Job title: Senior Scientist, Medicinal Chemistry, Integrated Drug Discovery
About the jobAn accomplished synthetic organic and medicinal chemist, with a track record of impactful project contributions in design and synthesis.
Main Responsibilities:- Design and synthesize small molecule targets to drive programs to clinical candidate nomination.
- Use reaction and reagent databases to select effective methods/routes to maximize productivity and provide solutions to complex multi-step synthetic problems.
- Prepare and characterize high purity target compounds and intermediates to meet aggressive project timelines.
- Proficiency with the use of analytical techniques for structural characterization and ability to interpret complex NMR spectra.
- Register compounds in corporate database and maintain notebooks according to SOP.
- Champion new chemistry techniques, reagents and methodology in discovery chemistry and participate in group/lab responsibilities.
- Understand project SAR, adapt and prioritize work proactively based on emerging data.
- Interpret biological data (DMPK, pharmacology, safety) to contribute to project advancement.
- Ability to work independently, proactively and collaboratively with other team members to design compounds to address key issues.
- Dedication to lifelong learning.
- Understand and articulate the scientific rationale of the project to other scientists.
- Provide formal and informal mentoring to junior staff members.
- Determine the relevance of patent search results and assess the patentability of new targets. Assist with filing patent applications by reviewing claims and providing experimental data.
- Actively participate in medicinal chemistry discussions communicating own science in a clear and precise manner; proactively raise issues which positively influence the direction of program.
- Communicate and interact with other staff members in a professional and courteous manner.
- Operate in the lab in a safe and efficient manner according to HSE guidelines and adhere to all mandatory company compliance requirements.
- Adapt to changes and challenges in a productive and professional manner.
- Act as an ambassador for the department and attend appropriate scientific meetings to stay up to date with current literature and industry direction.
- Experience in Induced Proximity Modalities preferred
About youEducation & Experience:
- Bachelor's Degree in chemistry or related field with minimum 7 years of relevant research experience in an academic or biopharmaceutical setting OR
- Master's Degree with minimum 4 years of relevant research experience in an academic or biopharmaceutical setting OR
- PhD with minimum 2 years of relevant research experience in an academic or biopharmaceutical setting.
- Deep knowledge of organic chemistry and a growing understanding of medicinal chemistry principles.
The salary range for this position is:
$100.500,00 - $145.166,66
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.
