CI/CD pipelines. Collaborate with teams to enhance processes and ensure compliance whil...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$270K - $300K *

Elevate your career by owning a territory for enterprise accounts, driving complex sales cycles, and building AI solutions. Collaborate with cross-functional teams to deliver value and scale innovativ...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$85K - $165K *

Champion safety in innovative nuclear fuel recycling by evaluating hazards, developing safety documents, and ensuring compliance with regulations. Collaborate in a dynamic team to enhance safety measu...

RemoteRemote

1 month ago

  •   Less than 5 years exp.  •   Energy & Utilities

$135K - $160K *

Empower our data platform by designing, building, and operating core capabilities. Collaborate with teams to enhance ingestion, storage, and API functionalities, ensuring scalability and resilience wh...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Transform healthcare data by designing and implementing scalable knowledge graph solutions. Collaborate with cross-functional teams to ensure robust technical implementations and optimize graph querie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $175K *

Optimize data analytics support for lab production operations by leading a dedicated team in a dynamic environment. Drive innovation, ensure compliance, and enhance operational effectiveness while mak...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$114K - $182K *

Analyze competitive landscapes in ITDC technologies, providing strategic insights and support across functions to enhance market positioning and respond to emerging threats effectively...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$59K - $177K *

Unlock your potential by leading complex digital forensic investigations and developing AI-driven tools. Collaborate with clients and teams to enhance incident response and streamline workflows, ensur...

2 days ago

  •   Less than 5 years exp.  •   Business Services

$174K - $250K *

Drive your career forward by partnering with executives to shape AI strategies, lead complex architecture discussions, and deliver tailored solutions that enhance enterprise AI ecosystems and revenue...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $170K *

Lead a high-output data science team, driving end-to-end project delivery and technical direction. Engage deeply in data engineering, governance, and production model delivery while collaborating with...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.