(Senior Manager / Associate Director) Clinical Operations

Capable Lab

$125K — $150K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • 5-7 years of experience in clinical trial management from activation to closeout.
  • Proven track record of advancing therapies toward approval or market.
  • Strong organizational skills managing multiple timelines and external partners.
  • Excellent relationship-building abilities with investigators, vendors, and stakeholders.
  • Experience in evaluating vendor performance and negotiating contracts and budgets.
  • Ability to thrive with high ownership in a fast-paced, startup environment.

Responsibilities

  • Lead clinical trials from site activation to execution, ensuring timely data delivery and study closeout.
  • Manage relationships with trial sites, laboratories, and other vendors necessary for study conduction.
  • Negotiate scopes, timelines, budgets, and deliverables with external partners to keep trials on track.
  • Develop strong collaborations with investigators and site coordinators to enhance study operations.
  • Proactively identify and address operational bottlenecks affecting recruitment, data quality, and compliance.
  • Engage with scientific partners to design studies that yield actionable human data.
  • Draft and maintain operating plans while monitoring risks, dependencies, and accountability.

Benefits

  • Generous equity options provided in addition to salary.
  • Monthly wellness budget exceeding $500 for personal development and health tools.
  • Comprehensive healthcare coverage with Capable covering 100% of the base policy.
  • Access to HSA, FSA, and 401K plans for financial well-being.
  • Daily healthy dinners provided to foster team camaraderie.
  • Support for visa sponsorships, reflecting an inclusive international team environment.
Full Job Description
About the Role

You will own the operational execution of Capable's clinical studies, turning study plans into well-run trials and decision-grade human data. Working directly with our founders, scientists, clinicians, regulatory advisors, investigators, sites, and vendors, you will anticipate bottlenecks, drive clear ownership, and keep complex external work moving on time and within scope.

Responsibilities
  • Lead clinical studies from site activation through execution, data delivery, and closeout.
  • Identify, evaluate, and manage trial sites, laboratories, manufacturers, pharmacies, IRBs, and other vendors required to run each study.
  • Negotiate scopes, budgets, timelines, deliverables, and operating expectations with external partners.
  • Build strong working relationships with investigators, site coordinators, vendors, and subject-matter experts.
  • Anticipate and resolve operational bottlenecks involving contracting, enrollment, site communication, sample handling, data lag, vendor handoffs, or protocol ambiguity.
  • Work with internal and external scientific and clinical partners to design studies that produce clear, decision-grade human data.
  • Create practical operating plans, track risks and dependencies, and ensure that decisions and next steps have clear owners.


Ideal Qualifications
  • A track record of leading multiple clinical trials from site activation through execution, data delivery, and closeout; experience helping advance a therapy toward approval or market is especially valuable.
  • Strong clinical-operations judgment and the ability to identify the few issues most likely to delay or weaken a study.
  • Excellent organization and follow-through across many external parties, timelines, and handoffs.
  • Strong relationship-building skills and a high bar for investigators, sites, and vendors.
  • Experience evaluating and negotiating vendor scopes, budgets, and timelines.
  • Comfort operating with high ownership in a fast-moving, early-stage environment.


Pay & Benefits
  • In addition to the posted salary range, we offer generous equity options.
  • Compensation will depend on the skills, experience, and scope of impact you bring. If your background, experience, or compensation needs fall outside this range, we are still open to a conversation based on the scope and impact you could bring.
  • $500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.
  • Healthcare: We offer a broad range of medical, dental, and vision coverage options, with Capable covering 100% of the base policy.
  • You will also have access to HSA, FSA, and 401K plans.
  • Healthy dinners with the team are provided daily.
  • We support visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways. Our team is already international, with members from Canada, Pakistan, Germany, Austria, Switzerland, China, India, and the United States.


Application Process

Our process is fast, transparent, and personal. We care about getting to know the person behind the application.
  • Initial application
  • First phone screen
  • Second phone screen
  • In-person work trial in San Francisco: designed to give both sides a realistic sense of working together. Get to know the founding team!


Apply Today

Curious but not sure? Apply anyway. It takes 5 minutes, and you do not need to be actively job searching to start a conversation.

Some of the best people do not map perfectly to a job description. If this sounds like a place where you could do important work, we would like to hear from you.

And if someone exceptional comes to mind, send them our way here. We read every referral carefully, and if your referral joins Capable, we'll send you a thank-you bonus.

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