Mayo Clinic

Senior Software Engineer - AI Platform Engineering

Mayo Clinic$120K — $150K *
Information Technology
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or Associate's degree in Computer Science/Engineering or related field with relevant experience.
  • 5-7 years of professional experience in software engineering, with a focus on AI/ML.
  • Proficiency in coding with high-level languages, particularly Python.
  • Experience with containerization and orchestration tools, preferably Kubernetes.
  • Strong knowledge of observability practices in distributed systems.

Responsibilities

  • Design and implement high-performance hosting environments for models and agents.
  • Build multi-tenant platform capabilities for seamless execution across cloud and on-prem environments.
  • Implement solutions for real-time monitoring and automated evaluation of AI agents and models.
  • Ensure platform reliability as part of the operational team responsible for critical AI services.
  • Collaborate with cross-functional teams to identify system friction and streamline workflows.

Benefits

  • Work on cutting-edge AI and hybrid-cloud technology.
  • Contribute to the foundational infrastructure for autonomous AI agents.
  • Engage with a team focused on performance and governance in high-stakes environments.
Full Job Description
Job Description

The Role

As a Senior Software Engineer for AI Platform Engineering, you will bridge the gap between high-scale systems architecture and frontier AI. You will be one of architects and builders of our Model & Agent Runtimes-the specialized engines that govern how models and autonomous agents execute across our hybrid-cloud footprint.

This isn't just about deployment; it's about a platform-first mindset. You will ensure that AI capabilities are scalable, secure, and governed through world-class AgentOps, LLMOps, and MLOps practices.

What You'll Do
  • Architect the Future of Runtimes: Design and implement high-performance hosting environments for both specialized models and autonomous agents.
  • Scale Hybrid-Cloud Infrastructure: Build multi-tenant platform capabilities that support seamless agent and model execution across diverse cloud and on-prem environments.
  • Drive Operational Excellence: Implement robust solutions for real-time monitoring, distributed tracing, and automated evaluation of agents & models in production.
  • Operational Stewardship: Act as a member of our rotational platform operational team, ensuring the reliability and uptime of critical AI services.
  • Collaborate & Advocate: Partner with cross-functional AI teams to identify system friction, streamlining their workflows and accelerating the delivery of AI-driven value.


What You'll Bring
  • Deep Systems Expertise: Proven experience building scalable back-end systems, ideally with a focus on containerization and orchestration (Kubernetes).
  • AI/ML Fluency: Strong understanding of the lifecycle of LLMs and autonomous agents, including inference optimization and RAG architectures.
  • Operational Rigor: A track record of implementing observability (logging, metrics, tracing) in complex, distributed environments.
  • Problem-Solving Mindset: The ability to turn abstract AI research into production-grade, hardened platform features.


Why this team? We are moving beyond simple model serving. We are building the foundational "nervous system" for autonomous agents in a high-stakes environment where performance and governance are non-negotiable.

This vacancy is not eligible for sponsorship/ we will not sponsor or transfer visas for this position. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.

Qualifications

Required qualifications for this position include: Bachelor's Degree in Computer Science/Engineering or related field with 5 years of experience as noted below; OR an Associate's degree in Computer/Science/Engineering or related field with 7 years of experience.

Have in-depth knowledge of software engineering with experience coding applications or services in a high-level programming language, preferably Python, and a basic knowledge of related fields.
Demonstrated problem solving and time management skills. Possesses strong technical aptitude for designing and implementing software solutions. Experience with modern application development frameworks
Knowledge of professional software engineering practices & best practices for the full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations. Deep hands-on technical expertise, excellent verbal and written communication skills. Experience with Agile software development techniques.
• Preferred qualifications for this position include:
• Master's degree in Computer Science/Engineering or related field.
• Ability to use a wide variety of open-source technologies and cloud-based services.
• Experience writing software for the cloud (GCP, AWS, Azure).
• Experience in databases, analytics, big data systems or business intelligence products.
• Experience building high-performance, highly available and scalable distributed systems.
• Experience developing software for healthcare related industries.

About Mayo Clinic

Mayo Clinic is a nonprofit academic medical center based in Rochester, Minnesota, focused on integrated clinical practice, education, and research. It employs more than 4,500 physicians and scientists and 58,400 administrative and allied health staff. The practice specializes in treating difficult cases through tertiary care and destination medicine. It is home to the Mayo Clinic College of Medicine and Science, which includes a medical school and research programs. Mayo Clinic has a large presence in three U.S. metropolitan areas: Rochester, Minnesota; Jacksonville, Florida; and Phoenix, Arizona. It also has several affiliated hospitals and clinics elsewhere in the United States and around the world.
Learn more about Mayo Clinic
Size
74,000 employees
Industry
Founded
1919

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