About the Role: The Senior Scientist, Pharmacology will be a hands-on scientific leader within Arbor's neuroscience gene-editing programs, driving the strategy, design, execution, and interpretation of in vivo pharmacology studies. Reporting to the Associate Director, In Vivo Pharmacology, this person will collaborate across functions and with external CRO partners to generate decision-enabling data that support advancement of neuroscience programs. This role is based in our Cambridge office, with an expectation of on-site presence 4-5 days per week.
What You Can Expect:- Serve as pharmacology lead in cross-functional nonclinical teams
- Design and execute in vivo pharmacology studies for neuroscience gene-editing programs
- Analyze and interpret in vivo gene editing data, including molecular biology and histology readouts
- Manage 1-2 research associates, providing scientific guidance, prioritizing work, and supporting their development
- Prepare study reports and summaries for regulatory filings
- Oversee CRO studies to ensure high-quality, timely deliverables
What You Bring: Required qualifications- PhD or equivalent degree in Pharmacology, Neuroscience, Genetic Medicine, Biomedical Sciences, or a related field
- 2-5 years of industry experience designing, managing, and interpreting in vivo pharmacology studies for neuroscience indications
- Experience with AAV-based therapeutic programs
- Expertise in molecular readouts, including DNA-, RNA-, and/or protein-based assays
- Experience overseeing outsourced studies, collaborating with CRO partners, and ensuring high-quality, timely deliverables
- Experience managing or mentoring junior scientists or research associates
- Experience preparing study reports or summaries to support regulatory filings
- Ability to work independently and collaboratively in a fast-paced, matrixed team environment
- Strong planning, organization, time management, communication, and interpersonal skills
Preferred qualifications - Experience with gene editing and/or ALS therapeutic programs
- Experience with non-human primate biodistribution studies and/or IND-enabling studies
- Histology experience, including ISH and/or IHC
The anticipated salary range for candidates for this role will be $XX - $XX. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, industry knowledge, technical skills, and other factors that may prove relevant during the interview process.
