Twist Bioscience

Technical Project Manager

Twist Bioscience$164K — $203K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • B.S. or M.S. in Molecular Biology, Biochemistry, Chemistry, or related field (Associates degree with relevant experience may be considered)
  • Hands-on experience with molecular biology techniques like PCR, DNA purification, quantification, and library preparation
  • Experience in a lab environment with a focus on detail and documentation
  • Strong multitasking and prioritization skills in a fast-paced setting
  • Excellent organizational, planning, and problem-solving abilities
  • Interpersonal and communication skills with a collaborative approach
  • Self-motivated and dedicated to delivering high-quality outcomes.

Responsibilities

  • Execute NGS library preparation, target enrichment, and sequencing workflows as per protocols
  • Process samples for NGS analysis adhering to production schedules and customer deadlines
  • Perform basic molecular biology techniques including PCR/qPCR, DNA quantification, purification, and electrophoresis
  • Operate and maintain lab equipment such as liquid handling robots and sequencing platforms
  • Troubleshoot experimental and equipment-related issues to ensure workflow continuity
  • Manage and document multiple projects and samples accurately and in detail
  • Analyze experimental data and contribute to the interpretation of results.

Benefits

  • Eligible for bonus and equity opportunities
  • Generous benefits package
  • Base cash compensation commensurate with experience
Full Job Description
Twist Bioscience is seeking a highly motivated and detail-oriented individual to support customer-driven Next Generation Sequencing (NGS) projects within a fast-paced, service laboratory. This role will work cross-functionally with Sales, R&D, Field Applications, and Customer Support teams to deliver high-quality sequencing data and solutions. The ideal candidate thrives in a dynamic environment, is highly organized, and is committed to maintaining production timelines while ensuring scientific excellence.
What You'll Be Doing
  • Execute NGS library preparation, target enrichment, and sequencing workflows according to established protocols
  • Process samples for NGS analysis while meeting production schedules and customer timelines
  • Perform routine molecular biology techniques including PCR/qPCR, DNA quantification, purification (e.g., SPRI), and electrophoresis
  • Operate and maintain laboratory equipment, including liquid handling robots and sequencing platforms
  • Troubleshoot experimental and equipment-related issues to ensure continuity of workflows
  • Track multiple projects and samples simultaneously, ensuring accurate and detailed documentation (including batch records and deviations)
  • Analyze experimental data and contribute to interpretation of results
  • Support development, optimization, and execution of NGS-related protocols and workflows
  • Maintain digital files and records associated with sequencing runs
  • Ensure compliance with regulatory standards (e.g., ISO 13485) and internal quality requirements
  • Support general lab operations including cleaning, restocking, and maintaining a well-organized workspace
  • Collaborate effectively with cross-functional teams under aggressive timelines
What You'll Bring to the Team
  • B.S. or M.S. in Molecular Biology, Biochemistry, Chemistry, or a related field (Associates degree with relevant experience may be considered)
  • Hands-on experience in molecular biology techniques such as PCR, DNA purification, quantification, and library preparation
  • Experience working in a laboratory environment with strong attention to detail and documentation practices
  • Ability to manage multiple tasks and prioritize effectively in a fast-paced environment
  • Strong organizational, planning, and problem-solving skills
  • Excellent interpersonal and communication skills with a collaborative mindset
  • Self-motivated with a commitment to delivering high-quality results
Preferred Qualifications
  • 3-5 years of experience in molecular biology, NGS workflows, or a related field
  • Direct experience with NGS platforms (e.g., Illumina, PacBio, Element, ONT) and associated sample preparation workflows
  • Experience with NGS library preparation and target enrichment workflows
  • Experience with a range of NGS applications DNA, RNA, and Methylation assays
  • Strong familiarity with analytical tools such as BioAnalyzer or TapeStation, Qubit fluorometry and Nanodrop spectrophotometry


The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

San Francisco Bay Area Pay Range

$164,000-$203,000 USD

About Twist Bioscience

Twist Bioscience Corporation is a biotechnology company that develops and produces synthetic DNA and RNA. The company's platform allows for the rapid and cost-effective production of custom DNA and RNA sequences, which can be used in a variety of applications such as drug discovery, diagnostics, and data storage. Twist Bioscience's customers include academic and research institutions, pharmaceutical and biotechnology companies, and government agencies. The company was founded in 2013 and is headquartered in San Francisco, California.
Learn more about Twist Bioscience
Size
652 employees
Market Cap
$1.2 billion
Industry
Net Income
-$117.1 million
Founded
2013
5 Year Trend
+80%
Revenue
$101.1 million
NASDAQ

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